Search Results - "Chaudhary, Adeel G A"
-
1
Anticancer compound plumbagin and its molecular targets: a structural insight into the inhibitory mechanisms using computational approaches
Published in PloS one (27-02-2014)“…Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) is a naphthoquinone derivative from the roots of plant Plumbago zeylanica and belongs to one of the largest…”
Get full text
Journal Article -
2
Cyclin D1 as a therapeutic target of renal cell carcinoma- a combined transcriptomics, tissue microarray and molecular docking study from the Kingdom of Saudi Arabia
Published in BMC cancer (30-09-2016)“…Renal cell carcinoma (RCC) is a seventh ranked malignancy with poor prognosis. RCC is lethal at metastatic stage as it does not respond to conventional…”
Get full text
Journal Article -
3
Transcriptomics profiling study of breast cancer from Kingdom of Saudi Arabia revealed altered expression of Adiponectin and Fatty Acid Binding Protein4: Is lipid metabolism associated with breast cancer?
Published in BMC genomics (15-01-2015)“…Breast cancer incidence rates are increasing at an alarming rate among Saudi Arabian females. Most molecular genetic discoveries on breast cancer and other…”
Get full text
Journal Article -
4
Alzheimer's disease and type 2 diabetes: exploring the association to obesity and tyrosine hydroxylase
Published in CNS & neurological disorders drug targets (01-06-2012)“…Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are two debilitating health disorders afflicting millions worldwide. Recent research has revealed…”
Get more information
Journal Article -
5
Molecular interaction of the antineoplastic drug, methotrexate with human brain acetylcholinesterase: a docking study
Published in CNS & neurological disorders drug targets (01-03-2012)“…This study describes molecular interactions between human brain acetylcholinesterase (AChE) and the well known anti-neoplastic drug, methotrexate (MTX) and its…”
Get more information
Journal Article -
6
An Interleukin-1 Genotype Is Associated with Fatal Outcome of Meningococcal Disease
Published in The Journal of infectious diseases (01-11-2000)“…To determine whether known variants of the interleukin-1 (IL-1) and tumor necrosis factor (TNF) gene families are associated with severe manifestations of…”
Get full text
Journal Article -
7
Cancer Chemoprevention by Polyphenols and Their Potential Application as Nanomedicine
Published in Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews (2013)“…Today cancer is a leading cause of death among the developed countries. Its highly complex nature makes it difficult to understand as it entails multiple…”
Get full text
Journal Article -
8
Biomarkers for virus-induced hepatocellular carcinoma (HCC)
Published in Infection, genetics and evolution (01-08-2014)“…Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and is advanced by severe viral hepatitis B or C (HBV or HCV) as well as alcoholic…”
Get full text
Journal Article -
9
Potential mechanisms of hepatitis B virus induced liver injury
Published in World journal of gastroenterology : WJG (21-09-2014)“…Chronic active hepatitis(CAH) is acknowledged as an imperative risk factor for the development of liver injury and hepatocellular carcinoma.The histological…”
Get full text
Journal Article -
10
Expression of matrix metalloproteinases (MMPs) in primary human breast cancer: MMP-9 as a potential biomarker for cancer invasion and metastasis
Published in Anticancer research (01-03-2014)“…Breast cancer (BC) is the most common type of cancer in Saudi women. Matrix metalloproteinases (MMPs) are endopeptidases with the ability to degrade…”
Get full text
Journal Article -
11
Novel Genetic Mechanism of Venetoclax Resistance in AML: BAX Deletion
Published in Blood (13-11-2019)“…Venetoclax is a highly selective B-cell lymphoma 2 (BCL-2) inhibitor which recently received accelerated US FDA approval for use in combination with…”
Get full text
Journal Article -
12
New Anticancer Agents: Recent Developments in Tumor Therapy
Published in Anticancer research (01-07-2012)“…Increasing recurrence of mammalian tumors and severe side-effects of chemotherapeutic agents reduce the clinical efficacy of a large variety of anticancer…”
Get full text
Journal Article -
13
The Influence of Interleukin Gene Polymorphism on Expression of Interleukin–1β and Tumor Necrosis Factor–α in Periodontal Tissue and Gingival Crevicular Fluid
Published in Journal of periodontology (1970) (01-06-1999)“…Background: A specific composite genotype of the polymorphic interleukin‐1 (IL‐1) gene cluster has recently been associated with severe periodontitis. One…”
Get full text
Journal Article -
14
BioSearch: an in-house developed lab information management system for center of excellence in genomic medicine research
Published in BMC genomics (02-04-2014)“…Doc number: P41…”
Get full text
Journal Article -
15
Gene expression profiling of lymph node positive-negative metastasis of primary breast cancer in Saudi Arabian patients
Published in BMC genomics (02-04-2014)“…Doc number: P55…”
Get full text
Journal Article -
16
High-density expression profiling of renal cell carcinomas from Saudi Arabia: a preliminary study
Published in BMC genomics (02-04-2014)“…Doc number: P36…”
Get full text
Journal Article -
17
Anticancer Compound Plumbagin and Its Molecular Targets: A Structural Insight into the Inhibitory Mechanisms Using Computational Approaches: e87309
Published in PloS one (01-02-2014)“…Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) is a naphthoquinone derivative from the roots of plant Plumbago zeylanica and belongs to one of the largest…”
Get full text
Journal Article