Search Results - "Chatchanok Udomtanakunchai"
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Pentagalloyl Glucose-Targeted Inhibition of P-Glycoprotein and Re-Sensitization of Multidrug-Resistant Leukemic Cells (K562/ADR) to Doxorubicin: In Silico and Functional Studies
Published in Pharmaceuticals (Basel, Switzerland) (22-08-2023)“…Combining phytochemicals with chemotherapeutic drugs has demonstrated the potential to surmount drug resistance. In this paper, we explore the efficacy of…”
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Late Effects of Low-Dose Radiation on the Bone Marrow, Lung, and Testis Collected From the Same Exposed BALB/cJ Mice
Published in Dose-response (01-10-2018)“…We used 3 biological metrics highly relevant to health risks, that is, cell death, inflammation, and global DNA methylation, to determine the late effects of…”
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3
Protein binding of 4-hydroxybenzoic acid and 4-hydroxy-3-methoxybenzoic acid to human serum albumin and their anti-proliferation on doxorubicin-sensitive and doxorubicin-resistant leukemia cells
Published in Toxicology reports (01-01-2021)“…[Display omitted] •4-HBA and VA could interact with HSA.•4-HBA and VA decreased K562 and K562/Dox cells viability.•These current studies could provide useful…”
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Modulation of p-glycoprotein-mediated efflux pirarubicin in living multidrug-resistant K562/Dox cell lines by 4-hydroxybenzoic acid and 4-hydroxy-3-methoxybenzoic acid via impairment of the cellular energetic state
Published in Toxicology reports (2022)“…The objective was to investigate the effect of 4-hydroxybenzoic acid (4-HBA) and 4-hydroxy-3-methoxybenzoic acid (Vanillic acid, VA) on p-glycoprotein (P-gp)…”
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Identification of Metabolic Phenotypes in Young Adults with Obesity by 1H NMR Metabolomics of Blood Serum
Published in Life (Basel, Switzerland) (18-06-2021)“…(1) Since the obesity prevalence rate has been consistently increasing, it is necessary to find an effective way to prevent and treat it. Although progress is…”
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Advanced Molecular Imaging (MRI/MRS/1H NMR) for Metabolic Information in Young Adults with Health Risk Obesity
Published in Life (Basel, Switzerland) (01-10-2021)“…Background: Obesity or being overweight is a medical condition of abnormal body fat accumulation which is associated with a higher risk of developing metabolic…”
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Influence of short-term iodinated radiographic contrast media exposure on reactive oxygen species levels in K562 cancer cells
Published in Journal of associated medical sciences (01-05-2019)“…Background: Iodinated radiographic contrast media (IRCM) are commonly used for evaluating cancer diseases in diagnostic radiology. There are several studies…”
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Visualization of Inflammation at Early Stage of Lung Cancer in Xenografted Temporally Immunosuppression Rats by Ferrioxamine Magnetic Resonance Imaging
Published in International Journal of Molecular Imaging (01-01-2016)“…Physiological responses such as chronic inflammation and angiogenesis could be used as biomarkers for early detection of cancer with noninvasive imaging…”
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The Effects of Iodinated Radiographic Contrast Media on Multidrug-resistant K562/Dox Cells: Mitochondria Impairment and P-glycoprotein Inhibition
Published in Cell biochemistry and biophysics (01-06-2019)“…Iodinated radiographic contrast media is used in cancer radiography for cancer diagnosis. The aim of this present study was to examine five iodinated…”
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Alternative X-ray attenuation material from iodide-starch-gel-based materials
Published in Journal of associated medical sciences (05-01-2025)“…Background: Iodine is often used as a contrast media because the k-shell binding energy (K-edge) is 33.2 keV, the average energy of a diagnostic X-ray. Thus,…”
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11
Decelerate amyloid fibrillation by the alkaloids extracted from Stephania venosa
Published in Journal of associated medical sciences (04-09-2023)“…Background: Naturally occurring phytochemical compounds have received considerable attention as alternative candidates for anti-amyloidogenic agents…”
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Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug resistance (MDR) modulators
Published in European journal of medicinal chemistry (15-06-2019)“…In this study, a new series of N,N-bis(alkanol)amine aryl ester heterodimers was synthesized and studied. The new compounds were designed based on the…”
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Effects of gadolinium-based magnetic resonance imaging contrast media on red blood cells and K562 cancer cells
Published in Journal of trace elements in medicine and biology (01-12-2020)“…Gadolinium-based contrast media (GBCM) are commonly used in diagnostic magnetic resonance imaging (MRI) in clinical applications. The objective of this study…”
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Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents
Published in European journal of medicinal chemistry (10-03-2018)“…A series of 1,4-substituted arylalkyl piperazine derivatives were synthesized and studied with the aim to obtain potent P-gp-dependent multidrug-resistant…”
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Effect of pre-low-dose irradiation on anticancer activities of gallic acid in leukemic K562 and K562/Dox cells: cell viability and cellular energetic state studies
Published in Medical oncology (Northwood, London, England) (29-09-2022)“…The aim of this study was to determine the effects of pre-low-dose irradiation followed by gallic acid (GA) on cell viability and cellular energetic state of…”
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Gallic acid enhances pirarubicin‑induced anticancer in living K562 and K562/Dox leukemia cancer cells through cellular energetic state impairment and P‑glycoprotein inhibition
Published in Oncology reports (01-10-2021)“…Leukemia is a common malignancy affecting humans worldwide. Pirarubicin (Pira) is one of the anticancer agents used for the treatment of leukemia. Although…”
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Influence of low-dose X-ray on plasma membrane properties of erythroleukemia cell lines (K562, K562/adr)
Published in Journal of associated medical sciences (02-01-2023)“…Background: Low-dose X-ray in medical use for diagnosis and therapy can result in cellular biology either directly or indirectly. In cell biology, the…”
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Different responses of normal cells (red blood cells) and cancer cells (K562 and K562/Dox cells) to low-dose 137Cs gamma-rays
Published in Molecular and clinical oncology (01-04-2021)“…High-dose radiation is deleterious to cells or tissues. However, the health risks of exposure to low-dose radiation remain unclear. The present study aimed to…”
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Different responses of normal cells (red blood cells) and cancer cells (K562 and K562/Dox cells) to low-dose 137 Cs gamma-rays
Published in Molecular and clinical oncology (01-04-2021)“…High-dose radiation is deleterious to cells or tissues. However, the health risks of exposure to low-dose radiation remain unclear. The present study aimed to…”
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In vitro evaluation of P-glycoprotein functions in human neuroblastoma cell lines
Published in Journal of associated medical sciences (01-02-2018)“…Background: Neuroblastoma (NB) remains one of the most puzzling of paediatric cancers in which most patients develop progressive disease that is refractory to…”
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