Search Results - "Chaves Valadão, Ana Luiza"

SARS-CoV-2 triggers an MDA-5-dependent interferon response which is unable to control replication in lung epithelial cells by Rebendenne, Antoine, Valadão, Ana Luiza Chaves, Tauziet, Marine, Maarifi, Ghizlane, Bonaventure, Boris, McKellar, Joe, Planès, Rémi, Nisole, Sébastien, Arnaud-Arnould, Mary, Moncorgé, Olivier, Goujon, Caroline

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of coronavirus disease 19 (COVID-19), which ranges from mild respiratory…”
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Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1 by Cribier, Alexandra, Descours, Benjamin, Valadão, Ana Luiza Chaves, Laguette, Nadine, Benkirane, Monsef

“…SAMHD1 restricts HIV-1 replication in myeloid and quiescent CD4+ T cells. Here, we show that SAMHD1 restriction activity is regulated by phosphorylation…”
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Natural Plant Alkaloid (Emetine) Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity by Chaves Valadão, Ana Luiza, Abreu, Celina Monteiro, Dias, Juliana Zanatta, Arantes, Pablo, Verli, Hugo, Tanuri, Amilcar, de Aguiar, Renato Santana

“…Ipecac alkaloids are secondary metabolites produced in the medicinal plant Psychotria ipecacuanha. Emetine is the main alkaloid of ipecac and one of the active…”
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Reactivation of latent HIV-1 in vitro using an ethanolic extract from Euphorbia umbellata (Euphorbiaceae) latex by Valadão, Ana Luiza Chaves, Pezzuto, Paula, Silva, Viviane A Oliveira, Gonçalves, Barbara Simonson, Rossi, Átila Duque, da Cunha, Rodrigo Delvecchio, Siani, Antonio Carlos, Tostes, João Batista de Freitas, Trovó, Marcelo, Damasco, Paulo, Gonçalves, Gabriel, Reis, Rui Manuel, Aguiar, Renato Santana, Bento, Cleonice Alves de Melo, Tanuri, Amilcar

“…Euphorbia umbellata (E. umbellata) belongs to Euphorbiaceae family, popularly known as Janauba, and its latex contains a combination of phorbol esters with…”
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Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs by Rebendenne, Antoine, Roy, Priyanka, Bonaventure, Boris, Chaves Valadão, Ana Luiza, Desmarets, Lowiese, Arnaud-Arnould, Mary, Rouillé, Yves, Tauziet, Marine, Giovannini, Donatella, Touhami, Jawida, Lee, Yenarae, DeWeirdt, Peter, Hegde, Mudra, Urbach, Serge, Koulali, Khadija El, de Gracia, Francisco Garcia, McKellar, Joe, Dubuisson, Jean, Wencker, Mélanie, Belouzard, Sandrine, Moncorgé, Olivier, Doench, John G., Goujon, Caroline

“…CRISPR knockout (KO) screens have identified host factors regulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication. Here, we…”
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The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand RNA viruses by Bonaventure, Boris, Rebendenne, Antoine, Chaves Valadão, Ana Luiza, Arnaud‐Arnould, Mary, Gracias, Ségolène, Garcia de Gracia, Francisco, McKellar, Joe, Labaronne, Emmanuel, Tauziet, Marine, Vivet‐Boudou, Valérie, Bernard, Eric, Briant, Laurence, Gros, Nathalie, Djilli, Wassila, Courgnaud, Valérie, Parrinello, Hugues, Rialle, Stéphanie, Blaise, Mickaël, Lacroix, Laurent, Lavigne, Marc, Paillart, Jean‐Christophe, Ricci, Emiliano P, Schulz, Reiner, Jouvenet, Nolwenn, Moncorgé, Olivier, Goujon, Caroline

“…Genome‐wide screens are powerful approaches to unravel regulators of viral infections. Here, a CRISPR screen identifies the RNA helicase DDX42 as an intrinsic…”
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Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells by Planès, Rémi, Pinilla, Miriam, Santoni, Karin, Hessel, Audrey, Passemar, Charlotte, Lay, Kenneth, Paillette, Perrine, Valadão, Ana-Luiza Chaves, Robinson, Kim Samirah, Bastard, Paul, Lam, Nathaniel, Fadrique, Ricardo, Rossi, Ida, Pericat, David, Bagayoko, Salimata, Leon-Icaza, Stephen Adonai, Rombouts, Yoann, Perouzel, Eric, Tiraby, Michèle, Zhang, Qian, Cicuta, Pietro, Jouanguy, Emmanuelle, Neyrolles, Olivier, Bryant, Clare E., Floto, Andres R., Goujon, Caroline, Lei, Franklin Zhong, Martin-Blondel, Guillaume, Silva, Stein, Casanova, Jean-Laurent, Cougoule, Céline, Reversade, Bruno, Marcoux, Julien, Ravet, Emmanuel, Meunier, Etienne

