Search Results - "Chaugule, Sachin"

Sensors in Bone: Technologies, Applications, and Future Directions by Anwar, Afreen, Kaur, Taruneet, Chaugule, Sachin, Yang, Yeon-Suk, Mago, Aryan, Shim, Jae-Hyuck, John, Aijaz Ahmad

“…Osteoporosis, a prevalent ailment worldwide, compromises bone strength and resilience, particularly afflicting the elderly population. This condition…”
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Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery by Yang, Yeon-Suk, Kim, Jung-Min, Xie, Jun, Chaugule, Sachin, Lin, Chujiao, Ma, Hong, Hsiao, Edward, Hong, Jaehyoung, Chun, Hyonho, Shore, Eileen M., Kaplan, Frederick S., Gao, Guangping, Shim, Jae-Hyuck

“…Heterotopic ossification is the most disabling feature of fibrodysplasia ossificans progressiva, an ultra-rare genetic disorder for which there is currently no…”
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Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration by Lin, Chujiao, Yang, Qiyuan, Guo, Dongsheng, Xie, Jun, Yang, Yeon-Suk, Chaugule, Sachin, DeSouza, Ngoc, Oh, Won-Taek, Li, Rui, Chen, Zhihao, John, Aijaz A., Qiu, Qiang, Zhu, Lihua Julie, Greenblatt, Matthew B., Ghosh, Sankar, Li, Shaoguang, Gao, Guangping, Haynes, Cole, Emerson, Charles P., Shim, Jae-Hyuck

“…Although skeletal progenitors provide a reservoir for bone-forming osteoblasts, the major energy source for their osteogenesis remains unclear. Here, we…”
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AAV-based gene editing of type 1 collagen mutation to treat osteogenesis imperfecta by Yang, Yeon-Suk, Sato, Tadatoshi, Chaugule, Sachin, Ma, Hong, Xie, Jun, Gao, Guangping, Shim, Jae-Hyuck

“…Osteogenesis imperfecta (OI) is a genetic disorder characterized by bone fragility, low bone mass, fractures, and extraskeletal manifestations. Since OI is…”
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Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway by Kim, Jung-Min, Yang, Yeon-Suk, Hong, Jaehyoung, Chaugule, Sachin, Chun, Hyonho, van der Meulen, Marjolein C H, Xu, Ren, Greenblatt, Matthew B, Shim, Jae-Hyuck

“…Emerging evidence supports that osteogenic differentiation of skeletal progenitors is a key determinant of overall bone formation and bone mass. Despite…”
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Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling by Chaugule, Sachin, Kim, Jung-Min, Yang, Yeon-Suk, Knobeloch, Klaus-Peter, He, Xi, Shim, Jae-Hyuck

“…Disturbance in a differentiation program of skeletal stem cells leads to indecorous skeletogenesis. Growing evidence suggests that a fine-tuning of…”
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Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy by Yang, Yeon-Suk, Xie, Jun, Chaugule, Sachin, Wang, Dan, Kim, Jung-Min, Kim, JiHea, Tai, Phillip W.L., Seo, Seok-kyo, Gravallese, Ellen, Gao, Guangping, Shim, Jae-Hyuck

“…Improper activity of bone-resorbing osteoclasts results in low bone density and deterioration of bone structure, which increase the risk of fractures…”
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Methanolic extract of Euchelus asper exhibits in-ovo anti-angiogenic and in vitro anti-proliferative activities by Agrawal, Sweta, Chaugule, Sachin, More, Shashank, Rane, Gargi, Indap, Madhavi

“…The marine environment is a rich source of bioactive natural products. Many of the marine bioactive compounds have been derived successfully from molluscs…”
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Marine Natural Products: New Avenue in Treatment of Osteoporosis by Chaugule, Sachin R., Indap, Madhavi M., Chiplunkar, Shubhada V.

“…Bone metabolism is a physiological process that maintains the skeletal integrity and bone functions. Skeletal integrity is always balanced by two key cell…”
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Hexane Fraction of Turbo brunneus Inhibits Intermediates of RANK-RANKL Signaling Pathway and Prevent Ovariectomy Induced Bone Loss by Chaugule, Sachin, Kashipathi Sureshbabu, Shalini, Dakave, Suresh, Krishna, C. Murali, Chaudhari, Pradip, Indap, Madhavi, Chiplunkar, Shubhada

“…Osteoporosis is a “silent disease” characterized by fragile and impaired bone quality. Bone fracture results in increased mortality and poor quality of life in…”
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Advances in Bone-Targeting Drug Delivery: Emerging Strategies Using Adeno-Associated Virus by Sato, Tadatoshi, Chaugule, Sachin, Greenblatt, Matthew B, Gao, Guangping, Shim, Jae-Hyuck

“…The development of bone-targeting drug delivery systems holds immense promise for improving the treatment of skeletal diseases. By precisely delivering…”
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Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis by Stavre, Zheni, Kim, Jung-Min, Yang, Yeon-Suk, Nündel, Kerstin, Chaugule, Sachin, Sato, Tadatoshi, Park, Kwang Hwan, Gao, Guangping, Gravallese, Ellen M, Shim, Jae-Hyuck

“…Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to systemic and articular bone loss by activating bone resorption and suppressing bone…”
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WDM and optical amplifier (Wavelength Division Multiplexing) by Chaugule, Sachin, More, Ashish

“…Wavelength Division Multiplexing (WDM) is the basic technology of optical networking. It is a technique for using a fibre (or optical device) to carry many…”
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