Search Results - "Chatziathanasiadou, Maria V."

Functional Components of Carob Fruit: Linking the Chemical and Biological Space by Goulas, Vlasios, Stylos, Evgenios, Chatziathanasiadou, Maria V, Mavromoustakos, Thomas, Tzakos, Andreas G

“…The contribution of natural products to the drug-discovery pipeline has been remarkable since they have served as a rich source for drug development and…”
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NMR-Based Chemical Profiling, Isolation and Evaluation of the Cytotoxic Potential of the Diterpenoid Siderol from Cultivated Sideritis euboea Heldr by Tomou, Ekaterina-Michaela, Chatziathanasiadou, Maria V, Chatzopoulou, Paschalina, Tzakos, Andreas G, Skaltsa, Helen

“…Diterpenes are characteristic compounds from the genus L., possessing an array of biological activities. Siderol is the main constituent of the -kaurene…”
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Lipophilic ester and amide derivatives of rosmarinic acid protect cells against H2O2-induced DNA damage and apoptosis: The potential role of intracellular accumulation and labile iron chelation by Gerogianni, Paraskevi S., Chatziathanasiadou, Maria V., Diamantis, Dimitrios A., Tzakos, Andreas G., Galaris, Dimitrios

“…Phenolic acids represent abundant components contained in human diet. However, the negative charge in their carboxylic group limits their capacity to diffuse…”
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Synthetic Analogues of Aminoadamantane as Influenza Viral Inhibitors-In Vitro, In Silico and QSAR Studies by Chayrov, Radoslav, Parisis, Nikolaos A, Chatziathanasiadou, Maria V, Vrontaki, Eleni, Moschovou, Kalliopi, Melagraki, Georgia, Sbirkova-Dimitrova, Hristina, Shivachev, Boris, Schmidtke, Michaela, Mitrev, Yavor, Sticha, Martin, Mavromoustakos, Thomas, Tzakos, Andreas G, Stankova, Ivanka

“…A series of nineteen amino acid analogues of amantadine (Amt) and rimantadine (Rim) were synthesized and their antiviral activity was evaluated against…”
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Unveiling the interaction profile of rosmarinic acid and its bioactive substructures with serum albumin by Papaemmanouil, Christina, Chatziathanasiadou, Maria V., Chatzigiannis, Christos, Chontzopoulou, Eleni, Mavromoustakos, Thomas, Grdadolnik, Simona Golic, Tzakos, Andreas G.

“…Rosmarinic acid, a phytochemical compound, bears diverse pharmaceutical profile. It is composed by two building blocks: caffeic acid and a salvianic acid unit…”
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Unveiling the Thermodynamic Aspects of Drug-Cyclodextrin Interactions Through Isothermal Titration Calorimetry by Chatziathanasiadou, Maria V, Mavromoustakos, Thomas, Tzakos, Andreas G

“…Due to their low toxicity and high aqueous solubility, cyclodextrins have emerged as a distinctive class of supramolecules with wide application in the…”
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Preparation and Biophysical Characterization of Quercetin Inclusion Complexes with β‑Cyclodextrin Derivatives to be Formulated as Possible Nose-to-Brain Quercetin Delivery Systems by Manta, Konstantina, Papakyriakopoulou, Paraskevi, Chountoulesi, Maria, Diamantis, Dimitrios A, Spaneas, Dimitrios, Vakali, Vasiliki, Naziris, Nikolaos, Chatziathanasiadou, Maria V, Andreadelis, Ioannis, Moschovou, Kalliopi, Athanasiadou, Ioanna, Dallas, Paraskevas, Rekkas, Dimitrios M, Demetzos, Costas, Colombo, Gaia, Banella, Sabrina, Javornik, Uroš, Plavec, Janez, Mavromoustakos, Thomas, Tzakos, Andreas G, Valsami, Georgia

“…Quercetin (Que) is a flavonoid associated with high oxygen radical scavenging activity and potential neuroprotective activity against Alzheimer’s disease…”
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Liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS) based bioavailability determination of the major classes of phytochemicals by Stylos, Evgenios, Chatziathanasiadou, Maria V., Syriopoulou, Aggeliki, Tzakos, Andreas G.

“…•LC–MS/MS sensitivity and specificity should be exploited in phytochemical research.•Knowledge on LC–MS/MS quantification of phytochemicals in plasma is…”
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Mapping the interactions and bioactivity of quercetin⿿(2-hydroxypropyl)-β-cyclodextrin complex by Kellici, Tahsin F., Chatziathanasiadou, Maria V., Diamantis, Dimitris, Chatzikonstantinou, Alexandra V., Andreadelis, Ioannis, Christodoulou, Eirini, Valsami, Georgia, Mavromoustakos, Thomas, Tzakos, Andreas G.