“…Inflammation observed in SARS-CoV-2-infected patients suggests that inflammasomes, proinflammatory intracellular complexes, regulate various steps of…”
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DNA damage repair kinase DNA‐PK and cGAS synergize to induce cancer‐related inflammation in glioblastoma by Taffoni, Clara, Marines, Johanna, Chamma, Hanane, Guha, Soumyabrata, Saccas, Mathilde, Bouzid, Amel, Valadao, Ana‐Luiza Chaves, Maghe, Clément, Jardine, Jane, Park, Mi Kyung, Polak, Katarzyna, De Martino, Mara, Vanpouille‐Box, Claire, Del Rio, Maguy, Gongora, Celine, Gavard, Julie, Bidère, Nicolas, Song, Min Sup, Pineau, Donovan, Hugnot, Jean‐Philippe, Kissa, Karima, Fontenille, Laura, Blanchet, Fabien P, Vila, Isabelle K, Laguette, Nadine

“…Cytosolic DNA promotes inflammatory responses upon detection by the cyclic GMP‐AMP (cGAMP) synthase (cGAS). It has been suggested that cGAS downregulation is…”
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Development of a rapid phenotypic test for HCV protease inhibitors with potential use in clinical decisions by Pessoa, Luciana Santos, Vidal, Luãnna Liebscher, Costa, Emmerson C B da, Abreu, Celina Monteiro, Cunha, Rodrigo Delvecchio da, Valadão, Ana Luiza Chaves, Santos, André Felipe Dos, Tanuri, Amilcar

“…Approximately 185 million people worldwide are chronically infected with hepatitis C virus (HCV). The first-wave of approved NS3 protease inhibitors (PIs) were…”
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2´,3´-Dialdehyde of ATP, ADP, and adenosine inhibit HIV-1 reverse transcriptase and HIV-1 replication by Schachter, Julieta, Valadao, Ana Luiza Chaves, Aguiar, Renato Santana, Barreto-de-Souza, Victor, Rossi, Atila Duque, Arantes, Pablo Ricardo, Verli, Hugo, Quintana, Paula Gabriela, Heise, Norton, Tanuri, Amilcar, Bou-Habib, Dumith Chequer, Persechini, Pedro Muanis

“…The 2´3´-dialdehyde of ATP or oxidized ATP (oATP) is a compound known for specifically making covalent bonds with the nucleotide-binding site of several…”
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Interplay between Inflammation and Cellular Stress Triggered by Flaviviridae Viruses by Valadão, Ana L C, Aguiar, Renato S, de Arruda, Luciana B

“…The Flaviviridae family comprises several human pathogens, including Dengue, Zika, Yellow Fever, West Nile, Japanese Encephalitis viruses, and Hepatitis C…”
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Genotypic Analysis of the gp41 HR1 Region From HIV-1 isolates From Enfuvirtide-Treated and Untreated Patients by Pessoa, Luciana Santos, Valadão, Ana Luiza Chaves, Abreu, Celina Monteiro, Calazans, Alexandre Rodrigues, Martins, Angélica Nascimento, Azevedo, Suwellen S S D, Couto-Fernandez, José Carlos, Azevedo, Marcelo C M V, Tanuri, Amilcar

“…OBJECTIVE:To evaluate the polymorphisms and resistance mutations in gp41 HR1 region of HIV-1. METHODS:The study included 28 HIV-positive patients undergoing…”
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Reactivation of latent HIV-1 in vitro using an ethanolic extract from Euphorbia umbellata by Valadão, Ana Luiza Chaves, Pezzuto, Paula, Silva, Viviane A. Oliveira, Gonçalves, Barbara Simonson, Rossi, Átila Duque, da Cunha, Rodrigo Delvecchio, Siani, Antonio Carlos, Tostes, João Batista de Freitas, Trovó, Marcelo, Damasco, Paulo, Gonçalves, Gabriel, Reis, Rui Manuel, Aguiar, Renato Santana, Bento, Cleonice Alves de Melo, Tanuri, Amilcar

“…Euphorbia umbellata (E. umbellata) belongs to Euphorbiaceae family, popularly known as Janauba, and its latex contains a combination of phorbol esters with…”
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Genotypic Analysis of the gp41 HR1 Region From HIV-1 isolates From Enfuvirtide-Treated and Untreated Patients: AIDS Research in Brazil by SANTOS PESSOA, Luciana, CHAVES VALADAO, Ana Luiza, MONTEIRO ABREU, Celina, RODRIGUES CALAZANS, Alexandre, NASCIMENTO MARTINS, Angélica, AZEVEDO, Suwellen S. S. D, COUTO-FERNANDEZ, José Carlos, AZEVEDO, Marcelo C. M. V, TANURI, Amilcar

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