Search Results - "Chaves, H"

Vitamin D and the risk of dementia and Alzheimer disease by Littlejohns, Thomas J, Henley, William E, Lang, Iain A, Annweiler, Cedric, Beauchet, Olivier, Chaves, Paulo H.M, Fried, Linda, Kestenbaum, Bryan R, Kuller, Lewis H, Langa, Kenneth M, Lopez, Oscar L, Kos, Katarina, Soni, Maya, Llewellyn, David J

“…OBJECTIVE:To determine whether low vitamin D concentrations are associated with an increased risk of incident all-cause dementia and Alzheimer disease…”
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Prevention of falls in older people living in the community by Vieira, Edgar R, Palmer, Richard C, Chaves, Paulo H M

“…The number of people living into older age (=65 years) is rising rapidly. Older people are more likely to fall and this has adverse consequences for their…”
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Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality by Bhatt, Surya P, Balte, Pallavi P, Schwartz, Joseph E, Cassano, Patricia A, Couper, David, Jacobs, David R, Kalhan, Ravi, O’Connor, George T, Yende, Sachin, Sanders, Jason L, Umans, Jason G, Dransfield, Mark T, Chaves, Paulo H, White, Wendy B, Oelsner, Elizabeth C

“…IMPORTANCE: According to numerous current guidelines, the diagnosis of chronic obstructive pulmonary disease (COPD) requires a ratio of the forced expiratory…”
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Leptomeningeal Interfoliar Enhancement on Vessel Wall MR Imaging as a Unique Radiologic Finding of Susac Syndrome by Cardozo, P, Marrodán, M, Gilmore, A, Fiol, M P, Chaves, H

“…Susac syndrome is a rare disorder affecting the brain, retina, and inner ear, probably triggered by an immune-mediated endotheliopathy. Diagnosis is based on…”
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Association of mitochondrial DNA levels with frailty and all-cause mortality by Ashar, Foram N., Moes, Anna, Moore, Ann Z., Grove, Megan L., Chaves, Paulo H. M., Coresh, Josef, Newman, Anne B., Matteini, Amy M., Bandeen-Roche, Karen, Boerwinkle, Eric, Walston, Jeremy D., Arking, Dan E.

“…Mitochondrial function is altered with age and variants in mitochondrial DNA (mtDNA) modulate risk for several age-related disease states. However, the…”
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Red Cell Distribution Width and Mortality in Older Adults: A Meta-analysis by Patel, Kushang V., Semba, Richard D., Ferrucci, Luigi, Newman, Anne B., Fried, Linda P., Wallace, Robert B., Bandinelli, Stefania, Phillips, Caroline S., Yu, Binbing, Connelly, Stephanie, Shlipak, Michael G., Chaves, Paulo H. M., Launer, Lenore J., Ershler, William B., Harris, Tamara B., Longo, Dan L., Guralnik, Jack M.

“…Background Red cell distribution width (RDW) is a quantitative measure of variability in the size of circulating erythrocytes with higher values reflecting…”
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Life-Space Constriction, Development of Frailty, and the Competing Risk of Mortality : The Women's Health and Aging Study I by XUE, Qian-Li, FRIED, Linda P, GLASS, Thomas A, LAFFAN, Alison, CHAVES, Paulo H. M

“…Frailty is a common clinical syndrome in older adults that carries an increased risk for poor health outcomes. Little is known about the behavioral antecedents…”
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Patterns of 12-Year Change in Physical Activity Levels in Community-Dwelling Older Women: Can Modest Levels of Physical Activity Help Older Women Live Longer? by XUE, Qian-Li, BANDEEN-ROCHE, Karen, ROYCHOUDHURY, Arindam, VARADHAN, Ravi, WENLIANG YAO, FRIED, Linda P, MIELENZ, Thelma J, SEPLAKI, Christopher L, SZANTON, Sarah L, THORPE, Roland J, KALYANI, Rita R, CHAVES, Paulo H. M, DAM, Thuy-Tien L, ORNSTEIN, Katherine

“…Few studies have addressed changes in physical activity participation over time among the elderly. The authors hypothesized that there were distinct…”
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Hypertension, White Matter Hyperintensities, and Concurrent Impairments in Mobility, Cognition, and Mood: The Cardiovascular Health Study by HAJJAR, Ihab, QUACH, Lien, YANG, Frances, CHAVES, Paulo H. M, NEWMAN, Anne B, MUKAMAL, Kenneth, LONGSTRETH, Will, INZITARI, Marco, LIPSITZ, Lewis A

“…Our objective was to investigate the association between hypertension and concurrent impairments in mobility, cognition, and mood; the role of brain white…”
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Examining the Causal Mediating Role of Cardiovascular Disease on the Effect of Subclinical Cardiovascular Disease on Cognitive Impairment via Separable Effects by Andrews, Ryan M, Shpitser, Ilya, Didelez, Vanessa, Chaves, Paulo H M, Lopez, Oscar L, Carlson, Michelle C

