Search Results - "Chatelain, C"

The family of K2P channels: salient structural and functional properties by Feliciangeli, Sylvain, Chatelain, Frank C., Bichet, Delphine, Lesage, Florian

“…Potassium channels participate in many biological functions, from ion homeostasis to generation and modulation of the electrical membrane potential. They are…”
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Finite-size scaling of the majority-voter model above the upper critical dimension by Chatelain, C.

“…The majority-voter model is studied by Monte Carlo simulations on hypercubic lattices of dimension d = 2 to 7 with periodic boundary conditions. The critical…”
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Physiological roles of heteromerization: focus on the two‐pore domain potassium channels by Khoubza, Lamyaa, Chatelain, Franck C., Feliciangeli, Sylvain, Lesage, Florian, Bichet, Delphine

“…Potassium channels form the largest family of ion channels with more than 80 members involved in cell excitability and signalling. Most of them exist as…”
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Mechanistic basis of the dynamic response of TWIK1 ionic selectivity to pH by Chatelain, Franck C., Gilbert, Nicolas, Bichet, Delphine, Jauch, Annaïse, Feliciangeli, Sylvain, Lesage, Florian, Bignucolo, Olivier

“…Highly selective for K + at neutral pH, the TWIK1 channel becomes permeable to Na + upon acidification. Using molecular dynamics simulations, we identify a…”
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Convergence of Multiple Stimuli to a Single Gate in TREK1 and TRAAK Potassium Channels by Choveau, Frank S, Ben Soussia, Ismail, Bichet, Delphine, Franck, Chatelain C., Feliciangeli, Sylvain, Lesage, Florian

“…Inhibitory potassium channels of the TREK1/TRAAK family are integrators of multiple stimuli, including temperature, membrane stretch, polyunsaturated fatty…”
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Polycystin-1 and -2 Dosage Regulates Pressure Sensing by Sharif-Naeini, Reza, Folgering, Joost H.A., Bichet, Delphine, Duprat, Fabrice, Lauritzen, Inger, Arhatte, Malika, Jodar, Martine, Dedman, Alexandra, Chatelain, Franck C., Schulte, Uwe, Retailleau, Kevin, Loufrani, Laurent, Patel, Amanda, Sachs, Frederick, Delmas, Patrick, Peters, Dorien J.M., Honoré, Eric

“…Autosomal-dominant polycystic kidney disease, the most frequent monogenic cause of kidney failure, is induced by mutations in the PKD1 or PKD2 genes, encoding…”
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Hyperscaling violation in the 2D 8-state Potts model with long-range correlated disorder by Chatelain, C.

“…The first-order phase transition of the two-dimensional eight-state Potts model is shown to be rounded when long-range correlated disorder is coupled to energy…”
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Emergence of microstructural patterns in skin cancer: a phase separation analysis in a binary mixture by Chatelain, C, Balois, T, Ciarletta, P, Ben Amar, M

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Contour instabilities in early tumor growth models by Ben Amar, M, Chatelain, C, Ciarletta, P

“…Recent tumor growth models are often based on the multiphase mixture framework. Using bifurcation theory techniques, we show that such models can give contour…”
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Factors predictive of leg‐ulcer healing in sickle cell disease: a multicentre, prospective cohort study by Senet, P., Blas‐Chatelain, C., Levy, P., Manea, E.M., Peschanski, M., Mirault, T., Stankovic‐Stojanovic, K., Debure, C., Debbache, K., Girot, R., Bureau, J.‐M., Bachmeyer, C., Baldeschi, C., Galacteros, F., Lionnet, F., Gellen‐Dautremer, J.

