Search Results - "Chassaigne, M."

Multivariate analysis of determinants of bacterial contamination of whole-blood donations by Perez, P., Bruneau, C., Chassaigne, M., Salmi, L. R., Noel, L., Allouch, P., Audurier, A., Gulian, C., Janus, G., Boulard, G., De Micco, P.

“…Background and Objectives Introduction of bacteria into blood components at the collection stage seems to be a frequent occurrence. We therefore assessed…”
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Improved pharmacodynamics of L-asparaginase-loaded in human red blood cells by Kravtzoff, R, Desbois, I, Lamagnere, J P, Muh, J P, Valat, C, Chassaigne, M, Colombat, P, Ropars, C

“…To evaluate the modification of pharmacodynamic parameters induced by the administration of L-asparaginase loaded into red blood cells, 13 patients received a…”
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Engineered erythrocytes : influence of P50 rightward shift and oxemia on oxygen transport to tissues by ROPARS, C, CHASSAIGNE, M, AVENARD, G

“…The red blood cell (RBC) membrane may be reversibly opened using a lysis-resealing continuous flow method. The technology was adapted to the internalisation of…”
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Erythrocytes as carriers for L-asparaginase. Methodological and mouse in-vivo studies by Kravtzoff, R, Ropars, C, Laguerre, M, Muh, J P, Chassaigne, M

“…L-Asparaginase has been encapsulated in Swiss mouse or human erythrocytes by hypotonic haemolysis followed by isotonic resealing and reannealing. The details…”
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Tolerance evaluation of L-asparaginase loaded in red blood cells by KRAVTZOFF, R, COLOMBAT, P, CHASSAIGNE, M, ROPARS, C, DESBOIS, I, LINASSIER, C, MUH, J. P, PHILIP, T, BLAY, J. Y, GARDENBAS, M, POUMIER-GASCHARD, P, LAMAGNERE, J. P

“…A pilot clinical study was conducted to evaluate the toxicity of a single dose of L-asparaginase loaded in red blood cells (RBCs). Thirteen patients received a…”
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Reduction of bacterial load by predonation sampling by Chassaigne, M., Vassort-Bruneau, C., Allouch, P., Audurier, A., Boulard, G., Grosdhomme, F., Noel, L., Gulian, C., Janus, G., Perez, P.

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Internalization and distribution of inositol hexakisphosphate in red blood cells by Boucher, L, Chassaigne, M, Ropars, C

“…Inositol hexakisphosphate (InsP6), an allosteric effector of haemoglobin, is able to modify the oxyhaemoglobin dissociation curve. The rightwards shift of the…”
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Quality, ISO 9002 and haemapheresis service by Chassaigne, M, Desbois, I, Hérault, B, Gaschard, P

“…Hemotherapy in developed countries is safer than ever but the present perception of society seems different than in the past. As Isbister wrote, during recent…”
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Large-scale entrapment of drugs into resealed red blood cells using a continuous-flow dialysis system by Ropars, C, Avenard, G, Chassaigne, M

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Modification of partial pressure of oxygen (P50) in mammalian red blood cells by incorporation of an allosteric effector of hemoglobin by Bailleul, C, Borrelly-Villereal, M C, Chassaigne, M, Ropars, C

“…Internalization of inositol hexaphosphate (IHP) in mammalian red blood cells (RBC) produces a modification of the hemoglobin-oxygen affinity, leading to a…”
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Evaluation of doxorubicin in combination with mafosfamide for in vitro elimination of myeloid and lymphoid tumor cells from human bone marrow by Domenech, J, Georget, M T, Gihana, E, Colombat, P, Brémond, J L, Chassaigne, M, Lamagnère, J P, Binet, C

“…In an attempt to improve in vitro pharmacological purging of autologous grafts, the ability of doxorubicin (DOX), alone and in combination with mafosfamide…”
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Improved oxygen delivery to tissues and iron chelator transport through the use of lysed and resealed red blood cells: a new perspective on Cooley's anemia therapy by Ropars, C, Teisseire, B, Avenard, G, Chassaigne, M, Hurel, C, Girot, R, Nicolau, C

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Efficacy of a new collection procedure for preventing bacterial contamination of whole-blood donations by Bruneau, Cecile, Perez, Paul, Chassaigne, Maurice, Allouch, Pierre, Audurier, Andre, Gulian, Christine, Janus, Guy, Boulard, Gilbert, De Micco, Philippe, Salmi, L.R., Noel, Luc

“…BACKGROUND : Transfusion‐related bacterial contamination is a serious problem. The introduction of bacteria into donations at the collection stage seems…”
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Enhancement of P50 by inositol hexa phosphate entrapped in resealed erythrocytes in piglets by Teisseire, B, Ropars, C, Nicolau, C, Vallez, M O, Chassaigne, M

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Session 7 Infections bactériennes transfusionnelles by Chassaigne, M., Tardivel, R.

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Oxygen transport to tissue modified by entrapment of an allosteric effector of haemoglobin in erythrocytes by Villereal, M C, Ropars, C, Hurel, C, Teisseire, B, Chassaigne, M, Itti, R, Casset, D, Nicolau, C

“…Oxygen affinity of haemoglobin is modulated by several parameters such as the allosteric effector 2-3 DPG for most mammalians. Inositol hexaphosphate (I.H.P.)…”
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Thrombocytopenia in systemic lupus erythematosus: association with antiplatelet and anticardiolipin antibodies by Rupin, A, Gruel, Y, Poumier-Gaschard, P, Chassaigne, M, Leroy, J, Bardos, P

“…Serum platelet bindable immunoglobulin G (SPbIgG) and anticardiolipin antibodies (ACA) have been assayed in SLE patients with (group A, n = 8) and without…”
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Several aspects of red blood cell engineering: potential therapeutic applications by Bailleul, C, Kravtzoff, R, Chestier, N, Laguerre, M, Chassaigne, M, Ropars, C

“…Erythrocytes can be used to entrap drugs, enzymes or other molecules with active properties, with various encapsulation procedures. The method of…”
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Resealed red blood cells as a new blood transfusion product by Ropars, C, Chassaigne, M, Villereal, M C, Avenard, G, Hurel, C, Nicolau, C

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Engineered erythrocytes: influence of P sub(50) rightward shift and oxemia on oxygen transport to tissues by Ropars, C, Chassaigne, M, Avenard, G

“…The red blood cell (RBC) membrane may be reversibly opened using a lysis-resealing continuous flow method. The technology was adapted to the internalisation of…”
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