Search Results - "Chavas, Thomas E. J."

Biarylphosphonite Gold(I) Complexes as Superior Catalysts for Oxidative Cyclization of Propynyl Arenes into Indan-2-ones by Henrion, Guilhem, Chavas, Thomas E. J., Le Goff, Xavier, Gagosz, Fabien

“…Striking gold: A series of variously functionalized propynyl arenes was smoothly converted into indan‐2‐ones by a new gold(I)‐catalyzed oxidative cyclization…”
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Unbiased Mass Spectrometry Elucidation of the Targets and Mechanisms of Activity-Based Probes: A Case Study Involving Sulfonyl Fluorides by Chavas, Thomas E. J, Fuchter, Matthew J, DiMaggio, Peter A

“…The elucidation of protein/drug interactions remains a major challenge in drug discovery. Liquid chromatography–tandem mass spectrometry has emerged as a…”
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Fully synthetic injectable depots with high drug content and tunable pharmacokinetics for long-acting drug delivery by Ho, Duy-Khiet, LeGuyader, Clare, Srinivasan, Selvi, Roy, Debashish, Vlaskin, Vladimir, Chavas, Thomas E.J., Lopez, Ciana L., Snyder, Jessica M., Postma, Almar, Chiefari, John, Stayton, Patrick S.

“…Clinical studies have validated that antiretroviral (ARV) drugs can serve as an HIV pre-exposure prophylactic (PrEP) strategy. Dosing adherence remains a…”
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A macrophage-targeted platform for extending drug dosing with polymer prodrugs for pulmonary infection prophylaxis by Chavas, Thomas E.J., Su, Fang-Yi, Srinivasan, Selvi, Roy, Debashish, Lee, Brian, Lovelace-Macon, Lara, Rerolle, Guilhem F., Limqueco, Elaine, Skerrett, Shawn J., Ratner, Daniel M., West, T. Eoin, Stayton, Patrick S.

“…Pulmonary melioidosis is a bacterial disease with high morbidity and a mortality rate that can be as high as 40% in resource-poor regions of South Asia. This…”
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Liver-targeted polymeric prodrugs of 8-aminoquinolines for malaria radical cure by Srinivasan, Selvi, Roy, Debashish, Chavas, Thomas E.J., Vlaskin, Vladimir, Ho, Duy-Khiet, Pottenger, Ayumi, LeGuyader, Clare L.M., Maktabi, Mahdi, Strauch, Pamela, Jackson, Conner, Flaherty, Siobhan M., Lin, Hsiuling, Zhang, Jing, Pybus, Brandon, Li, Qigui, Huber, Hans E., Burke, Paul A., Wesche, David, Rochford, Rosemary, Stayton, Patrick S.

“…Primaquine and tafenoquine are the two 8-aminoquinoline (8-AQ) antimalarial drugs approved for malarial radical cure - the elimination of liver stage…”
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Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure by Pottenger, Ayumi E, Roy, Debashish, Srinivasan, Selvi, Chavas, Thomas E J, Vlaskin, Vladmir, Ho, Duy-Khiet, Livingston, Vincent C, Maktabi, Mahdi, Lin, Hsiuling, Zhang, Jing, Pybus, Brandon, Kudyba, Karl, Roth, Alison, Senter, Peter, Tyson, George, Huber, Hans E, Wesche, David, Rochford, Rosemary, Burke, Paul A, Stayton, Patrick S

“…Approximately 3.3 billion people live with the threat of malaria. Infection can result in liver-localized hypnozoites, which when reactivated cause relapsing…”
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Biarylphosphonite Gold(I) Complexes as Superior Catalysts for Oxidative Cyclization of Propynyl Arenes into Indan-2-ones by Henrion, Guilhem, Chavas, Thomas E. J., Le Goff, Xavier, Gagosz, Fabien

“…Erstaunliches Gold: Eine Serie funktionalisierter Propinylarene wurde durch einen neuen, milden Gold(I)‐katalysierten oxidativen Cyclisierungsprozess in…”
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