Search Results - "Chavda, Kalyan"
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Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding
Published in Trends in microbiology (Regular ed.) (01-12-2014)“…Highlights • Active spread of Klebsiella pneumoniae carbapenemases (KPCs) occurs through transposons, plasmids, and epidemic clones. • Certain KPC-producing…”
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Emergence of Ceftazidime-Avibactam Resistance Due to Plasmid-Borne blaKPC-3 Mutations during Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections
Published in Antimicrobial agents and chemotherapy (01-03-2017)“…Ceftazidime-avibactam is a novel β-lactam/β-lactamase inhibitor with activity against carbapenem-resistant Enterobacteriaceae (CRE) that produce Klebsiella…”
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Molecular dissection of the evolution of carbapenem-resistant multilocus sequence type 258 Klebsiella pneumoniae
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-2014)“…Infections caused by drug-resistant bacteria are a major problem worldwide. Carbapenem-resistant Klebsiella pneumoniae , most notably isolates classified as…”
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Colistin- and Carbapenem-Resistant Escherichia coli Harboring mcr-1 and blaNDM-5, Causing a Complicated Urinary Tract Infection in a Patient from the United States
Published in mBio (30-08-2016)“…Colistin is increasingly used as an antibiotic of last resort for the treatment of carbapenem-resistant Gram-negative infections. The plasmid-borne colistin…”
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Coidentification of mcr-4.3 and blaNDM-1 in a Clinical Enterobacter cloacae Isolate from China
Published in Antimicrobial agents and chemotherapy (01-10-2018)“…We describe the first report of a clinical colistin-resistant ST84 Enterobacter cloacae isolate coharboring mcr-4.3 (previously named mcr-4.2) and blaNDM-1…”
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Complete Sequences of mcr-1-Harboring Plasmids from Extended-Spectrum-β-Lactamase- and Carbapenemase-Producing Enterobacteriaceae
Published in Antimicrobial agents and chemotherapy (01-07-2016)“…Here we completely sequenced four mcr-1-haboring plasmids, isolated from two extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli and two…”
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Comprehensive Genome Analysis of Carbapenemase-Producing Enterobacter spp.: New Insights into Phylogeny, Population Structure, and Resistance Mechanisms
Published in mBio (13-12-2016)“…Knowledge regarding the genomic structure of Enterobacter spp., the second most prevalent carbapenemase-producing Enterobacteriaceae, remains limited. Here we…”
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Genomic Characterization of Two KPC-Producing Klebsiella Isolates Collected in 1997 in New York City
Published in Antimicrobial agents and chemotherapy (01-04-2017)“…carbapenemase (KPC)-producing have now become a global public health threat. However, the origin of this pandemic and the characterization of pre-2003…”
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Genomic Characterization of Enterobacter cloacae Isolates from China That Coproduce KPC-3 and NDM-1 Carbapenemases
Published in Antimicrobial agents and chemotherapy (01-04-2016)“…Here, we report twoEnterobacter cloacaesequence type 231 isolates coproducing KPC-3 and NDM-1 that have caused lethal infections in a tertiary hospital in…”
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Detection of the mcr-1 Colistin Resistance Gene in Carbapenem-Resistant Enterobacteriaceae from Different Hospitals in China
Published in Antimicrobial agents and chemotherapy (01-08-2016)“…The spread of the plasmid-mediated colistin resistance gene, mcr-1, into carbapenem-resistant Enterobacteriaceae (CRE) clinical isolates poses a significant…”
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Molecular Diversity and Plasmid Analysis of KPC-Producing Escherichia coli
Published in Antimicrobial agents and chemotherapy (01-07-2016)“…The emergence and spread of Klebsiella pneumoniae carbapenemase (KPC) among Enterobacteriaceae presents a major public health threat to the world. Although not…”
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A Two-Year Surveillance in Five Colombian Tertiary Care Hospitals Reveals High Frequency of Non-CG258 Clones of Carbapenem-Resistant Klebsiella pneumoniae with Distinct Clinical Characteristics
Published in Antimicrobial agents and chemotherapy (01-01-2016)“…The global spread of carbapenem-resistant Klebsiella pneumoniae (CR-Kp) has been largely associated with sequence type 258 (ST258) and its related variants…”
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In vitro selection of aztreonam/avibactam resistance in dual-carbapenemase-producing Klebsiella pneumoniae
Published in Journal of antimicrobial chemotherapy (01-03-2020)“…Abstract Objectives To examine the in vitro selection of aztreonam/avibactam resistance among MBL-producing Klebsiella pneumoniae and to understand the…”
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Complete Nucleotide Sequence of a blaKPC-Harboring IncI2 Plasmid and Its Dissemination in New Jersey and New York Hospitals
Published in Antimicrobial Agents and Chemotherapy (01-10-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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CG258 Klebsiella pneumoniae isolates without β-lactam resistance at the onset of the carbapenem-resistant Enterobacteriaceae epidemic in New York City
Published in Journal of antimicrobial chemotherapy (01-01-2019)“…Abstract Objectives To examine the epidemiology of β-lactam resistance in ‘clonal group 258’ (CG258), a successful KPC clonal group, over 14 years. Methods…”
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Complete Sequence of a KPC-Producing IncN Multidrug-Resistant Plasmid from an Epidemic Escherichia coli Sequence Type 131 Strain in China
Published in Antimicrobial agents and chemotherapy (01-04-2014)“…We report here the nucleotide sequence of a novel blaKPC-2-harboring incompatibility group N (IncN) plasmid, pECN580, from a multidrug-resistant Escherichia…”
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Colonization With Levofloxacin-resistant Extended-spectrum β-Lactamase-producing Enterobacteriaceae and Risk of Bacteremia in Hematopoietic Stem Cell Transplant Recipients
Published in Clinical infectious diseases (13-11-2018)“…Prior to transplant, 10% of hematopoietic stem cell transplant recipients were colonized with ESBL-producing Enterobacteriaceae (ESBL-E). In the setting of…”
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Comparative Genomic Analysis of KPC-Encoding pKpQIL-Like Plasmids and Their Distribution in New Jersey and New York Hospitals
Published in Antimicrobial agents and chemotherapy (01-05-2014)“…The global spread of Klebsiella pneumoniae carbapenemase (KPC) is predominately associated with K. pneumoniae strains genotyped as sequence type 258 (ST258)…”
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Piperacillin-Tazobactam-Resistant/Third-Generation Cephalosporin-Susceptible Escherichia coli and Klebsiella pneumoniae Isolates: Resistance Mechanisms and In vitro-In vivo Discordance
Published in International journal of antimicrobial agents (01-03-2020)“…•Bacteria can be resistant to piperacillin-tazobactam (TZP) but susceptible to cephalosporins (TZP-R/Ceph3-S)•TEM-1 hyperproduction causes in vitro TZP-R among…”
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Genomic Characterization of VIM Metallo-β-Lactamase-Producing Alcaligenes faecalis from Gaza, Palestine
Published in Antimicrobial agents and chemotherapy (01-11-2017)“…Carbapenemase-producing Gram-negative bacteria (CP-GNB) have increasingly spread worldwide, and different families of carbapenemases have been identified in…”
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