Search Results - "Chauvierre, Cédric"

Nanomedicine progress in thrombolytic therapy by Zenych, Alina, Fournier, Louise, Chauvierre, Cédric

“…Thrombotic occlusions of blood vessels are responsible for life-threatening cardiovascular disorders such as myocardial infarction, ischemic stroke, and venous…”
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Microbubbles for human diagnosis and therapy by Fournier, Louise, de La Taille, Thibault, Chauvierre, Cédric

“…Microbubbles (MBs) were observed for the first time in vivo as a curious consequence of quick saline injection during ultrasound (US) imaging of the aortic…”
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Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs Carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots by Colasuonno, Marianna, Palange, Anna Lisa, Aid, Rachida, Ferreira, Miguel, Mollica, Hilaria, Palomba, Roberto, Emdin, Michele, Del Sette, Massimo, Chauvierre, Cédric, Letourneur, Didier, Decuzzi, Paolo

“…Tissue plasminogen activator (tPA) is the sole approved therapeutic molecule for the treatment of acute ischemic stroke. Yet, only a small percentage of…”
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Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin by Juenet, Maya, Aid-Launais, Rachida, Li, Bo, Berger, Alice, Aerts, Joël, Ollivier, Véronique, Nicoletti, Antonino, Letourneur, Didier, Chauvierre, Cédric

“…Injection of recombinant tissue plasminogen activator (rt-PA) is the standard drug treatment for thrombolysis. However, rt-PA shows risk of hemorrhages and…”
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Fucoidans in Nanomedicine by Chollet, Lucas, Saboural, Pierre, Chauvierre, Cédric, Villemin, Jean-Noël, Letourneur, Didier, Chaubet, Frédéric

“…Fucoidans are widespread cost-effective sulfated marine polysaccharides which have raised interest in the scientific community over last decades for their wide…”
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REVIEW: “ISCHEMIC STROKE: From Fibrinolysis to Functional Recovery” Nanomedicine: emerging approaches to treat ischemic stroke by Sarfati, Pierre, De La Taille, Thibault, Portioli, Corinne, Spanò, Raffaele, Lalatonne, Yoann, Decuzzi, Paolo, Chauvierre, Cédric

“…•Nanoparticles (NPs) are versatile agents to treat all phases of ischemic stroke.•Thrombolysis and neuroprotection can be tackled with nanotechnologies.•Many…”
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Combining magnetic nanoparticles with cell derived microvesicles for drug loading and targeting by Silva, Amanda K.A., PhD, Luciani, Nathalie, PhD, Gazeau, Florence, PhD, Aubertin, Kelly, PhD, Bonneau, Stéphanie, PhD, Chauvierre, Cédric, PhD, Letourneur, Didier, PhD, Wilhelm, Claire, PhD

“…Abstract Inspired by microvesicle-mediated intercellular communication, we propose a hybrid vector for magnetic drug delivery. It consists of…”
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rtPA-loaded fucoidan polymer microbubbles for the targeted treatment of stroke by Fournier, Louise, Abioui-Mourgues, Myriam, Chabouh, Georges, Aid, Rachida, Taille, Thibault De La, Couture, Olivier, Vivien, Denis, Orset, Cyrille, Chauvierre, Cédric

“…Systemic injection of thrombolytic drugs is the gold standard treatment for non-invasive blood clot resolution. The most serious risks associated with the…”
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Functionalized polymer microbubbles as new molecular ultrasound contrast agent to target P-selectin in thrombus by Li, Bo, Aid-Launais, Rachida, Labour, Marie-Noëlle, Zenych, Alina, Juenet, Maya, Choqueux, Christine, Ollivier, Véronique, Couture, Olivier, Letourneur, Didier, Chauvierre, Cédric

“…Thrombotic diseases rarely cause symptoms until advanced stage and sudden death. Thus, early detection of thrombus by a widely spread imaging modality can…”
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Fucoidan-functionalized polysaccharide submicroparticles loaded with alteplase for efficient targeted thrombolytic therapy by Zenych, Alina, Jacqmarcq, Charlène, Aid, Rachida, Fournier, Louise, Forero Ramirez, Laura M., Chaubet, Frédéric, Bonnard, Thomas, Vivien, Denis, Letourneur, Didier, Chauvierre, Cédric