“…[Display omitted] Natural products have served as a rich source for drug discovery and development. In the last decade their fruitful integration in the drug…”
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A Novel Fluorescent Gemcitabine Prodrug That Follows a Nucleoside Transporter‐Independent Internalization and Bears Enhanced Therapeutic Efficacy With Respect to Gemcitabine by Vrettos, Eirinaios Ι., Kyrkou, Stavroula G., Zoi, Vasiliki, Giannakopoulou, Maria, Chatziathanasiadou, Maria V., Kanaki, Zoi, Agalou, Adamantia, Bistas, Vasileios‐Panagiotis, Kougioumtzi, Anastasia, Karampelas, Theodoros, Diamantis, Dimitrios A., Murphy, Carol, Beis, Dimitris, Klinakis, Apostolos, Tamvakopoulos, Constantin, Kyritsis, Athanasios P., Alexiou, George A., Tzakos, Andreas G.

“…The multiplexity of cancer has rendered it the second leading cause of mortality worldwide and theragnostic prodrugs have gained popularity in recent years as…”
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Biotin-Yellow a biotin guided NIR turn-on fluorescent probe for cancer targeted diagnosis by Diamantis, Dimitrios A., Agalou, Adamantia, Chatziathanasiadou, Maria V., Markopoulos, Georgios S., Bellou, Sofia, Kanaki, Zoi, Crook, Timothy, Syed, Nelofer, Rampias, Theodoros, Klinakis, Apostolos, Kolettas, Evangelos, Beis, Dimitris, Tzakos, Andreas G.

“…[Display omitted] •The tumor-targeting and biothiol activatable fluorescent probe Biotin-Yellow was developed.•Biotin-Yellow is non-toxic, it can effectively…”
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Bioinspired tailoring of fluorogenic thiol responsive antioxidant precursors to protect cells against H2O2-induced DNA damage by Diamantis, Dimitrios A., Oblukova, Michaela, Chatziathanasiadou, Maria V., Gemenetzi, Aikaterini, Papaemmanouil, Christina, Gerogianni, Paraskevi S., Syed, Nelofer, Crook, Timothy, Galaris, Dimitrios, Deligiannakis, Yiannis, Sokolova, Romana, Tzakos, Andreas G.

“…Natural antioxidants, like phenolic acids, possess a unique chemical space that can protect cellular components from oxidative stress. However, their polar…”
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Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma by Perryman, Richard, Renziehausen, Alexander, Shaye, Hamidreza, Kostagianni, Androniki D, Tsiailanis, Antonis D, Thorne, Thomas, Chatziathanasiadou, Maria V, Sivolapenko, Gregory B, El Mubarak, Mohamed Ahmed, Han, Gye Won, Zarzycka, Barbara, Katritch, Vsevolod, Lebon, Guillaume, Nigro, Cristiana Lo, Lattanzio, Laura, Morse, Sophie V, Choi, James J, O'Neill, Kevin, Kanaki, Zoi, Klinakis, Apostolos, Crook, Tim, Cherezov, Vadim, Tzakos, Andreas G, Syed, Nelofer

“…Glioblastoma (GBM) is an aggressive malignant primary brain tumor with limited therapeutic options. We show that the angiotensin II (AngII) type 2 receptor…”
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Inhibition of the angiotensin II type 2 receptor AT 2 R is a novel therapeutic strategy for glioblastoma by Perryman, Richard, Renziehausen, Alexander, Shaye, Hamidreza, Kostagianni, Androniki D, Tsiailanis, Antonis D, Thorne, Thomas, Chatziathanasiadou, Maria V, Sivolapenko, Gregory B, El Mubarak, Mohamed Ahmed, Han, Gye Won, Zarzycka, Barbara, Katritch, Vsevolod, Lebon, Guillaume, Lo Nigro, Cristiana, Lattanzio, Laura, Morse, Sophie V, Choi, James J, O'Neill, Kevin, Kanaki, Zoi, Klinakis, Apostolos, Crook, Tim, Cherezov, Vadim, Tzakos, Andreas G, Syed, Nelofer

“…Glioblastoma (GBM) is an aggressive malignant primary brain tumor with limited therapeutic options. We show that the angiotensin II (AngII) type 2 receptor (AT…”
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Tailoring naringenin conjugates with amplified and triple antiplatelet activity profile: Rational design, synthesis, human plasma stability and in vitro evaluation by Stylos, Evgenios, Chatziathanasiadou, Maria V., Tsiailanis, Antonis, Kellici, Tahsin F., Tsoumani, Maria, Kostagianni, Androniki D., Deligianni, Maria, Tselepis, Alexandros D., Tzakos, Andreas G.

