Search Results - "Cheah, E."

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation by Yang, Liu, Tsang, Kwok Yeung, Tang, Hoi Ching, Chan, Danny, Cheah, Kathryn S. E.

“…According to current dogma, chondrocytes and osteoblasts are considered independent lineages derived from a common osteochondroprogenitor. In endochondral bone…”
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Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions by Tan, Zhijia, Niu, Ben, Tsang, Kwok Yeung, Melhado, Ian G, Ohba, Shinsuke, He, Xinjun, Huang, Yongheng, Wang, Cheng, McMahon, Andrew P, Jauch, Ralf, Chan, Danny, Zhang, Michael Q, Cheah, Kathryn S E

“…The growth plate mediates bone growth where SOX9 and GLI factors control chondrocyte proliferation, differentiation and entry into hypertrophy. FOXA factors…”
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Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner by Yang, Lu M, Cheah, Kathryn S E, Huh, Sung-Ho, Ornitz, David M

“…The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop…”
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Prevalence and Pattern of Lumbar Magnetic Resonance Imaging Changes in a Population Study of One Thousand Forty-Three Individuals by CHEUNG, Kenneth M. C, KARPPINEN, Jaro, CHAN, Danny, HO, Daniel W. H, SONG, You-Qiang, SHAM, Pak, CHEAH, Kathryn S. E, LEONG, John C. Y, LUK, Keith D. K

“…A cross-sectional population study of magnetic resonance imaging (MRI) changes. OBJECTIVE.: To examine the pattern and prevalence of lumbar spine MRI changes…”
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Measurements of Phase Dynamics in Planar Josephson Junctions and SQUIDs by Haxell, D Z, Cheah, E, Křížek, F, Schott, R, Ritter, M F, Hinderling, M, Belzig, W, Bruder, C, Wegscheider, W, Riel, H, Nichele, F

“…We experimentally investigate the stochastic phase dynamics of planar Josephson junctions (JJs) and superconducting quantum interference devices (SQUIDs)…”
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Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes by Ali, Shabana Amanda, Niu, Ben, Cheah, Kathryn S E, Alman, Benjamin

“…Excessive Hedgehog (Hh) signaling in chondrocytes is sufficient to cause formation of enchondroma-like lesions which can progress to chondrosarcoma. To…”
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Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea by Dabdoub, Alain, Puligilla, Chandrakala, Jones, Jennifer M, Fritzsch, Bernd, Cheah, Kathryn S.E, Pevny, Larysa H, Kelley, Matthew W

“…Sox2 is a high-mobility transcription factor that is one of the earliest markers of developing inner ear prosensory domains. In humans, mutations in SOX2 cause…”
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SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression by Leung, Victor Y L, Gao, Bo, Leung, Keith K H, Melhado, Ian G, Wynn, Sarah L, Au, Tiffany Y K, Dung, Nelson W F, Lau, James Y B, Mak, Angel C Y, Chan, Danny, Cheah, Kathryn S E

“…Cartilage and endochondral bone development require SOX9 activity to regulate chondrogenesis, chondrocyte proliferation, and transition to a non-mitotic…”
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SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains by Huang, Yong-Heng, Jankowski, Aleksander, Cheah, Kathryn S. E., Prabhakar, Shyam, Jauch, Ralf

“…The SOXE transcription factors SOX8, SOX9 and SOX10 are master regulators of mammalian development directing sex determination, gliogenesis, pancreas…”
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Fate of growth plate hypertrophic chondrocytes: Death or lineage extension? by Tsang, Kwok Yeung, Chan, Danny, Cheah, Kathryn S. E.