“…Intravenous administration of fibrinolytic drugs is the standard treatment of acute thrombotic diseases. However, current fibrinolytics exhibit limited…”
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Polysaccharide nanosystems for future progress in cardiovascular pathologies by Silva, Amanda Karine Andriola, Letourneur, Didier, Chauvierre, Cédric

“…Natural polysaccharides have received a lot of attention in the biomedical field. Indeed, sources of polysaccharides, extracted or produced from plants,…”
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The European project NanoAthero to fight cardiovascular diseases using nanotechnologies by Chauvierre, Cédric, Letourneur, Didier

“…Cardiovascular diseases are the main causes of death in the world. Nanosystems with contrast agents or drugs appear as promising tools for early detection and…”
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From design to the clinic: practical guidelines for translating cardiovascular nanomedicine by Cicha, Iwona, Chauvierre, Cédric, Texier, Isabelle, Cabella, Claudia, Metselaar, Josbert M, Szebeni, János, Dézsi, László, Alexiou, Christoph, Rouzet, François, Storm, Gert, Stroes, Erik, Bruce, Donald, MacRitchie, Neil, Maffia, Pasquale, Letourneur, Didier

“…Abstract Cardiovascular diseases (CVD) account for nearly half of all deaths in Europe and almost 30% of global deaths. Despite the improved clinical…”
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Enabling MedTech Translation in Academia: Redefining Value Proposition with Updated Regulations by Letourneur, Didier, Joyce, Kieran, Chauvierre, Cédric, Bayon, Yves, Pandit, Abhay

“…Academic institutions are becoming more focused on translating new technologies for clinical applications. A transition from “bench to bedside” is often…”
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P-selectin targeting polysaccharide-based nanogels for miRNA delivery by Moraes, Fernanda C., Marcelo Forero Ramirez, Laura, Aid, Rachida, Benadda, Samira, Maire, Murielle, Chauvierre, Cédric, Antunes, Joana C., Chaubet, Frédéric, Letourneur, Didier

“…[Display omitted] Nanogels were prepared in aqueous media without the use of any organic solvent via a simple polyelectrolyte complexation method between…”
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Synthesis of cationic quaternized pullulan derivatives for miRNA delivery by Moraes, Fernanda C., Antunes, Joana C., Forero Ramirez, Laura Marcela, Aprile, Paola, Franck, Gregory, Chauvierre, Cédric, Chaubet, Frédéric, Letourneur, Didier

“…[Display omitted] Pullulan is a natural polysaccharide of potential interest for biomedical applications due to its non-toxic, non-immunogenic and…”
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Development of Polymer Microcapsules Functionalized with Fucoidan to Target P‐Selectin Overexpressed in Cardiovascular Diseases by Li, Bo, Juenet, Maya, Aid‐Launais, Rachida, Maire, Murielle, Ollivier, Véronique, Letourneur, Didier, Chauvierre, Cédric

“…New tools for molecular imaging and targeted therapy for cardiovascular diseases are still required. Herein, biodegradable microcapsules (MCs) made of…”
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Gd(DOTA)-grafted submicronic polysaccharide-based particles functionalized with fucoidan as potential MR contrast agent able to target human activated platelets by Forero Ramirez, Laura Marcela, Gobin, Elise, Aid-Launais, Rachida, Journe, Clément, Moraes, Fernanda C., Picton, Luc, Le Cerf, Didier, Letourneur, Didier, Chauvierre, Cédric, Chaubet, Frédéric

“…[Display omitted] •Polysaccharide matrix contained both fucoidan and dextran gadolinium macrocomplex.•A simple and green water-in-oil…”
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Enabling MedTech Translation in Academia: Redefining Value Proposition with Updated Regulations by Letourneur, Didier, Joyce, Kieran, Chauvierre, Cédric, Bayon, Yves, Pandit, Abhay

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Purification of a low molecular weight fucoidan for SPECT molecular imaging of myocardial infarction by Saboural, Pierre, Chaubet, Frédéric, Rouzet, Francois, Al-Shoukr, Faisal, Azzouna, Rana Ben, Bouchemal, Nadia, Picton, Luc, Louedec, Liliane, Maire, Murielle, Rolland, Lydia, Potier, Guy, Guludec, Dominique Le, Letourneur, Didier, Chauvierre, Cédric

“…Fucoidans constitute a large family of sulfated polysaccharides with several biochemical properties. A commercial fucoidan from brown algae, containing low…”
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