Search Results - "Chaturvedi, Ashok K."
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Dispersion as an important step in the Candida albicans biofilm developmental cycle
Published in PLoS pathogens (01-03-2010)“…Biofilms are dynamic microbial communities in which transitions between planktonic and sessile modes of growth occur interchangeably in response to different…”
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Screening the medicine for malaria venture's Pandemic Response Box to identify novel inhibitors of Candida albicans and Candida auris biofilm formation
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01-11-2023)“…Candida spp. are opportunistic yeasts capable of forming biofilms, which contribute to resistance, increasing the urgency for new effective antifungal…”
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3
Vaccine-mediated immune responses to experimental pulmonary Cryptococcus gattii infection in mice
Published in PloS one (13-08-2014)“…Cryptococcus gattii is a fungal pathogen that can cause life-threatening respiratory and disseminated infections in immune-competent and immune-suppressed…”
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4
Characteristics of Candida albicans Biofilms Grown in a Synthetic Urine Medium
Published in Journal of Clinical Microbiology (01-12-2009)“…Urinary tract infections (UTIs) are the most common type of nosocomial infection, and Candida albicans is the most frequent organism causing fungal UTIs…”
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5
Design of a Simple Model of Candida albicans Biofilms Formed under Conditions of Flow: Development, Architecture, and Drug Resistance
Published in Mycopathologia (1975) (01-09-2009)“…Candida albicans biofilms on most medical devices are exposed to a flow of body fluids that provide water and nutrients to the fungal cells. While C. albicans…”
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High-Throughput Screening of the Repurposing Hub Library to Identify Drugs with Novel Inhibitory Activity against Candida albicans and Candida auris Biofilms
Published in Journal of fungi (Basel) (27-08-2023)“…Candidiasis is one of the most frequent nosocomial infections affecting an increasing number of at-risk patients. Candida albicans remains the most frequent…”
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Induction of Broad-Spectrum Protective Immunity against Disparate Cryptococcus Serotypes
Published in Frontiers in immunology (30-10-2017)“…Cryptococcosis is a fungal disease caused by multiple serotypes; particularly (serotypes A and D) and (serotypes B and C). To date, there is no clinically…”
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Efficacy of a Genetically Engineered Candida albicans tet-NRG1 Strain as an Experimental Live Attenuated Vaccine against Hematogenously Disseminated Candidiasis
Published in Clinical and Vaccine Immunology (01-03-2009)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Use of a Genetically Engineered Strain To Evaluate the Pathogenic Potential of Yeast Cell and Filamentous Forms during Candida albicans Systemic Infection in Immunodeficient Mice
Published in Infection and Immunity (01-01-2008)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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10
Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents
Published in Bioorganic & medicinal chemistry letters (15-07-2005)“…The synthesis, and antibacterial and antiviral activities of 5– 24 are described. A series of 1,4-naphthoquinone derivatives were synthesized and evaluated for…”
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11
Physiologic Expression of the Candida albicans Pescadillo Homolog Is Required for Virulence in a Murine Model of Hematogenously Disseminated Candidiasis
Published in Eukaryotic Cell (01-12-2012)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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12
Screening a Repurposing Library for Inhibitors of Multidrug-Resistant Candida auris Identifies Ebselen as a Repositionable Candidate for Antifungal Drug Development
Published in Antimicrobial agents and chemotherapy (01-10-2018)“…Since its original isolation in 2009, has spread across the globe as a causative agent of invasive candidiasis. is typically intrinsically resistant to…”
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13
Validation of the tetracycline regulatable gene expression system for the study of the pathogenesis of infectious disease
Published in PloS one (25-05-2011)“…Understanding the pathogenesis of infectious disease requires the examination and successful integration of parameters related to both microbial virulence and…”
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14
Monoclonal immunoglobulin G1 directed against Aspergillus fumigatus cell wall glycoprotein protects against experimental murine aspergillosis
Published in Clinical and Diagnostic Laboratory Immunology (01-09-2005)“…Most of the biological functions related to pathogenicity and virulence reside in the fungal cell wall, which, being the outermost part of the cell, mediates…”
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In Vitro Activity of Miltefosine against Candida albicans under Planktonic and Biofilm Growth Conditions and In Vivo Efficacy in a Murine Model of Oral Candidiasis
Published in Antimicrobial agents and chemotherapy (01-12-2015)“…The generation of a new antifungal against Candida albicans biofilms has become a major priority, since biofilm formation by this opportunistic pathogenic…”
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Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation
Published in mBio (05-12-2017)“…remains the main etiologic agent of candidiasis, the most common fungal infection and now the third most frequent infection in U.S. hospitals. The scarcity of…”
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Repurposing auranofin as an antifungal: In vitro activity against a variety of medically important fungi
Published in Virulence (17-02-2017)“…Repositioning old drugs can significantly decrease the time and effort that it takes to develop novel antifungal therapeutics, which represents a pressing and…”
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18
Methodology for Anti-Cryptococcal Vaccine Development
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…Cryptococcus neoformans and Cryptococcus gattii, the predominant etiological agents of cryptococcosis, are fungal pathogens that cause disease ranging from a…”
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A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance
Published in NPJ biofilms and microbiomes (12-08-2015)“…Background/Objectives: Candida albicans is the principal causative agent of candidiasis, the most common fungal infection in humans. Candidiasis represents the…”
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New antifungal flavonoid glycoside from Vitex negundo
Published in Bioorganic & medicinal chemistry letters (2007)“…New flavone glycoside was isolated along with five known compounds from the leaves of Vitex negundo and evaluated for their antifungal and antibacterial…”
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