Search Results - "Chater, Peter"

Efficacy and safety concerns over the use of mucus modulating agents for drug delivery using nanoscale systems by Chater, Peter I., Wilcox, Matthew D., Pearson, Jeffrey P.

“…Drug delivery to the mucus covered mucosae is fraught with difficulties and many different approaches have been developed to permeate the mucus barrier…”
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Acceptability of alginate enriched bread and its effect on fat digestion in humans by Houghton, David, Wilcox, Matthew D., Brownlee, Iain A., Chater, Peter I., Seal, Chris J., Pearson, Jeffrey P.

“…Lifestyle interventions and physical activity remain the cornerstone of obesity management, as pharmacological therapies (orlistat) are associated with…”
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The effect of seaweed enriched bread on carbohydrate digestion and the release of glucose from food by Wilcox, Matthew D., Cherry, Paul, Chater, Peter I., Yang, Xing, Zulali, Moaz, Okello, Edward J., Seal, Chris J., Pearson, Jeffrey P.

“…•Seaweeds can reduce carbohydrate digestion in a physiologically relevant model.•Baking seaweed into bread can reduce its ability to inhibit carbohydrate…”
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Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown by Crouch, Lucy I., Liberato, Marcelo V., Urbanowicz, Paulina A., Baslé, Arnaud, Lamb, Christopher A., Stewart, Christopher J., Cooke, Katie, Doona, Mary, Needham, Stephanie, Brady, Richard R., Berrington, Janet E., Madunic, Katarina, Wuhrer, Manfred, Chater, Peter, Pearson, Jeffery P., Glowacki, Robert, Martens, Eric C., Zhang, Fuming, Linhardt, Robert J., Spencer, Daniel I. R., Bolam, David N.

“…The thick mucus layer of the gut provides a barrier to infiltration of the underlying epithelia by both the normal microbiota and enteric pathogens. Some…”
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Starch digestion in the upper gastrointestinal tract of humans by Brownlee, Iain A., Gill, Saloni, Wilcox, Matt D., Pearson, Jeff P., Chater, Peter I.

“…Starch provides a large proportion of the dietary energy consumed worldwide. The breakdown of dietary starch is driven by α‐amylase produced by the salivary…”
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Biological activity of alginate and its effect on pancreatic lipase inhibition as a potential treatment for obesity by Houghton, David, Wilcox, Matthew D., Chater, Peter I., Brownlee, Iain A., Seal, Chris J., Pearson, Jeffrey P.

“…Alginates are classed as a dietary fibre and have been shown to inhibit digestive enzymes in vitro, and therefore could be used as an obesity treatment. The…”
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The MUC2 Gene Product: Polymerisation and Post-Secretory Organisation-Current Models by Stanforth, Kyle J, Zakhour, Maria I, Chater, Peter I, Wilcox, Matthew D, Adamson, Beth, Robson, Niamh A, Pearson, Jeffrey P

“…MUC2 mucin, the primary gel-forming component of intestinal mucus, is well researched and a model of polymerisation and post-secretory organisation has been…”
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The properties of the mucus barrier, a unique gel--how can nanoparticles cross it? by Pearson, Jeffrey P, Chater, Peter I, Wilcox, Matthew D

“…The key criterion for a nanoparticle drug-delivery system is the ability to produce substantial bioavailability without damaging the physiological protective…”
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The role of seaweed bioactives in the control of digestion: implications for obesity treatments by Chater, Peter I, Wilcox, Matthew D, Houghton, David, Pearson, Jeffrey P

“…Seaweeds are an underutilised nutritional resource that could not only compliment the current western diet but potentially bring additional health benefits…”
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ζ potential changing nanoparticles as cystic fibrosis transmembrane conductance regulator gene delivery system: an in vitro evaluation by Prüfert, Felix, Bonengel, Sonja, Köllner, Saskia, Griesser, Janine, Wilcox, Matthew D, Chater, Peter I, Pearson, Jeffrey P, Bernkop-Schnürch, Andreas

“…Aim of the study was the development of ζ potential changing nanoparticles as gene delivery system for the cystic fibrosis transmembrane conductance regulator…”
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A Pilot Pre and Post 4 Week Intervention Evaluating the Effect of a Proprietary, Powdered, Plant Based Food on Micronutrient Status, Dietary Intake, and Markers of Health in a Healthy Adult Population by Wilcox, Matthew D, Chater, Peter I, Stanforth, Kyle J, Williams, Rebecca, Brownlee, Iain A, Pearson, Jeffrey P

