Search Results - "Chaudhari, Sujata S"

Urease is an essential component of the acid response network of Staphylococcus aureus and is required for a persistent murine kidney infection by Zhou, Chunyi, Bhinderwala, Fatema, Lehman, McKenzie K, Thomas, Vinai C, Chaudhari, Sujata S, Yamada, Kelsey J, Foster, Kirk W, Powers, Robert, Kielian, Tammy, Fey, Paul D

“…Staphylococcus aureus causes acute and chronic infections resulting in significant morbidity. Urease, an enzyme that generates NH3 and CO2 from urea, is key to…”
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Staphylococcus aureus ATP Synthase Promotes Biofilm Persistence by Influencing Innate Immunity by Bosch, Megan E, Bertrand, Blake P, Heim, Cortney E, Alqarzaee, Abdulelah A, Chaudhari, Sujata S, Aldrich, Amy L, Fey, Paul D, Thomas, Vinai C, Kielian, Tammy

“…is a major cause of prosthetic joint infection (PJI), which is characterized by biofilm formation. biofilm skews the host immune response toward an…”
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Knickkopf protein protects and organizes chitin in the newly synthesized insect exoskeleton by Chaudhari, Sujata S, Arakane, Yasuyuki, Specht, Charles A, Moussian, Bernard, Boyle, Daniel L, Park, Yoonseong, Kramer, Karl J, Beeman, Richard W, Muthukrishnan, Subbaratnam

“…During each molting cycle of insect development, synthesis of new cuticle occurs concurrently with the partial degradation of the overlying old exoskeleton…”
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A central role for carbon-overflow pathways in the modulation of bacterial cell death by Thomas, Vinai Chittezham, Sadykov, Marat R, Chaudhari, Sujata S, Jones, Joselyn, Endres, Jennifer L, Widhelm, Todd J, Ahn, Jong-Sam, Jawa, Randeep S, Zimmerman, Matthew C, Bayles, Kenneth W

“…Similar to developmental programs in eukaryotes, the death of a subpopulation of cells is thought to benefit bacterial biofilm development. However mechanisms…”
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The Staphylococcus aureus CidA and LrgA Proteins Are Functional Holins Involved in the Transport of By-Products of Carbohydrate Metabolism by Endres, Jennifer L, Chaudhari, Sujata S, Zhang, Xinyan, Prahlad, Janani, Wang, Shu-Qi, Foley, Lily A, Luca, Sorin, Bose, Jeffrey L, Thomas, Vinai C, Bayles, Kenneth W

“…The Staphylococcus aureus and operons encode members of a well-conserved family of proteins thought to be involved in programmed cell death (PCD). Based on the…”
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A critical role for staphylococcal nitric oxide synthase in controlling flavohemoglobin toxicity by Singh, Ryan M., Chaudhari, Sujata S., Panda, Sasmita, Hutfless, Elizabeth H., Heim, Cortney E., Shinde, Dhananjay, Alqarzaee, Abdulelah A., Sladek, Margaret, Kumar, Vineet, Zimmerman, Matthew C., Fey, Paul D., Kielian, Tammy, Thomas, Vinai C.

“…Most coagulase-negative staphylococcal species, including the opportunistic pathogen Staphylococcus epidermidis, struggle to maintain redox homeostasis and…”
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Nitrite Derived from Endogenous Bacterial Nitric Oxide Synthase Activity Promotes Aerobic Respiration by Chaudhari, Sujata S, Kim, Minji, Lei, Shulei, Razvi, Fareha, Alqarzaee, Abdulelah A, Hutfless, Elizabeth H, Powers, Robert, Zimmerman, Matthew C, Fey, Paul D, Thomas, Vinai C

“…Macrophage-derived nitric oxide (NO·) is a crucial effector against invading pathogens. Yet, paradoxically, several bacterial species, including some…”
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Functional specialization among members of Knickkopf family of proteins in insect cuticle organization by Chaudhari, Sujata S, Moussian, Bernard, Specht, Charles A, Arakane, Yasuyuki, Kramer, Karl J, Beeman, Richard W, Muthukrishnan, Subbaratnam

“…Our recent study on the functional analysis of the Knickkopf protein from T. castaneum (TcKnk), indicated a novel role for this protein in protection of chitin…”
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Retroactive maintains cuticle integrity by promoting the trafficking of Knickkopf into the procuticle of Tribolium castaneum by Chaudhari, Sujata S, Arakane, Yasuyuki, Specht, Charles A, Moussian, Bernard, Kramer, Karl J, Muthukrishnan, Subbaratnam, Beeman, Richard W

“…Molting, or the replacement of the old exoskeleton with a new cuticle, is a complex developmental process that all insects must undergo to allow unhindered…”
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Knickkopf and retroactive proteins are required for formation of laminar serosal procuticle during embryonic development of Tribolium castaneum by Chaudhari, Sujata S., Noh, Mi Young, Moussian, Bernard, Specht, Charles A., Kramer, Karl J., Beeman, Richard W., Arakane, Yasuyuki, Muthukrishnan, Subbaratnam

