Search Results - "Chataway, J."
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Identifying barriers to help-seeking for sexual dysfunction in multiple sclerosis
Published in Journal of neurology (01-12-2018)“…Background Sexual dysfunction (SD) is common in multiple sclerosis (MS), however, under-reported. Objective The aim of this study was to identify barriers…”
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2017 McDonald diagnostic criteria: A review of the evidence
Published in Multiple sclerosis and related disorders (01-08-2018)“…•Multiple sclerosis is diagnosed according to the McDonald Criteria, recently revised in 2017.•Revisions are based on existing evidence, and not expert…”
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A practical approach to diagnosing adult onset leukodystrophies
Published in Journal of neurology, neurosurgery and psychiatry (01-07-2014)Get full text
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Sodium intake and multiple sclerosis activity and progression in BENEFIT
Published in Annals of neurology (01-07-2017)“…Objective To assess whether a high‐salt diet, as measured by urinary sodium concentration, is associated with faster conversion from clinically isolated…”
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Profiling cognitive–motor interference in a large sample of persons with progressive multiple sclerosis and impaired processing speed: results from the CogEx study
Published in Journal of neurology (01-06-2023)“…Background Performing cognitive–motor dual tasks (DTs) may result in reduced walking speed and cognitive performance. The effect in persons with progressive…”
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Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: An application in multiple sclerosis
Published in Statistics in medicine (15-06-2011)“…In recent years adaptive seamless phase II/III designs (ASDs) allowing treatment or dose selection at an interim analysis have gained much attention because of…”
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Serum Neurofilament Light concentrations are not associated with renal function in secondary progressive multiple sclerosis
Published in Biomarkers in neuropsychiatry (01-12-2021)“…Neurofilament Light (NFL) is a promising biomarker of neuroaxonal injury. Its utility may be improved by expression relative to age-matched controls and by…”
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NAA is a Marker of Disability in Secondary-Progressive MS: A Proton MR Spectroscopic Imaging Study
Published in American journal of neuroradiology : AJNR (01-12-2020)“…The secondary progressive phase of multiple sclerosis is characterised by disability progression due to processes that lead to neurodegeneration. Surrogate…”
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Lymphomatosis cerebri: a treatable cause of rapidly progressive dementia
Published in Journal of neurology, neurosurgery and psychiatry (01-02-2015)“…Cerebrospinal fluid (CSF) examination showed a protein level of 0.74 g/L with a glucose of 3.2 mmol/L (serum 5.5 mmol/L), <1 white blood cell per millilitre…”
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South Asian strokes: lessons from the St Mary's stroke database
Published in QJM : An International Journal of Medicine (01-01-2010)“…Background: South Asians comprise the largest ethnic minority population in the UK. This subgroup is known to have an elevated risk of stroke. However, there…”
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Human stem cell therapy in ischaemic stroke: a review
Published in Age and ageing (01-01-2011)“…Stroke is a leading cause of death and disability. Globally, 15 million people suffer a stroke each year, of whom more than 5 million die, and a further 5…”
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Associations between fatigue impact and physical and neurobehavioural factors: An exploration in people with progressive multiple sclerosis
Published in Multiple sclerosis and related disorders (01-10-2024)“…Fatigue is common in people with multiple sclerosis (MS). Understanding the relationship between fatigue, physical and neurobehavioural factors is important to…”
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It is better to be in a clinical trial than not: lessons learnt from clinical neurology—the management of acute multiple sclerosis relapses
Published in QJM : An International Journal of Medicine (01-08-2012)“…To compare being on-, or off-, a randomized controlled trial (RCT) for the same intervention. Cohort study. Ambulatory outpatient clinic in a clinical…”
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Validating the portal population of the United Kingdom Multiple Sclerosis Register
Published in Multiple sclerosis and related disorders (01-08-2018)“…•Validation of a self declared MS Population with a clinically diagnosed one.•We analysed the UK MS Register for a number of key characteristics. The internet…”
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Patient perspective on decisions to switch disease-modifying treatments in relapsing-remitting multiple sclerosis
Published in Multiple sclerosis and related disorders (01-11-2020)“…•Large cohorts of people with RRMS have now taken several Disease-Modifying Treatments.•Switching is a distinctive, rapid and emotional decision-making…”
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Negotiating the radiologically isolated syndrome
Published in British journal of hospital medicine (London, England : 2005) (01-10-2014)“…Multiple sclerosis, always challenging, hands down a particular gauntlet with the concept of the radiologically isolated syndrome. This article discusses what…”
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Testing for urinary tract colonization before high-dose corticosteroid treatment in acute multiple sclerosis relapses: prospective algorithm validation
Published in European journal of neurology (01-03-2013)“…Background and purpose To evaluate a dipstick algorithm for urinary tract colonization, prior to high‐dose corticosteroid treatment in acute relapses of…”
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A longitudinal study of MRI-detected atrophy in secondary progressive multiple sclerosis
Published in Journal of neurology (01-09-2010)“…MRI measures of tissue atrophy within the central nervous system may reflect the neurodegenerative process which underpins the progressive phase of multiple…”
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Longitudinal changes in magnetisation transfer ratio in secondary progressive multiple sclerosis: data from a randomised placebo controlled trial of lamotrigine
Published in Journal of neurology (01-03-2012)“…Sodium blockade with lamotrigine is neuroprotective in animal models of central nervous system demyelination. This study evaluated the effect of lamotrigine on…”
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Magnetic resonance imaging measures of brain and spinal cord atrophy correlate with clinical impairment in secondary progressive multiple sclerosis
Published in Multiple sclerosis (01-09-2008)“…Background Neuroaxonal loss is a pathological substrate of disability in progressive multiple sclerosis (MS) and can be estimated in vivo by measuring tissue…”
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