“…The vertebrate growth plate is an essential tissue that mediates and controls bone growth. It forms through a multistep differentiation process in which…”
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Sox2 is required for sensory organ development in the mammalian inner ear by Cheah, Kathryn S. E, Kiernan, Amy E, Pelling, Anna L, Leung, Keith K. H, Tang, Anna S. P, Bell, Donald M, Tease, Charles, Lovell-Badge, Robin, Steel, Karen P

“…Sensory hair cells and their associated non-sensory supporting cells in the inner ear are fundamental for hearing and balance. They arise from a common…”
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Fbxo9 functions downstream of Sox10 to determine neuron-glial fate choice in the dorsal root ganglia through Neurog2 destabilization by Liu, Jessica Aijia, Tai, Andrew, Hong, Jialin, Cheung, May Pui Lai, Sham, Mai Har, Cheah, Kathryn S. E., Cheung, Chi Wai, Cheung, Martin

“…The transcription factor Sox10 is a key regulator in the fate determination of a subpopulation of multipotent trunk neural crest (NC) progenitors toward glial…”
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Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function by Tsang, Kwok Yeung, Chan, Danny, Cheslett, Deborah, Chan, Wilson C W, So, Chi Leong, Melhado, Ian G, Chan, Tori W Y, Kwan, Kin Ming, Hunziker, Ernst B, Yamada, Yoshihiko, Bateman, John F, Cheung, Kenneth M C, Cheah, Kathryn S E

“…In protein folding and secretion disorders, activation of endoplasmic reticulum (ER) stress signaling (ERSS) protects cells, alleviating stress that would…”
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Spin-Degeneracy Breaking and Parity Transitions in Three-Terminal Josephson Junctions by Coraiola, M., Haxell, D. Z., Sabonis, D., Hinderling, M., Kate, S. C. ten, Cheah, E., Krizek, F., Schott, R., Wegscheider, W., Nichele, F.

“…Hybrid Josephson junctions (JJs) realized in superconductor-semiconductor heterostructures host fermionic modes known as Andreev bound states (ABSs). In these…”
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New perspective on the performance stability of CdTe solar cells by Gretener, C., Perrenoud, J., Kranz, L., Cheah, E., Dietrich, M., Buecheler, S., Tiwari, A.N.

“…Cu is a well-known cause for degradation of CdTe solar cells, yet, the exact mechanisms remain subject of discussion. We have chosen a novel approach to study…”
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Acquisition of multipotent and migratory neural crest cells in vertebrate evolution by Cheung, Martin, Tai, Andrew, Lu, Peter Jianning, Cheah, Kathryn SE

“…The emergence of multipotent and migratory neural crest (NC) cells defines a key evolutionary transition from invertebrates to vertebrates. Studies in…”
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Sox18 induces development of the lymphatic vasculature in mice by Karnezis, Tara, Achen, Marc G, Shayan, Ramin, Muscat, George E. O, Downes, Meredith, Orsenigo, Fabrizio, Tutt, Desmond, Wilhelm, Dagmar, Browne, Catherine, Stacker, Steven A, Dejana, Elisabetta, Davidson, Tara, Koopman, Peter, Caprini, Andrea, Paavonen, Karri, Cheah, Kathryn S. E, François, Mathias, Hosking, Brett

“…The lymphatic system plays a key role in tissue fluid regulation and tumour metastasis, and lymphatic defects underlie many pathological states including…”
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Oncogenicity of the Developmental Transcription Factor Sox9 by MATHEU, Ander, COLLADO, Manuel, SKOTHEIM, Rolf I, LOTHE, Ragnhild A, DE MUNAIN, Adolfo López, BRISCOE, James, SERRANO, Manuel, LOVELL-BADGE, Robin, WISE, Clare, MANTEROLA, Lorea, CEKAITE, Lina, TYE, Angela J, CANAMERO, Marta, BUJANDA, Luis, SCHEDL, Andreas, CHEAH, Kathryn S. E

“…SOX9 [sex-determining region Y (SRY)-box 9 protein], a high mobility group box transcription factor, plays critical roles during embryogenesis and its activity…”
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developmental roles of the extracellular matrix: beyond structure to regulation by Tsang, Kwok Yeung, Cheung, Martin C. H, Chan, Danny, Cheah, Kathryn S. E

“…Cells in multicellular organisms are surrounded by a complex three-dimensional macromolecular extracellular matrix (ECM). This matrix, traditionally thought to…”
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Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling by Liu, Jessica A. J., Wu, Ming-Hoi, Yan, Carol H., Chau, Bolton K. H., So, Henry, Ng, Alvis, Chan, Alan, Cheah, Kathryn S. E., Briscoe, James, Cheung, Martin

“…Coordination of neural crest cell (NCC) induction and delamination is orchestrated by several transcription factors. Among these, Sry-related HMG box-9 (Sox9)…”
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