Search Results - "Chase, P."

Fiber networks amplify active stress by Ronceray, Pierre, Broedersz, Chase P., Lenz, Martin

“…Large-scale force generation is essential for biological functions such as cell motility, embryonic development, and muscle contraction. In these processes,…”
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Molecular mechanisms underlying nucleotide repeat expansion disorders by Malik, Indranil, Kelley, Chase P., Wang, Eric T., Todd, Peter K.

“…The human genome contains over one million short tandem repeats. Expansion of a subset of these repeat tracts underlies over fifty human disorders, including…”
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Nonequilibrium Scaling Behavior in Driven Soft Biological Assemblies by Mura, Federica, Gradziuk, Grzegorz, Broedersz, Chase P

“…Measuring and quantifying nonequilibrium dynamics in active biological systems is a major challenge because of their intrinsic stochastic nature and the…”
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Cell contraction induces long-ranged stress stiffening in the extracellular matrix by Han, Yu Long, Ronceray, Pierre, Xu, Guoqiang, Malandrino, Andrea, Kamm, Roger D., Lenz, Martin, Broedersz, Chase P., Guo, Ming

“…Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of…”
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Microtubule-based transport is essential to distribute RNA and nascent protein in skeletal muscle by Denes, Lance T., Kelley, Chase P., Wang, Eric T.

“…While the importance of RNA localization in highly differentiated cells is well appreciated, basic principles of RNA localization in skeletal muscle remain…”
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Physical models of bacterial chromosomes by Harju, Janni, Broedersz, Chase P

“…The interplay between bacterial chromosome organization and functions such as transcription and replication can be studied in increasing detail using novel…”
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Inferring the Dynamics of Underdamped Stochastic Systems by Brückner, David B., Ronceray, Pierre, