Search Results - "Chaudhuri, T R"

Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus by KANERVA, A, ZINN, K. R, ALFTHAN, H, STENMAN, U.-H, CURIEL, D. T, HEMMINKI, A, PENG, K.-W, RANKI, T, KANGASNIEMI, L, CHAUDHURI, T. R, DESMOND, R. A, WANG, M, TAKAYAMA, K, HAKKARAINEN, T

“…In clinical trials with cancer patients, the safety of conditionally replicating adenoviruses (CRAds) has been good. However, marginal data are available on…”
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Bioluminescence imaging reveals a significant role for complement in liver transduction following intravenous delivery of adenovirus by ZINN, K. R, SZALAI, A. J, STARGEL, A, KRASNYKH, V, CHAUDHURI, T. R

“…The effect of complement on transgene expression was evaluated in vivo and in vitro using mice lacking complement components. Complement component 3 (C3)…”
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Non-invasive gamma camera imaging of gene transfer using an adenoviral vector encoding an epitope-tagged receptor as a reporter by ROGERS, B. E, CHAUDHURI, T. R, REYNOLDS, P. N, DELLA MANNA, D, ZINN, K. R

“…A model epitope-tagged receptor was constructed by fusing the hemagglutinin (HA) sequence on the extracellular N-terminus of the human somatostatin receptor…”
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Detection and measurement of in vitro gene transfer by gamma camera imaging by ZINN, K. R, CHAUDHURI, T. R, BUCHSBAUM, D. J, MOUNTZ, J. M, ROGERS, B. E

“…The purpose of this work was to develop a high capacity method to image gene transfer to cancer cells growing as monolayers in cell culture plates. A sensitive…”
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A Noninvasive Reporter System to Image Adenoviral-Mediated Gene Transfer to Ovarian Cancer Xenografts by Chaudhuri, Tandra R., Rogers, Buck E., Buchsbaum, Donald J., Mountz, James M., Zinn, Kurt R.

“…Objective. Gene therapy trials for ovarian cancer would benefit from a noninvasive imaging modality to detect the location and extent of gene transfer. The…”
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Imaging Tc-99m-labeled FGF-1 targeting in rats by Zinn, Kurt R, Kelpke, Stacey, Chaudhuri, Tandra R, Sugg, Tom, Mountz, James M, Thompson, John A

“…Recombinant human acidic fibroblast growth factor (FGF-1) was radiolabeled with 99mTc by the HYNIC method. The 99mTc-FGF-1 retained its representative…”
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An Adenovirus with Enhanced Infectivity Mediates Molecular Chemotherapy of Ovarian Cancer Cells and Allows Imaging of Gene Expression by Hemminki, Akseli, Belousova, Natalya, Zinn, Kurt R., Liu, Bin, Wang, Minghui, Chaudhuri, Tandra R., Rogers, Buck E., Buchsbaum, Donald J., Siegal, Gene P., Barnes, Mack N., Gomez-Navarro, Jesus, Curiel, David T., Alvarez, Ronald D.

“…The adenovirus (Ad) is a useful vector for cancer gene therapy due to its unparalleled gene transfer efficiency to dividing and quiescent cells. Primary cancer…”
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Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus by Kanerva, Anna, Zinn, Kurt R, Chaudhuri, Tandra R, Lam, John T, Suzuki, Kaori, Uil, Taco G, Hakkarainen, Tanja, Bauerschmitz, Gerd J, Wang, Minghui, Liu, Bin, Cao, Zhihong, Alvarez, Ronald D, Curiel, David T, Hemminki, Akseli

“…Oncolytic viruses that are replication competent in tumor but not in normal cells represent a novel approach for treating neoplastic diseases. However, the…”
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Light-Based Imaging of Green Fluorescent Protein-Positive Ovarian Cancer Xenografts during Therapy by Chaudhuri, Tandra R., Mountz, James M., Rogers, Buck E., Partridge, Edward E., Zinn, Kurt R.

