Search Results - "Chauhan, Sudhir Kumar"
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1
RNA-seq Analysis Reveals Unique Transcriptome Signatures in Systemic Lupus Erythematosus Patients with Distinct Autoantibody Specificities
Published in PloS one (11-11-2016)“…Systemic lupus erythematosus (SLE) patients exhibit immense heterogeneity which is challenging from the diagnostic perspective. Emerging high throughput…”
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2
A Simple Heuristic Approach for Step Fixed Charge Bulk Transportation Problem
Published in International journal of mathematical, engineering and management sciences (01-12-2024)“…The classical transportation problem (CTP) is a particular kind of optimization problem. It involves determining the most cost-effective way to transport a…”
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3
Effect of MHD on Unsteady Oscillatory Couette Flow Through Porous Media
Published in International Journal of Applied Mechanics and Engineering (01-03-2022)“…This paper describes the effects of a magnetic field on unsteady free convection oscillatory systems. When temperature and species concentration fluctuate with…”
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4
Peripheral immune cells in metastatic breast cancer patients display a systemic immunosuppressed signature consistent with chronic inflammation
Published in NPJ breast cancer (23-04-2024)“…Immunotherapies blocking the PD-1/PD-L1 checkpoint show some efficacy in metastatic breast cancer (mBC) but are often hindered by immunosuppressive mechanisms…”
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5
Decreased Toll-Like Receptor-4/Myeloid Differentiation Factor 88 Response Leads to Defective Interleukin-1β Production in Term Low Birth Weight Newborns
Published in The Pediatric infectious disease journal (01-12-2014)“…BACKGROUND:Morbidity and mortality rates are very high in low birth weight (LBW) newborns because of their increased susceptibility to infections compared with…”
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6
Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial
Published in Journal for immunotherapy of cancer (19-01-2024)“…BackgroundImmune checkpoint inhibitors have shown minimal clinical activity in hormone receptor-positive metastatic breast cancer (HR+mBC). Doxorubicin and…”
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7
Prevalence and Association of Mycobacterium avium subspecies paratuberculosis with Disease Course in Patients with Ulcero-Constrictive Ileocolonic Disease
Published in PloS one (28-03-2016)“…Association of Mycobacterium avium subspecies paratuberculosis (MAP) and Crohn's disease (CD) has been controversial due to contradictory reports. Therefore,…”
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8
Decreased pattern recognition receptor signaling, interferon-signature, and bactericidal/permeability-increasing protein gene expression in cord blood of term low birth weight human newborns
Published in PloS one (23-04-2013)“…Morbidity and mortality rates of low birth weight (LBW) newborns at term are higher than rates in normal birth weight (NBW) newborns. LBW newborns are at…”
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9
Resident memory CD8 T cells persist for years in human small intestine
Published in The Journal of experimental medicine (07-10-2019)“…Resident memory CD8 T (Trm) cells have been shown to provide effective protective responses in the small intestine (SI) in mice. A better understanding of the…”
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10
Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial
Published in Nature medicine (01-12-2022)“…Immune checkpoint inhibitors have shown efficacy against metastatic triple-negative breast cancer (mTNBC) but only for PD-L1 positive disease. The randomized,…”
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11
Distinct Autoantibody Profiles in Systemic Lupus Erythematosus Patients are Selectively Associated with TLR7 and TLR9 Upregulation
Published in Journal of clinical immunology (01-07-2013)“…Purpose Systemic lupus erythematosus (SLE) patients have a wide array of autoantibodies against nuclear antigens. The two predominant classes of these…”
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12
CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile
Published in Mucosal immunology (01-03-2021)“…Studies in mice and humans have shown that CD8 + T cell immunosurveillance in non-lymphoid tissues is dominated by resident populations. Whether CD4 + T cells…”
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13
Differential microRNA Profile and Post-Transcriptional Regulation Exist in Systemic Lupus Erythematosus Patients with Distinct Autoantibody Specificities
Published in Journal of clinical immunology (01-05-2014)“…Purpose Systemic lupus erythematosus (SLE) patients have anti-nuclear autoantibodies directed against dsDNA and RNA-associated antigens (extractable nuclear…”
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14
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
Published in Journal of allergy and clinical immunology (01-07-2023)“…Regulatory T (Treg) CD4 cells in mouse gut are mainly specific for intestinal antigens and play an important role in the suppression of immune responses…”
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15
Differential clearance mechanisms, neutrophil extracellular trap degradation and phagocytosis, are operative in systemic lupus erythematosus patients with distinct autoantibody specificities
Published in Immunology letters (01-12-2015)“…Highlights • Varying clearance mechanisms are operative in anti-dsDNA+ and anti-ENA+ SLE patients. • NET-degradation is specifically impaired in patients with…”
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16
Heat shock protein 27 and its regulatory molecules express differentially in SLE patients with distinct autoantibody profiles
Published in Immunology letters (01-03-2015)“…Highlights • Downregulation of HSP27 specifically in anti-ENA+ SLE patients. • HSP27 expression correlated inversely with caspase 3 and PARP expression. •…”
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17
CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile
Published in Mucosal immunology (2020)“…Studies in mice and humans have shown that CD8+ T cell immunosurveillance in non-lymphoid tissues is dominated by resident populations. Whether CD4+ T cells…”
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Journal Article -
18
CD4 + T cells persist for years in the human small intestine and display a T H 1 cytokine profile
Published in Mucosal immunology (01-03-2021)“…Studies in mice and humans have shown that CD8 T cell immunosurveillance in non-lymphoid tissues is dominated by resident populations. Whether CD4 T cells use…”
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Journal Article -
19
Effect of Credit Financing on the Supply Chain for Imperfect Deteriorating Items with Carbon Emission
Published in 2024 11th International Conference on Reliability, Infocom Technologies and Optimization (Trends and Future Directions) (ICRITO) (14-03-2024)“…The sustainable inventory model is a framework designed to ensure manufacturing processes' sustainability while maintaining profitability. During…”
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Conference Proceeding -
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Efficient Solution for Bi-Criteria Multi-Index Bulk Transportation Problem
Published in 2021 9th International Conference on Reliability, Infocom Technologies and Optimization (Trends and Future Directions) (ICRITO) (03-09-2021)“…In the work present, we have considered bicriteria multi-index bulk transportation problem (BCMIBTP). A multi-index bulk transportation problem (MIBTP) is an…”
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Conference Proceeding