“…Chitin, a homopolymer of β-1-4-linked N-acetylglucosamine synthesized by chitin synthase A (Chs-A), is organized in the procuticle of the postembryonic cuticle…”
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A dysfunctional tricarboxylic acid cycle enhances fitness of Staphylococcus epidermidis during β-lactam stress by Thomas, Vinai C, Chittezham Thomas, Vinai, Kinkead, Lauren C, Janssen, Ashley, Schaeffer, Carolyn R, Woods, Keith M, Lindgren, Jill K, Peaster, Jonathan M, Chaudhari, Sujata S, Sadykov, Marat, Jones, Joselyn, AbdelGhani, Sameh M Mohamadi, Zimmerman, Matthew C, Bayles, Kenneth W, Somerville, Greg A, Fey, Paul D

“…A recent controversial hypothesis suggested that the bactericidal action of antibiotics is due to the generation of endogenous reactive oxygen species (ROS), a…”
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Potassium Uptake Modulates Staphylococcus aureus Metabolism by Gries, Casey M, Sadykov, Marat R, Bulock, Logan L, Chaudhari, Sujata S, Thomas, Vinai C, Bose, Jeffrey L, Bayles, Kenneth W

“…As a leading cause of community-associated and nosocomial infections, Staphylococcus aureus requires sophisticated mechanisms that function to maintain…”
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Role of Staphylococcus aureus Formate Metabolism during Prosthetic Joint Infection by Bertrand, Blake P, Heim, Cortney E, West, Sean C, Chaudhari, Sujata S, Ali, Hesham, Thomas, Vinai C, Kielian, Tammy

“…Biofilms are bacterial communities characterized by antibiotic tolerance. Staphylococcus aureus is a leading cause of biofilm infections on medical devices,…”
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An optimized artificial blood feeding assay to study tick cuticle biology by Kozisek, Faith, Cenovic, Jonathon, Armendariz, Savannah, Muthukrishnan, Subbaratnam, Park, Yoonseong, Thomas, Vinai C., Chaudhari, Sujata S.

“…Ticks, ectoparasitic arachnids, are prominent disease vectors impacting both humans and animals. Their unique blood-feeding phase involves significant…”
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Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection by Heim, Cortney E., Bosch, Megan E., Yamada, Kelsey J., Aldrich, Amy L., Chaudhari, Sujata S., Klinkebiel, David, Gries, Casey M., Alqarzaee, Abdulelah A., Li, Yixuan, Thomas, Vinai C., Seto, Edward, Karpf, Adam R., Kielian, Tammy

“…Staphylococcus aureus is a leading cause of biofilm-associated prosthetic joint infection (PJI), resulting in considerable disability and prolonged treatment…”
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Staphylococcal ClpXP protease targets the cellular antioxidant system to eliminate fitness-compromised cells in stationary phase by Alqarzaee, Abdulelah A., Chaudhari, Sujata S., Islam, Mohammad Mazharul, Kumar, Vikas, Zimmerman, Matthew C., Saha, Rajib, Bayles, Kenneth W., Frees, Dorte, Thomas, Vinai C.

“…The transition from growth to stationary phase is a natural response of bacteria to starvation and stress. When stress is alleviated and more favorable growth…”
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SrrAB Modulates Staphylococcus aureus Cell Death through Regulation of cidABC Transcription by Windham, Ian H, Chaudhari, Sujata S, Bose, Jeffrey L, Thomas, Vinai C, Bayles, Kenneth W

“…The death and lysis of a subpopulation in Staphylococcus aureus biofilm cells are thought to benefit the surviving population by releasing extracellular DNA, a…”
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The LysR‐type transcriptional regulator, CidR, regulates stationary phase cell death in Staphylococcus aureus by Chaudhari, Sujata S., Thomas, Vinai C., Sadykov, Marat R., Bose, Jeffrey L., Ahn, Daniel J., Zimmerman, Matthew C., Bayles, Kenneth W.

“…Summary The Staphylococcus aureus LysR‐type transcriptional regulator, CidR, activates the expression of two operons including cidABC and alsSD that display…”
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Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species Tribolium castaneum by Merzendorfer, Hans, Kim, Hee Shin, Chaudhari, Sujata S., Kumari, Meera, Specht, Charles A., Butcher, Stephen, Brown, Susan J., Robert Manak, J., Beeman, Richard W., Kramer, Karl J., Muthukrishnan, Subbaratnam

“…Several benzoylphenyl urea-derived insecticides such as diflubenzuron (DFB, Dimilin®) are in wide use to control various insect pests. Although this class of…”
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A Dysfunctional Tricarboxylic Acid Cycle Enhances Fitness of Staphylococcus epidermidis during β-Lactam Stress by Thomas, Vinai C., Kinkead, Lauren C., Janssen, Ashley, Schaeffer, Carolyn R., Woods, Keith M., Lindgren, Jill K., Peaster, Jonathan M., Chaudhari, Sujata S., Sadykov, Marat, Jones, Joselyn, Mohamadi AbdelGhani, Sameh M., Zimmerman, Matthew C., Bayles, Kenneth W., Somerville, Greg A., Fey, Paul D.

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