“…Objective. The purpose of the study was to develop a sensitive, noninvasive imaging method for monitoring ovarian xenografts during therapeutic intervention…”
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Human monoclonal antibody developed against ovarian cancer cell surface antigen by Chaudhuri, T R, Zinn, K R, Morris, J S, McDonald, G A, Llorens, A S, Chaudhuri, T K

“…Murine monoclonal antibodies (MoAb) potentially can be used in the radioimmunodetection and radioimmunotherapy of cancer. However, the administration of these…”
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Noninvasive Monitoring of Gene Transfer Using a Reporter Receptor Imaged with a High-Affinity Peptide Radiolabeled with 99mTc or 188Re by Zinn, Kurt R, Buchsbaum, Donald J, Chaudhuri, Tandra R, Mountz, James M, Grizzle, William E, Rogers, Buck E

“…Gene therapy protocols require better modalities to monitor the location and level of transferred gene expression. One potential in vivo mechanism to assess…”
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Simultaneous evaluation of dual gene transfer to adherent cells by gamma-ray imaging by Zinn, Kurt R, Chaudhuri, Tandra R, Buchsbaum, Donald J, Mountz, James M, Rogers, Buck E

“…A gamma camera imaging method was developed to detect dual gene transfer to adherent cells growing as monolayers in cell culture plates. Human cancer cells…”
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Glomerular targeting of acidic fibroblast growth factor-1 in renal transplanted rats by ZINN, Kurt R, KELPKE, Stacey, AKHI, Kabir, VIERA, Liliana, CHAUDHURI, Tandra R, THOMPSON, John A

“…Acidic fibroblast growth factor (FGF-1) functions as a potent hormonal inducer of wound repair mechanisms in vivo. In addition, the involvement of FGF-1 in a…”
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59Fe is retained from an elemental 59Fe powder supplement without effects on 65Zinc, 47Calcium and 67Copper in young pigs by Zinn, K R, Chaudhuri, T R, Mountz, J M, van den Berg, G J, Gordon, D T, Johanning, G L

“…In vivo counting with the use of a germanium detector evaluated the retention of an elemental 59Fe powder supplement while measuring potential interactions…”
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Noninvasive Bioluminescence Imaging in Small Animals by Zinn, K.R, Chaudhuri, T.R, Szafran, A.A, O'Quinn, D, Weaver, C, Dugger, K, Lamar, D, Kesterson, R.A, Wang, X, Frank, S.J

“…There has been a rapid growth of bioluminescence imaging applications in small animal models in recent years, propelled by the availability of instruments,…”
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Production of no-carrier-added 64Cu from zinc metal irradiated under boron shielding by Zinn, K R, Chaudhuri, T R, Cheng, T P, Morris, J S, Meyer, Jr, W A

“…Positron emission tomography offers advantages for radioimmunodiagnosis of cancer but requires radionuclides of appropriate half-life that have high specific…”
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Detection of ovarian cancer by 198Au-labeled human monoclonal antibody by Chaudhuri, T R, Zinn, K R, Morris, J S, McDonald, G A, Llorens, A S, Chaudhuri, T K

“…There is no reliable method for the early diagnosis of ovarian cancer. Radiolabeled monoclonal antibodies have potential to assist in early diagnosis, but they…”
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Bacterial adherence to epithelial cells in bacillary colonization of the respiratory tract by Johanson, Jr, W G, Higuchi, J H, Chaudhuri, T R, Woods, D E

“…Bacterial colonization of mucosal surfaces may be mediated by bacterial adherence to epithelial cells. To study the role of adherence in gram-negative…”
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Detection of disseminated breast cancer growth and treatment response using non-invasive bioluminescence imaging by Chaudhuri, T. R., Cao, Z., Ponnazhagan, S., Stargel, A., Simhadri, P. L., Zhou, T., Lobuglio, A. F., Buchsbaum, D. J., Zinn, K. R.

“…Abstract only…”
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Detection of disseminated breast cancer growth and treatment response using non-invasive bioluminescence imaging by Chaudhuri, T. R., Cao, Z., Ponnazhagan, S., Stargel, A., Simhadri, P. L., Zhou, T., Lobuglio, A. F., Buchsbaum, D. J., Zinn, K. R.

“…Abstract only…”
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