Search Results - "Chauhan, Pradeep S."
-
1
Urine tumor DNA detection of minimal residual disease in muscle-invasive bladder cancer treated with curative-intent radical cystectomy: A cohort study
Published in PLoS medicine (31-08-2021)“…The standard of care treatment for muscle-invasive bladder cancer (MIBC) is radical cystectomy, which is typically preceded by neoadjuvant chemotherapy…”
Get full text
Journal Article -
2
Optofluidic control of rodent learning using cloaked caged glutamate
Published in Proceedings of the National Academy of Sciences - PNAS (24-03-2020)“…Glutamate is the major excitatory neurotransmitter in the brain, and photochemical release of glutamate (or uncaging) is a chemical technique widely used by…”
Get full text
Journal Article -
3
Circulating tumor DNA based minimal residual disease detection and adjuvant treatment decision-making for muscle-invasive bladder cancer guided by modern clinical trials
Published in Translational oncology (01-11-2023)“…Up to 430,000 cases of bladder cancer are diagnosed each year worldwide. A proposed method for non-invasive monitoring has been to utilize a “liquid biopsy.”…”
Get full text
Journal Article -
4
Genomic approaches to cancer and minimal residual disease detection using circulating tumor DNA
Published in Journal for immunotherapy of cancer (01-06-2023)“…Liquid biopsies using cell-free circulating tumor DNA (ctDNA) are being used frequently in both research and clinical settings. ctDNA can be used to identify…”
Get full text
Journal Article -
5
Convergent Approach to the Tetracyclic Core of the Apparicine Class of Indole Alkaloids via a Key Intermolecular Nitrosoalkene Conjugate Addition
Published in Journal of organic chemistry (03-07-2014)“…Readily available methyl 3-formylindol-2-ylacetate and N-tosyl-4-chloro-3-piperidone oxime have been used to construct the tetracyclic skeleton of the…”
Get full text
Journal Article -
6
Urine cell-free DNA multi-omics to detect MRD and predict survival in bladder cancer patients
Published in NPJ precision oncology (19-01-2023)“…Circulating tumor DNA (ctDNA) sensitivity remains subpar for molecular residual disease (MRD) detection in bladder cancer patients. To remedy this problem, we…”
Get full text
Journal Article -
7
5‑Substituted N‑Aminoimidazolone Peptide Mimic Synthesis by Organocatalyzed Reactions of Azopeptides and Use in the Analysis of Biologically Active Backbone and Side-Chain Topology
Published in Organic letters (07-05-2021)“…Fifteen N-aminoimidazolone (Nai) dipeptides having a variety of 5-position side-chain groups were synthesized by regioselective proline-catalyzed reactions of…”
Get full text
Journal Article -
8
Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers
Published in Proceedings of the National Academy of Sciences - PNAS (06-12-2022)“…Transient soluble oligomers of amyloid-β (Aβ) are toxic and accumulate early prior to insoluble plaque formation and cognitive impairment in Alzheimer's…”
Get full text
Journal Article -
9
Emerging Roles of Circulating Tumor DNA for Increased Precision and Personalization in Radiation Oncology
Published in Seminars in radiation oncology (01-07-2023)“…Recent breakthroughs in circulating tumor DNA (ctDNA) technologies present a compelling opportunity to combine this emerging liquid biopsy approach with the…”
Get full text
Journal Article -
10
Aza-Residue Modulation of Cyclic d,l‑α-Peptide Nanotube Assembly with Enhanced Anti-Amyloidogenic Activity
Published in Journal of medicinal chemistry (23-02-2023)“…Transient soluble oligomers of amyloid-β (Aβ) are considered among the most toxic species in Alzheimer’s disease (AD). Soluble Aβ oligomers accumulate early…”
Get full text
Journal Article -
11
PACT: a pipeline for analysis of circulating tumor DNA
Published in Bioinformatics (Oxford, England) (01-08-2023)“…Abstract Motivation Detection of genomic alterations in circulating tumor DNA (ctDNA) is currently used for active clinical monitoring of cancer progression…”
Get full text
Journal Article -
12
Genomic and epigenomic analysis of plasma cell-free DNA identifies stemness features associated with worse survival in lethal prostate cancer
Published in Clinical cancer research (23-08-2024)“…Metastatic castration-resistant prostate cancer (mCRPC) resistant to androgen receptor signaling inhibitors (ARSIs) is often lethal. Liquid biopsy biomarkers…”
Get full text
Journal Article -
13
Commercial ctDNA Assays for Minimal Residual Disease Detection of Solid Tumors
Published in Molecular diagnosis & therapy (01-11-2021)“…The detection of circulating tumor DNA via liquid biopsy has become an important diagnostic test for patients with cancer. While certain commercial liquid…”
Get full text
Journal Article -
14
Economic Efficiency Measurement of Power Sector Reforms in Haryana Using DEA
Published in Indian economic journal (01-06-2020)“…Haryana power sector reforms were initiated as a part of the overall power sector reform process initiated in the country under the supervision of the World…”
Get full text
Journal Article -
15
Synthesis of the Tetracyclic Skeleton of the Lycopodium Alkaloid Lycopladine H via a Pivotal Double Hydroformylation/Intramolecular Reductive Amination Sequence
Published in Organic letters (20-02-2015)“…A synthesis of the complete tetracyclic framework of the structurally unique Lycopodium alkaloid lycopladine H has been accomplished using a strategy involving…”
Get full text
Journal Article -
16
Correction: Urine tumor DNA detection of minimal residual disease in muscle-invasive bladder cancer treated with curative-intent radical cystectomy: A cohort study
Published in PLoS medicine (14-12-2021)“…[This corrects the article DOI: 10.1371/journal.pmed.1003732.]…”
Get full text
Journal Article -
17
Synthesis and Evaluation of a Library of Fluorescent Dipeptidomimetic Analogues as Substrates for Modified Bacterial Ribosomes
Published in Biochemistry (Easton) (03-05-2016)“…Described herein are the synthesis and photophysical characterization of a library of aryl-substituted oxazole- and thiazole-based dipeptidomimetic analogues,…”
Get full text
Journal Article -
18
Hydrazine derivative synthesis by trifluoroacetyl hydrazide alkylation
Published in Canadian journal of chemistry (2020)“…N′-Alkyl hydrazides were effectively synthesized by routes featuring installation, alkylation, and removal of a trifluoroacetyl group. A set of amino acid…”
Get full text
Journal Article -
19
Urinary Tumor DNA-Based Diagnosis and Surveillance for Nonmuscle-Invasive Bladder Cancer—Current Landscape and Future Directions
Published in Société internationale d'urologie journal (14-07-2023)“…Bladder cancer has a significant impact on patients, in terms of both morbidity and financial burden. This is especially true for patients with…”
Get full text
Journal Article -
20
Aza‐propargylglycine installation by aza‐amino acylation: Synthesis and Ala‐scan of an azacyclopeptide CD36 modulator
Published in Peptide science (Hoboken, N.J.) (01-01-2019)“…Aza‐propargylglycine (azaPra) peptides are branching points for the synthesis of azapeptide libraries. Efficient alkylation of N‐(Fmoc)hydrazine in solution…”
Get full text
Journal Article