Search Results - "Chaves, Rodrigo Dos Santos"

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  1. 1

    Heads Up! Interlinked Amyloidogenic and Axonal Transport Pathways in Concussion-Induced Neurodegeneration by Almenar-Queralt, Angels, dos Santos Chaves, Rodrigo, Kwon, Ester J., Shah, Sameer B

    “…Mild traumatic brain injury (mTBI), a condition in which brain function is transiently disrupted by a mechanical force, is a major risk factor for developing…”
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    Journal Article
  2. 2

    Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization by Langness, Vanessa F, van der Kant, Rik, Das, Utpal, Wang, Louie, Chaves, Rodrigo Dos Santos, Goldstein, Lawrence S B

    Published in Molecular biology of the cell (01-02-2021)
    “…Amyloid beta (Aβ) is a major component of amyloid plaques, which are a key pathological hallmark found in the brains of Alzheimer's disease (AD) patients. We…”
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    Journal Article
  3. 3

    Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes by Fong, Lauren K., Yang, Max M., dos Santos Chaves, Rodrigo, Reyna, Sol M., Langness, Vanessa F., Woodruff, Grace, Roberts, Elizabeth A., Young, Jessica E., Goldstein, Lawrence S.B.

    Published in The Journal of biological chemistry (20-07-2018)
    “…Mounting evidence suggests that alterations in cholesterol homeostasis are involved in Alzheimer's disease (AD) pathogenesis. Amyloid precursor protein (APP)…”
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    Journal Article