Search Results - "Cheah, Shiau Chuen"

Chelerythrine Chloride Downregulates β-Catenin and Inhibits Stem Cell Properties of Non-Small Cell Lung Carcinoma by Heng, Win Sen, Cheah, Shiau-Chuen

“…Plant secondary metabolites have been seen as alternatives to seeking new medicines for treating various diseases. Phytochemical scientists remain hopeful that…”
Get full text

Development of semi‐quantitative urinary sodium test strip by Lai, Jiong Soon, Tan, Chung Keat, Yusoff, Khalid, Cheah, Shiau‐Chuen

“…Excessive salt consumption has been associated with greater risk of hypertension. Therefore, monitoring of dietary sodium consumption should be prioritized. As…”
Get full text

Identification of Phytochemical-Based β-Catenin Nuclear Localization Inhibitor in NSCLC: Differential Targeting Population from Member of Isothiocyanates by Heng, Win Sen, Cheah, Shiau-Chuen

“…Decades of research has convinced us that phytochemical compounds contained within the plant products are the real deal, and they provide benefits such as…”
Get full text

The role of Epstein-Barr virus in nasopharyngeal carcinoma by Su, Zhi Yi, Siak, Pui Yan, Leong, Chee-Onn, Cheah, Shiau-Chuen

“…Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated with the Epstein-Barr virus (EBV). Despite ubiquitous infection of EBV…”
Get full text

Antidiabetic and antioxidant properties of alkaloids from Catharanthus roseus (L.) G. Don by Tiong, Soon Huat, Looi, Chung Yeng, Hazni, Hazrina, Arya, Aditya, Paydar, Mohammadjavad, Wong, Won Fen, Cheah, Shiau-Chuen, Mustafa, Mohd Rais, Awang, Khalijah

“…Catharanthus roseus (L.) G. Don is a herbal plant traditionally used by local populations in India, South Africa, China and Malaysia to treat diabetes. The…”
Get full text

Impact of different dietary sodium reduction strategies on blood pressure: a systematic review by Lai, Jiong Soon, Aung, Yin Nwe, Khalid, Yusoff, Cheah, Shiau-Chuen

“…High sodium intake was found to be associated with increased blood pressure. Decreasing dietary sodium intake can effectively reduce blood pressure, especially…”
Get full text

Precision medicine in nasopharyngeal carcinoma: comprehensive review of past, present, and future prospect by Siak, Pui Yan, Heng, Win Sen, Teoh, Sharon Siew Hoon, Lwin, Yu Yu, Cheah, Shiau-Chuen

“…Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with high propensity for lymphatic spread and distant metastasis. It is prominent as an endemic…”
Get full text

Current Status and Future Perspectives about Molecular Biomarkers of Nasopharyngeal Carcinoma by Siak, Pui Yan, Khoo, Alan Soo-Beng, Leong, Chee Onn, Hoh, Boon-Peng, Cheah, Shiau-Chuen

“…Nasopharyngeal carcinoma (NPC) is an epithelial malignancy that shows a remarkable ethnic and geographical distribution. It is one of the major public health…”
Get full text

Nasopharyngeal Carcinoma and Its Microenvironment: Past, Current, and Future Perspectives by Su, Zhi Yi, Siak, Pui Yan, Leong, Chee-Onn, Cheah, Shiau-Chuen

“…Nasopharyngeal carcinoma (NPC) is an epithelial malignancy that raises public health concerns in endemic countries. Despite breakthroughs in therapeutic…”
Get full text

Understanding Lung Carcinogenesis from a Morphostatic Perspective: Prevention and Therapeutic Potential of Phytochemicals for Targeting Cancer Stem Cells by Heng, Win Sen, Kruyt, Frank A. E., Cheah, Shiau-Chuen

“…Lung cancer is still one of the deadliest cancers, with over two million incidences annually. Prevention is regarded as the most efficient way to reduce both…”
Get full text

Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells by Lee, Sui-Ting, Wong, Pooi-Fong, Cheah, Shiau-Chuen, Mustafa, Mohd Rais

“…Alpha-tomatine (α-tomatine) is the major saponin in tomato (Lycopersicon esculentum). This study investigates the chemopreventive potential of α-tomatine on…”
Get full text

