Search Results - "Chaudhry, W. W."
-
1
A new strategy for cardiac protection
Published in eLife (02-11-2023)“…It may be possible to treat cardiac hypertrophy and injury by using drugs that inhibit a protein called SIRT2…”
Get full text
Journal Article -
2
Regulation of Cardiomyocyte Division During Cardiac Regeneration
Published in Current cardiology reports (01-07-2023)“…Purpose of Review This review explores efforts made over the previous three decades to determine mechanisms of cardiomyocyte cell division. Many investigators…”
Get full text
Journal Article -
3
Cyclin A2 induces cardiac regeneration after myocardial infarction through cytokinesis of adult cardiomyocytes
Published in Science translational medicine (19-02-2014)“…Cyclin A2 (Ccna2), normally silenced after birth in the mammalian heart, can induce cardiac repair in small-animal models of myocardial infarction. We report…”
Get more information
Journal Article -
4
Cyclin A2 Mediates Cardiomyocyte Mitosis in the Postmitotic Myocardium
Published in The Journal of biological chemistry (20-08-2004)“…Cell cycle withdrawal limits proliferation of adult mammalian cardiomyocytes. Therefore, the concept of stimulating myocyte mitotic divisions has dramatic…”
Get full text
Journal Article -
5
Therapeutic delivery of cyclin A2 induces myocardial regeneration and enhances cardiac function in ischemic heart failure
Published in Circulation (New York, N.Y.) (04-07-2006)“…Heart failure is a global health concern. As a novel therapeutic strategy, the induction of endogenous myocardial regeneration was investigated by initiating…”
Get full text
Conference Proceeding Journal Article -
6
Cyclin A2 Induces Cardiac Regeneration After Myocardial Infarction and Prevents Heart Failure
Published in Circulation research (22-06-2007)“…Mammalian myocardial infarction is typically followed by scar formation with eventual ventricular dilation and heart failure. Here we present a novel model…”
Get full text
Journal Article -
7
Direct comparisons of commercial weight-loss programs on weight, waist circumference, and blood pressure: a systematic review
Published in BMC public health (01-06-2016)“…Obesity is common in the U.S. and many individuals turn to commercial programs to lose weight. Our objective was to directly compare weight loss, waist…”
Get full text
Journal Article -
8
Pop-Out Myocardial Infarction Induction in Mice
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Myocardial infarction (MI) in mice is a widely used surgical model in preclinical cardiac repair studies to recapitulate human cardiovascular ischemic disease…”
Get more information
Journal Article -
9
Health Care Workers and War in the Middle East
Published in JAMA : the journal of the American Medical Association (02-01-2024)Get full text
Journal Article -
10
Efficacy of commercial weight-loss programs: an updated systematic review
Published in Annals of internal medicine (07-04-2015)“…Commercial and proprietary weight-loss programs are popular obesity treatment options, but their efficacy is unclear. To compare weight loss, adherence, and…”
Get full text
Journal Article -
11
Cardiac Regeneration: Time to Revisit Nature
Published in Circulation research (22-06-2018)Get full text
Journal Article -
12
Stability of Body Weight in Type 2 Diabetes
Published in Diabetes care (01-03-2006)“…OBJECTIVE:--There is a concern that an "epidemic of obesity" is occurring in Western societies. One consequence of obesity is that type 2 diabetes may develop…”
Get full text
Journal Article -
13
Chimerism as the basis for organ repair
Published in Annals of the New York Academy of Sciences (01-03-2021)“…Organ and tissue repair are complex processes involving signaling molecules, growth factors, and cell cycle regulators that act in concert to promote cell…”
Get full text
Journal Article -
14
Pulsed Field Ablation of the Porcine Ventricle Using a Focal Lattice-Tip Catheter
Published in Circulation. Arrhythmia and electrophysiology (01-09-2022)“…Our understanding of catheter-based pulsed field ablation (PFA) of the ventricular myocardium is limited. We conducted a series of exploratory evaluations of…”
Get full text
Journal Article -
15
Stepping Out of the Palace of Luxury: Mindfulness and Modern Psychiatry
Published in Biological psychiatry (1969) (15-07-2022)Get full text
Journal Article -
16
Ultrastructural insights from myocardial ablation lesions from microsecond pulsed field vs radiofrequency energy
Published in Heart rhythm (01-04-2024)“…Ultrastructural findings immediately after pulsed field ablation (PFA) of the myocardium have not been described. The purpose of this study was to elucidate…”
Get full text
Journal Article -
17
Chromatin immunoprecipitation of adult murine cardiomyocytes
Published in Current protocols in cell biology (01-03-2013)“…This unit describes a streamlined two-step protocol for the isolation of adult murine cardiomyocytes with subsequent Chromatin ImmunoPrecipitation (ChIP)…”
Get more information
Journal Article -
18
Multipotent fetal-derived Cdx2 cells from placenta regenerate the heart
Published in Proceedings of the National Academy of Sciences - PNAS (11-06-2019)“…The extremely limited regenerative potential of adult mammalian hearts has prompted the need for novel cell-based therapies that can restore contractile…”
Get full text
Journal Article -
19
Electrophysiology, Pathology, and Imaging of Pulsed Field Ablation of Scarred and Healthy Ventricles in Swine
Published in Circulation. Arrhythmia and electrophysiology (01-01-2023)“…Pulsed field ablation (PFA) has recently been shown to penetrate ischemic scar, but details on its efficacy, risk of arrhythmias, and imaging insights are…”
Get full text
Journal Article -
20
Fetal Cells Traffic to Injured Maternal Myocardium and Undergo Cardiac Differentiation
Published in Circulation research (06-01-2012)“…RATIONALE:Fetal cells enter the maternal circulation during pregnancy and may persist in maternal tissue for decades as microchimeras. OBJECTIVE:Based on…”
Get full text
Journal Article