Search Results - "Chaurushiya, Mira S."

Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1 by He, Meng, Chaurushiya, Mira S, Webster, Joshua D, Kummerfeld, Sarah, Reja, Rohit, Chaudhuri, Subhra, Chen, Ying-Jiun, Modrusan, Zora, Haley, Benjamin, Dugger, Debra L, Eastham-Anderson, Jeffrey, Lau, Shari, Dey, Anwesha, Caothien, Roger, Roose-Girma, Merone, Newton, Kim, Dixit, Vishva M

“…Malignancies arising from mutation of tumor suppressors have unexplained tissue proclivity. For example, encodes a widely expressed deubiquitinase for histone…”
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The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0 by Lilley, Caroline E, Chaurushiya, Mira S, Boutell, Chris, Everett, Roger D, Weitzman, Matthew D

“…Cellular restriction factors responding to herpesvirus infection include the ND10 components PML, Sp100 and hDaxx. During the initial stages of HSV-1…”
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A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses by Lilley, Caroline E, Chaurushiya, Mira S, Boutell, Chris, Landry, Sebastien, Suh, Junghae, Panier, Stephanie, Everett, Roger D, Stewart, Grant S, Durocher, Daniel, Weitzman, Matthew D

“…The ICP0 protein of herpes simplex virus type 1 is an E3 ubiquitin ligase and transactivator required for the efficient switch between latent and lytic…”
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Genomes in Conflict: Maintaining Genome Integrity During Virus Infection by WEITZMAN, Matthew D, LILLEY, Caroline E, CHAURUSHIYA, Mira S

“…The cellular surveillance network for sensing and repairing damaged DNA prevents an array of human diseases, and when compromised it can lead to genomic…”
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Viral E3 Ubiquitin Ligase-Mediated Degradation of a Cellular E3: Viral Mimicry of a Cellular Phosphorylation Mark Targets the RNF8 FHA Domain by Chaurushiya, Mira S., Lilley, Caroline E., Aslanian, Aaron, Meisenhelder, Jill, Scott, Daniel C., Landry, Sébastien, Ticau, Simina, Boutell, Chris, Yates, John R., Schulman, Brenda A., Hunter, Tony, Weitzman, Matthew D.

“…Viral hijacking of cellular processes relies on the ability to mimic the structure or function of cellular proteins. Many viruses encode ubiquitin ligases to…”
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Chromatin at the intersection of viral infection and DNA damage by Lilley, Caroline E., Chaurushiya, Mira S., Weitzman, Matthew D.

“…During infection, viruses cause global disruption to nuclear architecture in their attempt to take over the cell. In turn, the host responds with various…”
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Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation by Dey, Anwesha, Seshasayee, Dhaya, Noubade, Rajkumar, French, Dorothy M., Liu, Jinfeng, Chaurushiya, Mira S., Kirkpatrick, Donald S., Pham, Victoria C., Lill, Jennie R., Bakalarski, Corey E., Wu, Jiansheng, Phu, Lilian, Katavolos, Paula, LaFave, Lindsay M., Abdel-Wahab, Omar, Modrusan, Zora, Seshagiri, Somasekar, Dong, Ken, Lin, Zhonghua, Balazs, Mercedesz, Suriben, Rowena, Newton, Kim, Hymowitz, Sarah, Garcia-Manero, Guillermo, Martin, Flavius, Levine, Ross L., Dixit, Vishva M.

“…De-ubiquitinating enzyme BAP1 is mutated in a hereditary cancer syndrome with increased risk of mesothelioma and uveal melanoma. Somatic BAP1 mutations occur…”
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Viral manipulation of DNA repair and cell cycle checkpoints by Chaurushiya, Mira S., Weitzman, Matthew D.

“…Recognition and repair of DNA damage is critical for maintaining genomic integrity and suppressing tumorigenesis. In eukaryotic cells, the sensing and repair…”
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The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma by Webster, Joshua D., Pham, Trang H., Wu, Xiumin, Hughes, Nicolas W., Li, Zhongwu, Totpal, Klara, Lee, Ho‐June, Calses, Philamer C., Chaurushiya, Mira S., Stawiski, Eric W., Modrusan, Zora, Chang, Matthew T., Tran, Christopher, Lee, Wyne P., Chalasani, Sreedevi, Hung, Jeffrey, Sharma, Neeraj, Chan, Sara, Hotzel, Kathy, Talevich, Eric, Shain, Alan, Xu, Mengshu, Lill, Jennie, Dixit, Vishva M., Bastian, Boris C., Dey, Anwesha

“…The deubiquitinating enzyme BAP1 is mutated in a hereditary cancer syndrome with a high risk of mesothelioma and melanocytic tumors. Here, we show that Bap1…”
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Changing the ubiquitin landscape during viral manipulation of the DNA damage response by Weitzman, Matthew D., Lilley, Caroline E., Chaurushiya, Mira S.

“…Viruses often induce signaling through the same cellular cascades that are activated by damage to the cellular genome. Signaling triggered by viral proteins or…”
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The tumor suppressor BAP 1 cooperates with BRAFV 600E to promote tumor formation in cutaneous melanoma by Webster, Joshua D., Pham, Trang H., Wu, Xiumin, Hughes, Nicolas W., Li, Zhongwu, Totpal, Klara, Lee, Ho‐June, Calses, Philamer C., Chaurushiya, Mira S., Stawiski, Eric W., Modrusan, Zora, Chang, Matthew T., Tran, Christopher, Lee, Wyne P., Chalasani, Sreedevi, Hung, Jeffrey, Sharma, Neeraj, Chan, Sara, Hotzel, Kathy, Talevich, Eric, Shain, Alan, Xu, Mengshu, Lill, Jennie, Dixit, Vishva M., Bastian, Boris C., Dey, Anwesha

“…The deubiquitinating enzyme BAP 1 is mutated in a hereditary cancer syndrome with a high risk of mesothelioma and melanocytic tumors. Here, we show that Bap1…”
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Viral manipulation of DNA repair and cell cycle checkpoints: Checkpoint response to DNA damage by CHAURUSHIYA, Mira S, WEITZMAN, Matthew D

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The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICPO by Lilley, Caroline E, Chaurushiya, Mira S, Boutell, Chris, Everett, Roger D, Weitzman, Matthew D

“…Cellular restriction factors responding to herpesvirus infection include the ND10 components PML, Sp100 and hDaxx. During the initial stages of HSV-1…”
Get full text