Uridine From a Standardized Aqueous Extract of Giant Oyster Mushroom, Pleurotus giganteus Inhibits Amyloid β (Aβ)-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells by Wang, Joon Keong, Phan, Chia Wei, Cheah, Shiau-Chuen, Sabaratnam, Vikineswary

“…We examined the neuroprotective effects of a uridine (1.8%, g/100 g)-standardized Pleurotus giganteus extract on amyloid β-induced human neuroblastoma SH-SY5Y…”
Get full text

New Mn(II), Ni(II), Cd(II), Pb(II) complexes with 2-methylbenzimidazole and other ligands. Synthesis, spectroscopic characterization, crystal structure, magnetic susceptibility and biological activity studies by Shaker, Shayma A., Khaledi, Hamid, Cheah, Shiau-Chuen, Ali, Hapipah Mohd

“…Synthesis and characterization of Mn(II), Ni(II), Cd(II) and Pb(II) mixed ligand complexes of 2-methylbenzimidazole with other ligands have been reported. The…”
Get full text

C-MYC, BCL2 and BCL6 Translocation in B-cell Non-Hodgkin Lymphoma Cases by Salam, Dayang Sharyati Datu Abdul, Thit, Ei Ei, Teoh, Siew Hoon, Tan, Soo Yong, Peh, Suat Cheng, Cheah, Shiau-Chuen

“…, and genes are the most commonly oncogenes involved in B-Cell lymphomas. Translocations of these oncogenes are associated with an aggressive clinical course…”
Get full text

In vitro and in vivo anti-angiogenic activities of Panduratin A by Lai, Siew-Li, Cheah, Shiau-Chuen, Wong, Pooi-Fong, Noor, Suzita Mohd, Mustafa, Mohd Rais

“…Targeting angiogenesis has emerged as an attractive and promising strategy in anti-cancer therapeutic development. The present study investigates the…”
Get full text

Panduratin A inhibits the growth of A549 cells through induction of apoptosis and inhibition of NF-kappaB translocation by Cheah, Shiau-Chuen, Appleton, David R, Lee, Sui-Ting, Lam, May-Lynn, Hadi, A Hamid A, Mustafa, Mohd Rais

“…In the present study we investigated the effects of panduratin A, isolated from Boesenbergia rotunda, on proliferation and apoptosis in A549 human non-small…”
Get full text

Apoptosis Effect of Girinimbine Isolated from Murraya koenigii on Lung Cancer Cells In Vitro by Mohan, Syam, Abdelwahab, Siddig Ibrahim, Cheah, Shiau-Chuen, Sukari, Mohd Aspollah, Syam, Suvitha, Shamsuddin, Noorasyikin, Rais Mustafa, Mohd

“…Murraya koenigii Spreng has been traditionally claimed as a remedy for cancer. The current study investigated the anticancer effects of girinimbine, a…”
Get full text

(-)-Kunstleramide, a new antioxidant and cytotoxic dienamide from the bark of Beilschmiedia kunstleri gamble by Mollataghi, Abbas, Hadi, A Hamid A, Cheah, Shiau-Chuen

“…A new dienamide, (2E,4E)-7-(3',4'-dimethoxyphenyl)-N-ethyl-6-(R)-hydroxyhepta- 2,4-dienamide, named (-)-kunstleramide (1), were isolated from the bark of…”
Get full text

Molecular Modeling-Based Delivery System Enhances Everolimus-Induced Apoptosis in Caco‑2 Cells by Maki, Marwan Abdelmahmoud Abdelkarim, Kumar, Palanirajan Vijayaraj, Cheah, Shiau-Chuen, Siew Wei, Yeong, Al-Nema, Mayasah, Bayazeid, Omer, Majeed, Abu Bakar Bin Abdul

“…Several studies have shown that the mammalian target of rapamycin (mTOR) inhibitor; everolimus (EV) improves patient survival in several types of cancer…”
Get full text

Epidemiology of nasopharyngeal carcinoma: current insights and future outlook by Su, Zhi Yi, Siak, Pui Yan, Lwin, Yu Yu, Cheah, Shiau-Chuen

“…Nasopharyngeal carcinoma (NPC) is characterised by its remarkable geographical and ethnic distribution. The interplay between genetic susceptibility,…”
Get full text