Search Results - "Chazenbalk, G.D."
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Evidence for a simplified view of autoantibody interactions with the thyrotropin receptor
Published in Thyroid (New York, N.Y.) (01-02-2002)“…Recently, many exceptions have been reported that undermine the concept that the epitopes for thyroid-stimulating autoantibodies (TSAb) and…”
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Thyrotropin-Luteinizing Hormone/Chorionic Gonadotropin Receptor Extracellular Domain Chimeras as Probes for Thyrotropin Receptor Function
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1991)“…To define the sites in the extracellular domain of the human thyrotropin (TSH) receptor that are involved in TSH binding and signal transduction we constructed…”
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Cleavage of the thyrotropin receptor does not occur at a classical subtilisin-related proprotein convertase endoproteolytic site
Published in The Journal of biological chemistry (23-12-1994)“…The human thyrotropin receptor (TSHR) undergoes proteolytic cleavage closely upstream to amino acid 317. Between residues 261 and 313 are three clusters of…”
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Eleven amino acids (Lys-201 to Lys-211) and 9 amino acids (Gly-222 to Leu-230) in the human thyrotropin receptor are involved in ligand binding
Published in The Journal of biological chemistry (15-08-1991)“…Our previous studies involving chimeric thyrotropin-lutropin/choriogonadotropin (TSH-LH/CG) receptors suggest that multiple segments spanning the entire…”
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Cloning of a member of the arrestin family from a human thyroid cDNA library
Published in Molecular and cellular endocrinology (01-04-1992)“…We used the cDNA of human retinal arrestin as a probe to screen a human thyroid cDNA library. We isolated and plaque-purified one clone (hTHY-ARRX). The…”
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Thyroid autoregulation. Inhibitory effects of iodinated derivatives of arachidonic acid on iodine metabolism
Published in Prostaglandins (01-08-1988)“…Thyroid autoregulation has been linked to an organified iodocompound. Since several iodolipids are produced by the gland their possible role in thyroid…”
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