Search Results - "Chauhan, Ganesh"
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Genetic Risk Factors for Ischemic and Hemorrhagic Stroke
Published in Current cardiology reports (01-12-2016)“…Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel…”
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Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable
Published in Stroke (1970) (01-02-2018)“…BACKGROUND AND PURPOSE—The genetic contribution to dilated perivascular space (dPVS) burden—an emerging MRI marker of cerebral small vessel disease—is unknown…”
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Genome-Wide Association Study for Type 2 Diabetes in Indians Identifies a New Susceptibility Locus at 2q21
Published in Diabetes (New York, N.Y.) (01-03-2013)“…Indians undergoing socioeconomic and lifestyle transitions will be maximally affected by epidemic of type 2 diabetes (T2D). We conducted a two-stage…”
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Procalcitonin as a predictive marker in COVID-19: A systematic review and meta-analysis
Published in PloS one (09-09-2022)“…Coronavirus disease 2019 has emerged as a global pandemic causing millions of critical cases and deaths. Early identification of at-risk patients is crucial…”
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Outcome associated with use of winged expandable titanium cage following cervical corpectomy: an institutional experience
Published in Egyptian journal of neurosurgery (01-12-2024)“…Background In patients with spinal cord compression behind the cervical vertebra who presented with myelopathy, one of the treatment modalities is anterior…”
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Impact of Common Variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the Risk of Type 2 Diabetes in 5,164 Indians
Published in Diabetes (New York, N.Y.) (01-08-2010)“…Common variants in PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 genes have been shown to be associated with type 2 diabetes in European…”
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Mendelian Randomization and Bayesian Colocalization Analysis Implicate Glycoprotein VI as a Potential Drug Target for Cardioembolic Stroke in South Asian Populations
Published in Journal of the American Heart Association (20-08-2024)“…Circulating plasma proteins are clinically useful biomarkers for stroke risk. We examined the causal links between plasma proteins and stroke risk in…”
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Body Mass Index and Hypertension as Mediators of the Association Between Age at Menarche and Subclinical Atherosclerosis: A Sex-Specific Mendelian Randomization Analysis
Published in Journal of the American Heart Association (16-07-2024)“…Early age at menarche (AAM) has been associated with a higher risk of carotid artery intima-media thickness (cIMT), an indicator of subclinical vascular…”
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Common variants of FTO and the risk of obesity and type 2 diabetes in Indians
Published in Journal of human genetics (01-10-2011)“…Common variants of fat mass and obesity-associated gene (FTO, fat mass- and obesity-associated gene) have been shown to be associated with obesity and type 2…”
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Complications of Different Types of Cranioplasty and Identification of Risk Factors Associated with Cranioplasty at a Tertiary Care Centre: A Prospective Observational Study
Published in Indian journal of neurosurgery (01-03-2024)“…Abstract Objective Decompressive craniectomy (DC) is an urgent procedure which is done to decrease intracranial pressure. A study of the complications would…”
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Prospective Observational Study of Early Tracheostomy Role in Operated Severe Head Injury Patients at A Level 1 Trauma Center
Published in Bulletin of emergency & trauma (01-10-2021)“…To evaluate the impact of the early tracheostomy on operated patients with severe head injury. This prospective observational study was conducted at a level 1…”
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Common variants of FTO are associated with childhood obesity in a cross-sectional study of 3,126 urban Indian children
Published in PloS one (16-10-2012)“…FTO variants are robustly associated with obesity and related traits in many population and shown to have variable impact during life course. Although studies…”
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Strong influence of variants near MC4R on adiposity in children and adults: a cross-sectional study in Indian population
Published in Journal of human genetics (01-01-2013)“…Common variants near melanocortin 4 receptor (MC4R) gene are shown to be associated with adiposity but have varied effects in different age groups. Among…”
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Association of variants in genes involved in pancreatic β-cell development and function with type 2 diabetes in North Indians
Published in Journal of human genetics (01-10-2011)“…Variants in genes involved in pancreatic β-cell development and function are known to cause monogenic forms of type 2 diabetes and are also associated with…”
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Genetic variant of AMD1 is associated with obesity in urban Indian children
Published in PloS one (09-04-2012)“…Hyperhomocysteinemia is regarded as a risk factor for cardiovascular diseases, diabetes and obesity. Manifestation of these chronic metabolic disorders starts…”
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Common variants in CRP and LEPR influence high sensitivity C-reactive protein levels in North Indians
Published in PloS one (08-09-2011)“…High sensitivity C-reactive protein (hsCRP) levels are shown to be influenced by genetic variants in Europeans; however, little is explored in Indian…”
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Common variants of SLAMF1 and ITLN1 on 1q21 are associated with type 2 diabetes in Indian population
Published in Journal of human genetics (01-03-2012)“…Though multiple studies link chromosomal regions 1q21-q23 and 20q13 with type 2 diabetes, fine mapping of these regions is yet to confirm gene(s) explaining…”
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Evaluation of DOK5 as a susceptibility gene for type 2 diabetes and obesity in North Indian population
Published in BMC medical genetics (27-02-2010)“…Type 2 diabetes is a complex metabolic disorder with obesity being a major contributing factor in its development. Susceptibility loci for type 2 diabetes and…”
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No association of TNFRSF1B variants with type 2 diabetes in Indians of Indo-European origin
Published in BMC medical genetics (17-08-2011)“…There has been no systematic evaluation of the association between genetic variants of type 2 receptor for TNFα (TNFR2) and type 2 diabetes, despite strong…”
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Genetic Variants Associated with the Risk of Stroke in Sickle Cell Anemia: Systematic Review and Meta-Analysis
Published in Hemoglobin (03-03-2024)“…Sickle cell anemia (SCA) is the most common cause of stroke in children. As it is a rare disease, studies investigating the association with complications like…”
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