Search Results - "Chavali, Venkata Ramana Murthy"
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1
Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium
Published in Journal of lipid research (01-10-2018)“…Cholesterol-containing soft drusen and subretinal drusenoid deposits (SDDs) occur at the basolateral and apical side of the retinal pigment epithelium (RPE),…”
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2
Transplanted human induced pluripotent stem cells- derived retinal ganglion cells embed within mouse retinas and are electrophysiologically functional
Published in iScience (18-11-2022)“…Glaucoma is an optic neuropathy characterized by permanent visual field loss caused by the death of retinal ganglion cells (RGCs) and it is the leading cause…”
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3
Rescue of retinal ganglion cells in optic nerve injury using cell-selective AAV mediated delivery of SIRT1
Published in Gene therapy (01-05-2021)“…SIRT1 prevents retinal ganglion cell (RGC) loss in models of optic neuropathy following pharmacologic activation or genetic overexpression. The exact mechanism…”
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Complete Transcriptome Profiling of Normal and Age-Related Macular Degeneration Eye Tissues Reveals Dysregulation of Anti-Sense Transcription
Published in Scientific reports (14-02-2018)“…Age-related macular degeneration (AMD) predominantly affects the retina and retinal pigment epithelium in the posterior eye. While there are numerous studies…”
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Long-Term Effects of Gene Therapy in a Novel Mouse Model of Human MFRP -Associated Retinopathy
Published in Human gene therapy (01-05-2019)“…Patients harboring homozygous c.498_499insC mutations in demonstrate hyperopia, microphthalmia, retinitis pigmentosa, retinal pigment epithelial atrophy,…”
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Evaluating TNF-α and Interleukin-2 (IL-2) Levels in African American Primary Open-Angle Glaucoma Patients
Published in Genes (25-12-2021)“…To establish if SNPs in and genes are associated with Primary Open-Angle Glaucoma (POAG) in African Americans (AA). We also determined whether plasma TNF-α and…”
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7
Association of OCT derived drusen measurements with AMD associated-genotypic SNPs in Amish population
Published in Journal of clinical medicine (12-02-2015)“…To investigate the association of OCT derived drusen measures in Amish age-related macular degeneration (AMD) patients with known loci for macular…”
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The Primary Open-Angle African American Glaucoma Genetics Study
Published in Ophthalmology (Rochester, Minn.) (01-04-2015)“…Purpose To describe the baseline characteristics of the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study cohort, the largest African…”
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Molecular cloning, sequence analysis and expression of genome segment 7 (S7) of Antheraea mylitta cypovirus (AmCPV) that encodes a viral structural protein
Published in Virus genes (01-10-2007)“…The Genome segment 7 (S7) of the 11 double stranded RNA genomes from Antheraea mylitta cypovirus (AmCPV) was converted to cDNA, cloned and sequenced. The…”
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10
The primary open-angle african american glaucoma genetics study: baseline demographics
Published in Ophthalmology (Rochester, Minn.) (01-04-2015)“…To describe the baseline characteristics of the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study cohort, the largest African American…”
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11
A missense mutation in ASRGL1 is involved in causing autosomal recessive retinal degeneration
Published in Human molecular genetics (15-06-2016)“…Inherited retinal dystrophies are a group of genetically heterogeneous conditions with broad phenotypic heterogeneity. We analyzed a large five-generation…”
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12
Risk Factors Associated with Progression to Blindness from Primary Open-Angle Glaucoma in an African-American Population
Published in Ophthalmic epidemiology (03-07-2016)“…Purpose: To determine the risk factors associated with progression to blindness from primary open-angle glaucoma (POAG) in an African-American population…”
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13
Analyzing the catalytic mechanism of MPtpA: A low molecular weight protein tyrosine phosphatase from Mycobacterium tuberculosis through site-directed mutagenesis
Published in Proteins, structure, function, and bioinformatics (01-05-2008)“…Mycobacterium tuberculosis adopts various measures to escape from the hostile environment of the host cells. A low molecular weight protein tyrosine…”
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14
Molecular characterization of genome segment 2 encoding RNA dependent RNA polymerase of Antheraea mylitta cytoplasmic polyhedrosis virus
Published in Virology (New York, N.Y.) (15-08-2010)“…Abstract Genome segment 2 (S2) from Antheraea mylitta cypovirus (AmCPV) was converted into cDNA, cloned and sequenced. S2 consisted of 3798 nucleotides with a…”
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Silencing the expression of CTRP5/C1QTNF5 and ELOVL4 genes by small interfering RNA
Published in Advances in experimental medicine and biology (2012)Get more information
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16
Molecular cloning and characterization of Antheraea mylitta cytoplasmic polyhedrosis virus polyhedrin gene and its variant forms
Published in Biochemical and biophysical research communications (08-07-2005)“…The segments 10 (S10) of the 11 double stranded RNA genomes from Antheraea mylitta cytoplasmic polyhedrosis virus (AmCPV) encoding a novel polyhedrin…”
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