Search Results - "Chazalviel, L"
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An updated model of hydrocephalus in sheep to evaluate the performance of a device for ambulatory wireless monitoring of cerebral pressure through shunts
Published in Neuro-chirurgie (01-04-2022)“…Cerebrospinal fluid (CSF) diversion by shunts is the most common surgical treatment for hydrocephalus. Though effective, shunts are associated with risk of…”
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P.1.g.073 Pharmacological MRI: a tool to understand the paradoxical effects of serotonergic type 6 receptors modulation?
Published in European neuropsychopharmacology (01-09-2015)Get full text
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Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat
Published in The European journal of neuroscience (01-04-2006)“…The mechanisms underlying functional recovery after stroke are poorly understood. Brain‐adaptive responses to the hypoxic stress elicited by ischemia could…”
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Physical Activity Attenuates Brain Irradiation-Associated Skeletal Muscle Damage in the Rat
Published in International journal of radiation oncology, biology, physics (15-03-2024)“…Radiation therapy for brain tumors increases patient survival. Nonetheless, side effects are increasingly reported such as cognitive deficits and fatigue. The…”
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Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [64Cu][Cu(ATSM)] PET and proteomic studies
Published in EJNMMI research (25-11-2023)“…Background Brain metastases (BM) are the most frequent malignant brain tumors. The aim of this study was to characterize the tumor microenvironment (TME) of BM…”
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The underestimated effect of normobaric hyperoxia on cerebral blood flow and its relationship to neuroprotection
Published in Brain (London, England : 1878) (01-11-2016)Get full text
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Carbogen-induced increases in tumor oxygenation depend on the vascular status of the tumor: A multiparametric MRI study in two rat glioblastoma models
Published in Journal of cerebral blood flow and metabolism (01-06-2017)“…The alleviation of hypoxia in glioblastoma with carbogen to improve treatment has met with limited success. Our hypothesis is that the eventual benefits of…”
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Neuroprotective effects of xenon: a therapeutic window of opportunity in rats subjected to transient cerebral ischemia
Published in The FASEB journal (01-04-2008)“…Brain insults are a major cause of acute mortality and chronic morbidity. Given the largely ineffective current therapeutic strategies, the development of new…”
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Long-Term Functional Outcome Following Transient Middle Cerebral Artery Occlusion in the Rat: Correlation Between Brain Damage and Behavioral Impairment
Published in Behavioral neuroscience (01-12-2006)“…The assessment of both histological and functional long-term outcomes after cerebral ischemia is increasingly recommended for preclinical studies. Whereas…”
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Hyperbaric oxygen increases tissue-plasminogen activator-induced thrombolysis in vitro, and reduces ischemic brain damage and edema in rats subjected to thromboembolic brain ischemia
Published in Medical gas research (01-04-2016)“…Recent data have shown that normobaric oxygen (NBO) increases the catalytic and thrombolytic efficiency of recombinant tissue plasminogen activator (rtPA) in…”
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Reduction of Ischemic Brain Damage by Nitrous Oxide and Xenon
Published in Journal of cerebral blood flow and metabolism (01-10-2003)“…Neuronal death after ischemia-induced brain damage depends largely upon the activation of the N-methyl-D-aspartate (NMDA) excitatory glutamate receptor that is…”
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Effects of normobaric versus hyperbaric oxygen on cell injury induced by oxygen and glucose deprivation in acute brain slices
Published in Medical gas research (01-07-2016)“…Normobaric oxygen (NBO) and hyperbaric oxygen (HBO) are emerging as a possible co-treatment of acute ischemic stroke. Both have been shown to reduce infarct…”
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A Transforming Growth Factor-β Antagonist Unmasks the Neuroprotective Role of This Endogenous Cytokine in Excitotoxic and Ischemic Brain Injury
Published in Journal of cerebral blood flow and metabolism (01-12-1999)“…Various studies describe increased concentrations of transforming growth factor-β (TGF-β) in brain tissue after acute brain injury. However, the role of…”
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P22 REDUCTION OF ISCHEMIC BRAIN DAMAGE BY NITROUS OXIDE AND XENON
Published in Behavioural pharmacology (01-09-2006)Get full text
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Increased Expression of Transforming Growth Factor-β after Cerebral Ischemia in the Baboon: An Endogenous Marker of Neuronal Stress?
Published in Journal of cerebral blood flow and metabolism (01-07-2001)“…There has been an increasing interest in recent years in the evaluation of the neuronal and glial responses to ischemic insult. Some cytokines, including…”
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Evaluation in rats and primates of [ 11C]-mecamylamine, a potential nicotinic acetylcholine receptor radioligand for positron emission tomography
Published in Neurochemistry international (01-05-2005)“…Mecamylamine is a well-described non specific antagonist of nicotinic acetylcholine receptors (nAChRs), used in therapy and in psychopharmacological studies. […”
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Synthesis and radiosynthesis with a positron emitter of EP 00652218, a potent antagonist of NK1 receptor, and of a fluoro analog for in vivo evaluation of the substance P receptor by pet
Published in Journal of labelled compounds & radiopharmaceuticals (01-05-2001)“…Neurokinins (NKs) are the most important of the peptides released from neuronal sensory afferents. In mammals different NKs [substance P (SP), neurokinin A…”
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