Search Results - "Chawla, Yadya M."
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Regional Variation of the CD4 and CD8 T Cell Epitopes Conserved in Circulating Dengue Viruses and Shared with Potential Vaccine Candidates
Published in Viruses (05-05-2024)“…As dengue expands globally and many vaccines are under trials, there is a growing recognition of the need for assessing T cell immunity in addition to…”
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mltG gene deletion mitigated virulence potential of Streptococcus mutans: An in-vitro, ex-situ and in-vivo study
Published in AMB Express (20-02-2023)“…Bacterial cells are surrounded by a peptidoglycan (PG) cell wall, which is essential for cell integrity and intrinsic biogenesis pathways; hence, the cell wall…”
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Contrasting behavior between the three human monocyte subsets in dengue pathophysiology
Published in iScience (17-06-2022)“…Monocytes are known to play a critical role in dengue pathophysiology. However, which monocyte subset expresses what inflammatory mediator(s) and what…”
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Functional and transcriptional heterogeneity within the massively expanding HLADR + CD38 + CD8 T cell population in acute febrile dengue patients
Published in Journal of virology (30-11-2023)“…CD8 T cells play a crucial role in protecting against intracellular pathogens such as viruses by eliminating infected cells and releasing anti-viral cytokines…”
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Severe disease during both primary and secondary dengue virus infections in pediatric populations
Published in Nature medicine (01-03-2024)“…Dengue is a global epidemic causing over 100 million cases annually. The clinical symptoms range from mild fever to severe hemorrhage and shock, including some…”
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Immunophenotyping and Transcriptional Profiling of Human Plasmablasts in Dengue
Published in Journal of virology (09-11-2021)“…Plasmablasts represent a specialized class of antibody-secreting effector B cells that transiently appear in blood circulation following infection or…”
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Antibody response patterns in chikungunya febrile phase predict protection versus progression to chronic arthritis
Published in JCI insight (09-04-2020)“…Chikungunya virus (CHIKV) infection causes acute febrile illness in humans, and some of these individuals develop a debilitating chronic arthritis that can…”
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