“…A "balanced, adequate, and varied diet" is recommended as the basis of nutritionally sound diet by the World Health Organisation and national public health…”
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White kidney bean extract as a nutraceutical: effects on gut microbiota, alpha-amylase inhibition, and user experiences by Houghton, David, Shannon, Oliver M, Chater, Peter I, Wilcox, Matthew D, Pearson, Jeffrey P, Stanforth, Kyle, Jordan, Cara, Avery, Leah, Blain, Alasdair P, Joel, Abraham, Jeffers, Ruth, Nolan, Ruth, Nelson, Andrew, Stewart, Christopher J, Malcomson, Fiona C

“…White kidney bean extract (WKBE) is a nutraceutical often advocated as an anti-obesity agent. The main proposed mechanism for these effects is alpha-amylase…”
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Encapsulation of stevia rebaudiana Bertoni aqueous crude extracts by ionic gelation – Effects of alginate blends and gelling solutions on the polyphenolic profile by Arriola, Nathalia D. Aceval, Chater, Peter Ian, Wilcox, Matthew, Lucini, Luigi, Rocchetti, Gabriele, Dalmina, Milene, Pearson, Jeffrey P., de Mello Castanho Amboni, Renata Dias

“…[Display omitted] •Encapsulation of stevia crude extract within two alginate blends by ionic gelation has been assessed.•High encapsulation efficiency of…”
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Dietary fibre and weight loss: Where are we now? by Brownlee, Iain A., Chater, Peter I., Pearson, Jeff P., Wilcox, Matt D.

“…“Dietary fibre” represents a wide spectrum of polysaccharides that escape digestion in the human gastrointestinal tract. The term has been widely associated…”
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Letter: studies of salivary pepsin in patients with gastro‐oesophageal reflux disease by Dettmar, Peter William, Woodcock, Andrew David, Wilcox, Matthew David, Chater, Peter Ian, Pearson, Jeffrey Peter

“…Linked ContentThis article is linked to Race et al and Corfe et al papers. To view these articles, visit https://doi.org/10.1111/apt.15138 and…”
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Inhibitory activity of extracts of Hebridean brown seaweeds on lipase activity by Chater, Peter Ian, Wilcox, Mathew, Cherry, Paul, Herford, Andrew, Mustar, Suraiami, Wheater, Hannah, Brownlee, Iain, Seal, Chris, Pearson, Jeffrey

“…The effect of three Hebridean brown seaweeds on lipase activity was assessed using a turbidimetric lipase activity assay and an in vitro simulation of the…”
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Alginate as a protease inhibitor in vitro and in a model gut system; selective inhibition of pepsin but not trypsin by Chater, Peter Ian, Wilcox, Mathew D., Brownlee, Iain A., Pearson, Jeffrey P.

“…•Alginate inhibits proteolytic activity of pepsin but not trypsin.•Level of pepsin inhibition correlates with alginate F[M].•An in vitro model gut system was…”
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Inhibitory activities of three Malaysian edible seaweeds on lipase and α-amylase by Balasubramaniam, Vimala, Mustar, Suraiami, Mustafa Khalid, Norhayati, Abd Rashed, Aswir, Mohd Noh, Mohd Fairulnizal, Wilcox, Matthew D., Chater, Peter I., Brownlee, Iain A., Pearson, Jeffrey P.

“…Ethanol extracts, dried powders and fibres (total and soluble fibre) of the tropical red algae Kappaphycus alvarezii , Kappaphycus striatus and Eucheuma…”
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Bile acids in laryngopharyngeal refluxate: Will they enhance or attenuate the action of pepsin? by Ali, Mahmoud S., Parikh, Shruti, Chater, Peter, Pearson, Jeffrey P.

“…Objectives/Hypothesis: To assess if, as previously reported in the literature, bile acids inhibit pepsin activity, resulting in pepsin having a less important…”
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ζ potential changing nanoparticles as cystic fibrosis transmembrane conductance regulator gene delivery system: an by Prüfert, Felix, Bonengel, Sonja, Köllner, Saskia, Griesser, Janine, Wilcox, Matthew D, Chater, Peter I, Pearson, Jeffrey P, Bernkop-Schnürch, Andreas

“…Aim of the study was the development of ζ potential changing nanoparticles as gene delivery system for the cystic fibrosis transmembrane conductance regulator…”
Get full text