Search Results - "Chaves, F. Javier"

The association of urine metals and metal mixtures with cardiovascular incidence in an adult population from Spain: the Hortega Follow-Up Study by Domingo-Relloso, Arce, Grau-Perez, Maria, Briongos-Figuero, Laisa, Gomez-Ariza, Jose L, Garcia-Barrera, Tamara, Dueñas-Laita, Antonio, Bobb, Jennifer F, Chaves, F Javier, Kioumourtzoglou, Marianthi-Anna, Navas-Acien, Ana, Redon-Mas, Josep, Martin-Escudero, Juan C, Tellez-Plaza, Maria

“…Abstract Background The association of low-level exposure to metals and metal mixtures with cardiovascular incidence in the general population has rarely been…”
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Urinary metals and metal mixtures and oxidative stress biomarkers in an adult population from Spain: The Hortega Study by Domingo-Relloso, Arce, Grau-Perez, Maria, Galan-Chilet, Inmaculada, Garrido-Martinez, Maria J., Tormos, Carmen, Navas-Acien, Ana, Gomez-Ariza, Jose L., Monzo-Beltran, Lidia, Saez-Tormo, Guillermo, Garcia-Barrera, Tamara, Dueñas Laita, Antonio, Briongos Figuero, Laisa S., Martin-Escudero, Juan C., Chaves, F. Javier, Redon, Josep, Tellez-Plaza, Maria

“…Few studies have investigated the role of exposure to metals and metal mixtures on oxidative stress in the general population. We evaluated the cross-sectional…”
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Arsenic exposure, diabetes-related genes and diabetes prevalence in a general population from Spain by Grau-Perez, Maria, Navas-Acien, Ana, Galan-Chilet, Inmaculada, Briongos-Figuero, Laisa S., Morchon-Simon, David, Bermudez, Jose D., Crainiceanu, Ciprian M., de Marco, Griselda, Rentero-Garrido, Pilar, Garcia-Barrera, Tamara, Gomez-Ariza, Jose L., Casasnovas, Jose A., Martin-Escudero, Juan C., Redon, Josep, Chaves, F. Javier, Tellez-Plaza, Maria

“…Inorganic arsenic exposure may be associated with diabetes, but the evidence at low-moderate levels is not sufficient. Polymorphisms in diabetes-related genes…”
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Urine cadmium levels and albuminuria in a general population from Spain: A gene-environment interaction analysis by Grau-Perez, Maria, Pichler, Gernot, Galan-Chilet, Inma, Briongos-Figuero, Laisa S., Rentero-Garrido, Pilar, Lopez-Izquierdo, Raul, Navas-Acien, Ana, Weaver, Virginia, García-Barrera, Tamara, Gomez-Ariza, Jose L., Martín-Escudero, Juan C., Chaves, F. Javier, Redon, Josep, Tellez-Plaza, Maria

“…The interaction of cadmium with genes involved in oxidative stress, cadmium metabolism and transport pathways on albuminuria can provide biological insight on…”
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In silico epigenetics of metal exposure and subclinical atherosclerosis in middle aged men: pilot results from the Aragon Workers Health Study by Riffo-Campos, Angela L., Fuentes-Trillo, Azahara, Tang, Wan Y., Soriano, Zoraida, De Marco, Griselda, Rentero-Garrido, Pilar, Adam-Felici, Victoria, Lendinez-Tortajada, Veronica, Francesconi, Kevin, Goessler, Walter, Ladd-Acosta, Christine, Leon-Latre, Montse, Casasnovas, Jose A., Chaves, F. Javier, Navas-Acien, Ana, Guallar, Eliseo, Tellez-Plaza, Maria

“…We explored the association of metal levels with subclinical atherosclerosis and epigenetic changes in relevant biological pathways. Whole blood DNA Infinium…”
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Ambient air pollution and thyroid function in Spanish adults. A nationwide population-based study (Di@bet.es study) by Valdés, Sergio, Doulatram-Gamgaram, Viyey, Maldonado-Araque, Cristina, Lago-Sampedro, Ana, García-Escobar, Eva, García-Serrano, Sara, García-Vivanco, Marta, Garrido Juan, Luis, Theobald, Mark Richard, Gil, Victoria, Martín-Llorente, Fernando, Ocon, Pilar, Calle-Pascual, Alfonso, Castaéo, Luis, Delgado, Elías, Menendez, Edelmiro, Franch-Nadal, Josep, Gaztambide, Sonia, Girbés, Joan, Chaves, F Javier, Galán-García, José L, Aguilera-Venegas, Gabriel, Gutierrez-Repiso, Carolina, Fernández-García, José Carlos, Colomo, Natalia, Soriguer, Federico, García-Fuentes, Eduardo, Rojo-Martínez, Gemma