“…Summary Background Leg ulcers (LUs) are a chronic and severe complication of sickle cell disease (SCD). A prospective study in patients with SCD to identify…”
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Tandem Pore Domain Halothane-inhibited K+ Channel Subunits THIK1 and THIK2 Assemble and Form Active Channels by Blin, Sandy, Chatelain, Franck C., Feliciangeli, Sylvain, Kang, Dawon, Lesage, Florian, Bichet, Delphine

“…Despite a high level of sequence homology, tandem pore domain halothane-inhibited K+ channel 1 (THIK1) produces background K+ currents, whereas THIK2 is…”
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TWIK1, a unique background channel with variable ion selectivity by Chatelain, Franck C., Bichet, Delphine, Douguet, Dominique, Feliciangeli, Sylvain, Bendahhou, Saïd, Reichold, Markus, Warth, Richard, Barhanin, Jacques, Lesage, Florian

“…TWIK1 belongs to the family of background K⁺ channels with two pore domains. In native and transfected cells, TWIK1 is detected mainly in recycling endosomes…”
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Pre‐analytical issues in the measurement of circulating microparticles: current recommendations and pending questions by Mullier, F., Bailly, N., Chatelain, C., Chatelain, B., Dogné, J.‐M.

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Synthesis and structure–activity relationship study of substituted caffeate esters as antinociceptive agents modulating the TREK-1 channel by Rodrigues, Nuno, Bennis, Khalil, Vivier, Delphine, Pereira, Vanessa, C. Chatelain, Franck, Chapuy, Eric, Deokar, Hemantkumar, Busserolles, Jérôme, Lesage, Florian, Eschalier, Alain, Ducki, Sylvie

“…The TWIK-related K+ channel, TREK-1, has recently emerged as an attractive therapeutic target for the development of a novel class of analgesic drugs. It has…”
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Platelet microparticle generation assay: A valuable test for immune heparin-induced thrombocytopenia diagnosis by Mullier, F, Minet, V, Bailly, N, Devalet, B, Douxfils, J, Chatelain, C, Elalamy, I, Dogné, J.M, Chatelain, B

“…Abstract Background Early diagnosis of immune heparin-induced thrombocytopenia (HIT) is essential to improve clinical outcome but remains challenging. The…”
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Corrigendum: Convergence of Multiple Stimuli to a Single Gate in TREK1 and TRAAK Potassium Channels by Choveau, Frank S., Ben Soussia, Ismail, Bichet, Delphine, Chatelain, Franck C., Feliciangeli, Sylvain, Lesage, Florian

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3-D RPET-NET: Development of a 3-D PET Imaging Convolutional Neural Network for Radiomics Analysis and Outcome Prediction by Amyar, A., Ruan, S., Gardin, I., Chatelain, C., Decazes, P., Modzelewski, R.

“…Radiomics is now widely used to improve the prediction of treatment response and patient prognosis in oncology. In this paper, we propose an end-to-end…”
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Antagonistic Effect of a Cytoplasmic Domain on the Basal Activity of Polymodal Potassium Channels by Soussia, Ismail Ben, Choveau, Frank S, Blin, Sandy, Kim, Eun-Jin, Feliciangeli, Sylvain, Chatelain, Franck C, Kang, Dawon, Bichet, Delphine, Lesage, Florian

“…TREK/TRAAK channels are polymodal K channels that convert very diverse stimuli, including bioactive lipids, mechanical stretch and temperature, into electrical…”
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More on: calibration for the measurement of microparticles: needs, interests, and limitations of calibrated polystyrene beads for flow cytometry‐based quantification of biological microparticles by MULLIER, F., BAILLY, N., CHATELAIN, C., DOGNÉ, J. M., CHATELAIN, B.

“…See also Chandler WL, Yeung W, Tait JF. A new microparticle size calibration standard for use in measuring smaller microparticles using a new flow cytometer. J…”
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Silencing of the Tandem Pore Domain Halothane-inhibited K+ Channel 2 (THIK2) Relies on Combined Intracellular Retention and Low Intrinsic Activity at the Plasma Membrane by Chatelain, Franck C., Bichet, Delphine, Feliciangeli, Sylvain, Larroque, Marie-Madeleine, Braud, Véronique M., Douguet, Dominique, Lesage, Florian

“…The tandem pore domain halothane-inhibited K+ channel 1 (THIK1) produces background K+ currents. Despite 62% amino acid identity with THIK1, THIK2 is not…”
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