Search Results - "Chasela, Charles S"
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Maternal or Infant Antiretroviral Drugs to Reduce HIV-1 Transmission
Published in The New England journal of medicine (17-06-2010)“…Approximately 200,000 infants worldwide become infected with human immunodeficiency virus type 1 (HIV-1) annually through breast-feeding. In this randomized…”
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Thiamin and Riboflavin in Human Milk: Effects of Lipid-Based Nutrient Supplementation and Stage of Lactation on Vitamer Secretion and Contributions to Total Vitamin Content
Published in PloS one (17-02-2016)“…While thiamin and riboflavin in breast milk have been analyzed for over 50 years, less attention has been given to the different forms of each vitamin…”
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3
Maternal but Not Infant Anti-HIV-1 Neutralizing Antibody Response Associates with Enhanced Transmission and Infant Morbidity
Published in mBio (24-10-2017)“…A significant number of infants acquire HIV-1 through their infected mother's breast milk, primarily due to limited access to antiretrovirals. Passive…”
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4
Maternal and infant antiretroviral regimens to prevent postnatal HIV-1 transmission: 48-week follow-up of the BAN randomised controlled trial
Published in The Lancet (British edition) (30-06-2012)“…Summary Background In resource-limited settings where no safe alternative to breastfeeding exists, WHO recommends that antiretroviral prophylaxis be given to…”
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Treatment outcomes and costs of a simplified antiretroviral treatment strategy for hepatitis C among Hepatitis C Virus and Human Immuno deficiency Virus co‐infected patients in Ukraine
Published in JGH open (01-12-2022)“…Background and Aim To demonstrate the use of a standard dose of ledipasvir (LDV) and sofosbuvir (SOF), with or without ribavirin, to treat hepatitis C and…”
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Maternal and Breastmilk Viral Load: Impacts of Adherence on Peripartum HIV Infections Averted—The Breastfeeding, Antiretrovirals, and Nutrition Study
Published in Journal of acquired immune deficiency syndromes (1999) (15-12-2016)“…BACKGROUND:Antiretroviral (ARV) interventions are used to reduce HIV viral replication and prevent mother-to-child transmission. Viral suppression relies on…”
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Antiretroviral therapy provided to HIV-infected Malawian women in a randomized trial diminishes the positive effects of lipid-based nutrient supplements on breast-milk B vitamins
Published in The American journal of clinical nutrition (01-12-2015)“…Little information is available on B vitamin concentrations in human milk or on how they are affected by maternal B vitamin deficiencies, antiretroviral…”
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Determining the lower limit of detection required for HCV viral load assay for test of cure following direct‐acting antiviral‐based treatment regimens: Evidence from a global data set
Published in Journal of viral hepatitis (01-06-2022)“…Achieving global elimination of hepatitis C virus requires a substantial scale‐up of testing. Point‐of‐care HCV viral load assays are available as an…”
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Treatment outcomes and costs of a simplified antiviral treatment strategy for hepatitis C among monoinfected and HIV and/or hepatitis B virus‐co‐infected patients in Myanmar
Published in Journal of viral hepatitis (01-01-2021)“…Access to hepatitis C virus (HCV) testing and treatment is limited in Myanmar. We assessed an integrated HIV and viral hepatitis testing and HCV treatment…”
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Predictors of Perinatal HIV Transmission Among Women Without Prior Antiretroviral Therapy in a Resource-Limited Setting: The Breastfeeding, Antiretrovirals and Nutrition Study
Published in The Pediatric infectious disease journal (01-05-2019)“…BACKGROUND:To investigate potential risk factors for perinatal (intrauterine and intrapartum) mother-to-child transmission (MTCT) of HIV in women unexposed to…”
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Delayed HIV detection among infants exposed to postnatal antiretroviral prophylaxis during breastfeeding
Published in AIDS (London) (24-09-2015)“…OBJECTIVE:The objective of this study is to determine whether detection of HIV infection was delayed in infants exposed to antiretroviral prophylaxis to…”
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Impact of Daily Cotrimoxazole on Clinical Malaria and Asymptomatic Parasitemias in HIV-Exposed, Uninfected Infants
Published in Clinical infectious diseases (01-08-2015)“…Background. Cotrimoxazole preventive therapy (CPT) is recommended for all human immunodeficiency virus (HIV)–exposed infants to avoid opportunistic infections…”
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Hepatitis B virus infection among HIV-infected pregnant women in Malawi and transmission to infants
Published in Journal of hepatology (01-03-2014)“…Background & Aims The extent of HBV infection to infants of HBV/HIV-coinfected pregnant women in sub-Saharan Africa is unknown. The aim of this study was to…”
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Effects of concurrent exposure to antiretrovirals and cotrimoxazole prophylaxis among HIV-exposed, uninfected infants
Published in AIDS (London) (28-11-2017)“…BACKGROUND:Given the potential of Cotrimoxazole preventive therapy (CPT) to prevent bacterial and malarial infections in HIV exposed, uninfected (HEU) infants,…”
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Co-trimoxazole Prophylaxis, Asymptomatic Malaria Parasitemia, and Infectious Morbidity in Human Immunodeficiency Virus–Exposed, Uninfected Infants in Malawi: The BAN Study
Published in Clinical infectious diseases (15-08-2017)“…Background. Human immunodeficiency virus (HIV)–exposed infants are disproportionately at risk of morbidity and mortality compared with their HIV-unexposed…”
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Antiretroviral Drug Concentrations in Breastmilk, Maternal HIV Viral Load, and HIV Transmission to the Infant: Results From the BAN Study
Published in Journal of acquired immune deficiency syndromes (1999) (01-04-2019)“…BACKGROUND:Concentration of antiretroviral (ARV) drug found in plasma, and amounts of drug excreted into breastmilk, may affect HIV viral load and potentially…”
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Maternal and neonatal outcomes among women with HIV infection and their infants in Malawi
Published in International journal of gynecology and obstetrics (01-06-2017)“…Objective To describe maternal and neonatal morbidity and mortality among women with HIV infection and their infants. Methods A secondary analysis was…”
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Plasma and breast-milk selenium in HIV-infected Malawian mothers are positively associated with infant selenium status but are not associated with maternal supplementation: results of the Breastfeeding, Antiretrovirals, and Nutrition study
Published in The American journal of clinical nutrition (01-04-2014)“…Background: Selenium is found in soils and is essential for human antioxidant defense and immune function. In Malawi, low soil selenium and dietary intakes…”
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The effects of a lipid‐based nutrient supplement and antiretroviral therapy in a randomized controlled trial on iron, copper, and zinc in milk from HIV‐infected Malawian mothers and associations with maternal and infant biomarkers
Published in Maternal and child nutrition (01-04-2018)“…We evaluated effects of antiretroviral (ARV) therapy and lipid‐based nutrient supplements (LNSs) on iron, copper, and zinc in milk of exclusively breastfeeding…”
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Superior Uptake and Outcomes of Early Infant Diagnosis of HIV Services at an Immunization Clinic Versus an “Under-Five” General Pediatric Clinic in Malawi
Published in Journal of acquired immune deficiency syndromes (1999) (01-08-2012)“…OBJECTIVE:Although the Malawian government recommends HIV-exposed infants receive early infant diagnosis (EID) of HIV at “under-five” pediatric clinics (U5Cs),…”
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