“…Abstract Background An important epidemiological question is understanding how vascular risk factors contribute to cognitive impairment. Using data from the…”
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Identification of Potential Antiviral Inhibitors from Hydroxychloroquine and 1,2,4,5-Tetraoxanes Analogues and Investigation of the Mechanism of Action in SARS-CoV-2 by Ramos, Ryan S, Borges, Rosivaldo S, de Souza, João S N, Araujo, Inana F, Chaves, Mariana H, Santos, Cleydson B R

“…This study aimed to identify potential inhibitors and investigate the mechanism of action on SARS-CoV-2 ACE2 receptors using a molecular modeling study and…”
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Serum 25-Hydroxyvitamin D and Physical Function in Older Adults: The Cardiovascular Health Study All Stars by Houston, Denise K., Tooze, Janet A., Davis, Cralen C., Chaves, Paulo H. M., Hirsch, Calvin H., Robbins, John A., Arnold, Alice M., Newman, Anne B., Kritchevsky, Stephen B.

“…Objectives To examine the association between 25‐hydroxyvitamin D (25(OH)D) and physical function in adults of advanced age. Design Cross‐sectional and…”
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Rational Approach toward COVID-19's Main Protease Inhibitors: A Hierarchical Biochemoinformatics Analysis by Bastos, Ruan S, de Aguiar, Christiane P O, Cruz, Jorddy N, Ramos, Ryan S, Kimani, Njogu M, de Souza, João S N, Chaves, Mariana H, de Freitas, Humberto F, Pita, Samuel S R, Santos, Cleydson B R Dos

“…This study investigated the potential of selected compounds as inhibitors of SARS-CoV-2 M through pharmacokinetic and toxicological analyses, molecular…”
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The Role of Energetic Cost in the Age-Related Slowing of Gait Speed by Schrack, Jennifer A., Simonsick, Eleanor M., Chaves, Paulo H.M., Ferrucci, Luigi

“…Objectives To determine whether slow gait represents a compensatory strategy to reduce the energetic cost of walking with age. Design Cross‐sectional analysis…”
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Can a Healthy Lifestyle Compress the Disabled Period in Older Adults? by Jacob, Mini E., Yee, Laura M., Diehr, Paula H., Arnold, Alice M., Thielke, Stephen M., Chaves, Paulo H. M., Gobbo, Liana Del, Hirsch, Calvin, Siscovick, David, Newman, Anne B.

“…Objectives To determine whether lifestyle factors, measured late in life, could compress the disabled period toward the end of life. Design Community‐based…”
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Heterogeneity in Rate of Decline in Grip, Hip, and Knee Strength and the Risk of All-Cause Mortality: The Women's Health and Aging Study II by Xue, Qian-Li, Beamer, Brock A., Chaves, Paulo H.M., Guralnik, Jack M., Fried, Linda P.

“…OBJECTIVES: To assess the relationship between rate of change in muscle strength and all‐cause mortality. DESIGN: Prospective observational study of the causes…”
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Modification of the Association Between Ambient Air Pollution and Lung Function by Frailty Status Among Older Adults in the Cardiovascular Health Study by ECKEL, Sandrah P, LOUIS, Thomas A, CHAVES, Paulo H. M, FRIED, Linda P, MARGOLIS, Helene G

“…The susceptibility of older adults to the health effects of air pollution is well-recognized. Advanced age may act as a partial surrogate for conditions…”
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Long-term assessment of inflammation and healthy aging in late life: the Cardiovascular Health Study All Stars by Jenny, Nancy S, French, Benjamin, Arnold, Alice M, Strotmeyer, Elsa S, Cushman, Mary, Chaves, Paulo H M, Ding, Jingzhong, Fried, Linda P, Kritchevsky, Stephen B, Rifkin, Dena E, Sarnak, Mark J, Newman, Anne B

“…Associations of inflammation with age-related pathologies are documented; however, it is not understood how changes in inflammation over time impact healthy…”
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Organic metabolites in exhaled human breath—A multivariate approach for identification of biomarkers in lung disorders by Gaspar, Elvira M., Lucena, Ana F., Duro da Costa, J., Chaves das Neves, H.

“…The gas chromatographic profiles of exhaled air from lung cancer patients have been investigated. The breath from healthy volunteers, smokers and non-smokers,…”
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Anemia and 9-Year Domain-Specific Cognitive Decline in Community-Dwelling Older Women: The Women's Health and Aging Study II by Deal, Jennifer A., Carlson, Michelle C., Xue, Qian-Li, Fried, Linda P., Chaves, Paulo H. M.

“…OBJECTIVES: To test the hypothesis that anemia (hemoglobin <12 g/dL) is associated with a faster rate of cognitive decline over 9 years in a community‐dwelling…”
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