“…Abstract Background Recent reports have suggested that air pollution may impact thyroid function, although the evidence is still scarce and inconclusive. In…”
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Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study by Galvez-Fernandez, Marta, Sanchez-Saez, Francisco, Domingo-Relloso, Arce, Rodriguez-Hernandez, Zulema, Tarazona, Sonia, Gonzalez-Marrachelli, Vannina, Grau-Perez, Maria, Morales-Tatay, Jose M., Amigo, Nuria, Garcia-Barrera, Tamara, Gomez-Ariza, Jose L., Chaves, F. Javier, Garcia-Garcia, Ana Barbara, Melero, Rebeca, Tellez-Plaza, Maria, Martin-Escudero, Juan C., Redon, Josep, Monleon, Daniel

“…Limited studies have evaluated the joint influence of redox-related metals and genetic variation on metabolic pathways. We analyzed the association of 11…”
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Reference values for TSH may be inadequate to define hypothyroidism in persons with morbid obesity: Di@bet.es study by Valdés, Sergio, Maldonado‐Araque, Cristina, Lago‐Sampedro, Ana, Lillo‐Muñoz, Juan Antonio, Garcia‐Fuentes, Eduardo, Perez‐Valero, Vidal, Gutiérrez‐Repiso, Carolina, Garcia‐Escobar, Eva, Goday, Albert, Urrutia, Inés, Peláez, Laura, Calle‐Pascual, Alfonso, Bordiú, Elena, Castaño, Luis, Castell, Conxa, Delgado, Elias, Menéndez, Edelmiro, Franch‐Nadal, Josep, Gaztambide, Sonia, Girbés, Joan, Ortega, Emilio, Vendrell, Joan, Chacón, Matilde R., Javier Chaves, F., Soriguer, Federico, Rojo‐Martínez, Gemma

“…Objective To analyze the reference range of thyroid‐stimulating hormone (TSH) in different BMI categories and its impact on the classification of…”
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Altered glutathione system is associated with the presence of distal symmetric peripheral polyneuropathy in type 2 diabetic subjects by Mendez, Mercedes Molina, Folgado, José, Tormo, Carmen, Artero, Ana, Ascaso, Maria, Martinez-Hervás, Sergio, Chaves, F. Javier, Ascaso, Juan F, Real, Jose T

“…Abstract Distal symmetric peripheral polyneuropathy (DSPN) is a highly prevalent complication of diabetes. However, underlying pathophysiological mechanisms…”
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Do genes modify the association of selenium and lipid levels? by Galan-Chilet, Inmaculada, Guallar, Eliseo, Martin-Escudero, J Carlos, De Marco, Griselda, Dominguez-Lucas, Alejandro, Gonzalez-Manzano, Isabel, Lopez-Izquierdo, Raul, Redon, Josep, Chaves, F Javier, Tellez-Plaza, Maria

“…The interaction of selenium, a component of antioxidant selenoproteins, with genetic variation in lipid-related pathways has not been evaluated earlier as a…”
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The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control study by Mansego, Maria L, De Marco, Griselda, Ivorra, Carmen, Lopez-Izquierdo, Raúl, Morcillo, Sonsoles, Rojo-Martínez, Gemma, González-Albert, Verónica, Martinez, Fernando, Soriguer, Federico, Martín-Escudero, Juan C, Redon, Josep, Chaves, F Javier

“…Abdominal obesity (AO) is a common modifiable risk factor for certain non-communicable diseases associated with enhanced oxidative stress (OS). The objective…”
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Plasma homocysteine levels are independently associated with the severity of peripheral polyneuropathy in type 2 diabetic subjects by González, Ricardo, Pedro, Teresa, Martinez-Hervas, Sergio, Civera, Miguel, Antonia Priego, Maria, Catalá, Miguel, Javier Chaves, F., Ascaso, Juan F., Carmena, Rafael, Real, Jose T.

