Search Results - "Chavan Ravindranath, Aakash"

Data-driven approaches used for compound library design, hit triage and bioactivity modeling in high-throughput screening by Paricharak, Shardul, Méndez-Lucio, Oscar, Chavan Ravindranath, Aakash, Bender, Andreas, IJzerman, Adriaan P, van Westen, Gerard J P

“…Abstract High-throughput screening (HTS) campaigns are routinely performed in pharmaceutical companies to explore activity profiles of chemical libraries for…”
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HitPickV2: a web server to predict targets of chemical compounds by Hamad, Sabri, Adornetto, Gianluca, Naveja, J Jesús, Chavan Ravindranath, Aakash, Raffler, Johannes, Campillos, Mónica

“…Abstract Motivation The identification of protein targets of novel compounds is essential to understand compounds' mechanisms of action leading to biological…”
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Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis by Ravindranath, Aakash Chavan, Perualila-Tan, Nolen, Kasim, Adetayo, Drakakis, Georgios, Liggi, Sonia, Brewerton, Suzanne C, Mason, Daniel, Bodkin, Michael J, Evans, David A, Bhagwat, Aditya, Talloen, Willem, Göhlmann, Hinrich W H, Shkedy, Ziv, Bender, Andreas

“…Integrating gene expression profiles with certain proteins can improve our understanding of the fundamental mechanisms in protein-ligand binding. This paper…”
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