Effect of treatment time on performance of nano-encapsulated fluoride dentifrices for remineralization of initial carious lesions: an in vitro study

Effect of treatment time on performance of nano-encapsulated fluoride dentifrices for remineralization of initial carious lesions: an in vitro study

ABSTRACT The aim of this in vitro study was to evaluate the influence of treatment time on the remineralization performance of nanoencapsulated fluoride dentifrices on initial carious lesions. Ninety-six human enamel samples were allocated to eight groups (n = 12): 50% NanoF + 50% free NaF, 100% Nan...

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Bibliographic Details
Published in:Acta odontológica latinoamericana Vol. 34; no. 1; pp. 56 - 62
Main Authors: Oliveira, Andressa Fb, Sousa, Elizabeth Bg, Fernandes, Nayanna Ls, Meira, Ingrid A, Lavôr, Juliane R, Chaves, Ana Mbp, Sampaio, Fábio C
Format: Journal Article
Language:English
Portuguese
Published: Sociedad Argentina de Investigación Odontológica 01-04-2021
Subjects:
Dentistry
DENTISTRY, ORAL SURGERY & MEDICINE
dentifrícios
dental caries
nanotecnologia
fluorides
nanotechnology
cárie dentària
fluoretos
dentifrice
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Summary:ABSTRACT The aim of this in vitro study was to evaluate the influence of treatment time on the remineralization performance of nanoencapsulated fluoride dentifrices on initial carious lesions. Ninety-six human enamel samples were allocated to eight groups (n = 12): 50% NanoF + 50% free NaF, 100% NanoF, 100% NaF (positive control), and placebo (negative control), using two different treatment times (one and five minutes) for each dentifrice tested. After the carious lesion induction, the specimens were submitted to a pH remineralizing cycling model for seven days. Surface microhardness was measured before and after carious lesion induction and after treatment. The percentage of surface remineralization was calculated for each study time. Data were analyzed using two-way ANOVA and ANOVA repeated-measures tests followed by the Bonferroni correction (p < 0.05). Remineralization differences were observed in the dentifrices analyzed according to the treatment time used. NanoF formulations with 50% (one-min treatment) and 100% (five-min treatment) promoted significant remineralization of enamel after the caries challenge when compared to the placebo dentifrice (p < 0.05). Thus, time was considered an important factor for the fluoride release system. Nanotechnology can be a promising system for caries remineralization as it makes fluoride available on the dental surface for a longer time.
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ISSN:1852-4834
1852-4834
DOI:10.54589/aol.34/1/056