“…Peripheral polyneuropathy (PN) is a frequent complication of diabetes. However, mechanisms underlying the development of PN are multifactorial and not well…”
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Oxidative stress and antioxidant enzyme values in lymphomonocytes after an oral unsaturated fat load test in familial hypercholesterolemic subjects by Pedro, Teresa, Martinez-Hervas, Sergio, Tormo, Carmen, García-García, Ana Barbara, Saez-Tormo, Guillermo, Ascaso, Juan F, Chaves, F. Javier, Carmena, Rafael, Real, Jose T

“…Oxidative stress (OS) has been observed in conditions affecting the cardiovascular system. Familial hypercholesterolemia (FH) is associated with an increased…”
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Association of C677T Polymorphism in MTHFR Gene, High Homocysteine and Low HDL Cholesterol Plasma Values in Heterozygous Familial Hypercholesterolemia by Real, Jose T, Martinez-Hervas, Sergio, Garcia-Garcia, Ana Barbara, Chaves, F Javier, Civera, Miguel, Ascaso, Juan F, Carmena, Rafael

“…Aim: to investigate the association of C677T polymorphism in the methylene tetrahydrofolate reductase (MTHFR) gene, homocysteine plasma values (Hcy), and…”
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Increased oxidative stress levels and normal antioxidant enzyme activity in circulating mononuclear cells from patients of familial hypercholesterolemia by Real, Jose T, Martínez-Hervás, Sergio, Tormos, M. Carmen, Domenech, Elena, Pallardó, Federico V, Sáez-Tormo, Guillermo, Redon, Josep, Carmena, Rafael, Chaves, F. Javier, Ascaso, Juan F, García-García, Ana-Barbara

“…Abstract Familial hypercholesterolemia (FH) is a clinical condition with high risk for developing atherosclerosis. Increased oxidative stress (OS) and FH have…”
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Corrigendum to “Genetic interaction in the association between oxidative stress and diabetes in the Spanish population” [Free Radic. Biol. Med. 205 (2023) 62–68] by Melero, Rebeca, Quiroz-Rodríguez, Maria Elena, Lara-Hernández, Francisco, Redón, Josep, Sáez, Guillermo, Briongos-Figuero, Laisa S., Abadía-Otero, Jessica, Martín-Escudero, Juan Carlos, Chaves, F. Javier, Ayala, Guillermo, García-García, Ana-Bárbara

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Genetic interaction in the association between oxidative stress and diabetes in the Spanish population by Melero, Rebeca, Quiroz-Rodríguez, Maria Elena, Lara-Hernández, Francisco, Redón, Josep, Sáez, Guillermo, Briongos-Figuero, Laisa S., Abadía-Otero, Jessica, Martín-Escudero, Juan Carlos, Chaves, F. Javier, Ayala, Guillermo, García-García, Ana-Bárbara

“…Oxidative stress (OS) is a relevant intermediate mechanism involved in Type 2 Diabetes Mellitus (T2D) development. To date, the interaction between OS…”
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Metabolomic patterns, redox-related genes and metals, and bone fragility endpoints in the Hortega Study by Galvez-Fernandez, Marta, Rodriguez-Hernandez, Zulema, Grau-Perez, Maria, Chaves, F. Javier, Garcia-Garcia, Ana Barbara, Amigo, Nuria, Monleon, Daniel, Garcia-Barrera, Tamara, Gomez-Ariza, Jose L., Briongos-Figuero, Laisa S., Perez-Castrillon, Jose L., Redon, Josep, Tellez-Plaza, Maria, Martin-Escudero, Juan C.

“…The potential joint influence of metabolites on bone fragility has been rarely evaluated. We assessed the association of plasma metabolic patterns with bone…”
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EOSAL-CNV for Easy and Rapid Detection of CNVs by Fragment Analysis : EOSAL: A Fast and Reliable New Method for CNV Detection by Lara-Hernandez, Francisco, Cortez, Jessica, Garcia-Sorribes, Soraya, Blesa, Sebastian, Olivares, M Dolores, Alic, Andy S, Garcia-Garcia, Ana-Barbara, Chaves, F Javier, Ivorra, Carmen

“…Copy number variations (CNVs) are a type of genetic variation involving from 50 base pairs (bps) to millions of bps and, in a general point of view, can…”
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Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis by Morales‐Ibanez, Oriol, Domínguez, Marlene, Ki, Sung H., Marcos, Miguel, Chaves, Javier F., Nguyen‐Khac, Eric, Houchi, Hakim, Affò, Silvia, Sancho‐Bru, Pau, Altamirano, José, Michelena, Javier, García‐Pagán, Juan Carlos, Abraldes, Juan G., Arroyo, Vicente, Caballería, Juan, Laso, Francisco‐Javier, Gao, Bin, Bataller, Ramón

“…We identified, in the transcriptome analysis of patients with alcoholic hepatitis (AH), osteopontin (OPN) as one of the most up‐regulated genes. Here, we used…”
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