“…The current standard-of-care antiplatelet therapy in cardiovascular disease patients is consisted of cyclooxygenase-1 (COX-1) inhibitor aspirin, along with a…”
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Development of novel GnRH and Tat 48-60 based luminescent probes with enhanced cellular uptake and bioimaging profile by Kougioumtzi, Anastasia, Chatziathanasiadou, Maria V, Vrettos, Eirinaios I, Sayyad, Nisar, Sakka, Mariana, Stathopoulos, Panagiotis, Mantzaris, Michalis D, Ganai, Ab Majeed, Karpoormath, Rajshekhar, Vartholomatos, Georgios, Tsikaris, Vassilios, Lazarides, Theodore, Murphy, Carol, Tzakos, Andreas G

“…There is a clear need to develop photostable chromophores for bioimaging with respect to the classically utilized green fluorescent dye fluorescein. Along…”
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Exploring the interactions of irbesartan and irbesartan–2-hydroxypropyl-β-cyclodextrin complex with model membranes by Liossi, Αdamantia S., Ntountaniotis, Dimitrios, Kellici, Tahsin F., Chatziathanasiadou, Maria V., Megariotis, Grigorios, Mania, Maria, Becker-Baldus, Johanna, Kriechbaum, Manfred, Krajnc, Andraž, Christodoulou, Eirini, Glaubitz, Clemens, Rappolt, Michael, Amenitsch, Heinz, Mali, Gregor, Theodorou, Doros N., Valsami, Georgia, Pitsikalis, Marinos, Iatrou, Hermis, Tzakos, Andreas G., Mavromoustakos, Thomas

“…The interactions of irbesartan (IRB) and irbesartan–2-hydroxypropyl-β-cyclodextrin (HP-β-CD) complex with dipalmitoyl phosphatidylcholine (DPPC) bilayers have…”
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Amplifying and broadening the cytotoxic profile of quercetin in cancer cell lines through bioconjugation by Chatziathanasiadou, Maria V., Geromichalou, Elena G., Sayyad, Nisar, Vrettos, Eirinaios I., Katsikoudi, Antigoni, Stylos, Evgenios, Bellou, Sofia, Geromichalos, George D., Tzakos, Andreas G.

“…Quercetin is a flavonoid presenting cytotoxicity against different cancer cell lines. We hypothesized that its core could serve as a scaffold for generating…”
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Host–Guest Interactions between Candesartan and Its Prodrug Candesartan Cilexetil in Complex with 2‑Hydroxypropyl-β-cyclodextrin: On the Biological Potency for Angiotensin II Antagonism by Ntountaniotis, Dimitrios, Andreadelis, Ioannis, Kellici, Tahsin F, Karageorgos, Vlasios, Leonis, Georgios, Christodoulou, Eirini, Kiriakidi, Sofia, Becker-Baldus, Johanna, Stylos, Evgenios K, Chatziathanasiadou, Maria V, Chatzigiannis, Christos M, Damalas, Dimitrios E, Aksoydan, Busecan, Javornik, Uroš, Valsami, Georgia, Glaubitz, Clemens, Durdagi, Serdar, Thomaidis, Nikolaos S, Kolocouris, Antonios, Plavec, Janez, Tzakos, Andreas G, Liapakis, George, Mavromoustakos, Thomas

“…Renin–angiotensin aldosterone system inhibitors are for a long time extensively used for the treatment of cardiovascular and renal diseases. AT1 receptor…”
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Exploration of Betalains and Determination of the Antioxidant and Cytotoxicity Profile of Orange and Purple Opuntia spp. Cultivars in Greece by Tsiailanis, Antonios D., Chatzigiannis, Christos M., Papaemmanouil, Christina D., Chatziathanasiadou, Maria V., Chaloulos, Panagiotis, Riba, Isabel, Mullard, Graham, Wiczkowski, Wiesław, Koutinas, Apostolos, Mandala, Ioanna, Tzakos, Andreas G.

“…Replacing synthetic dyes with natural pigments has gained great attention over the past years in the food industry, due to the increased alertness of consumers…”
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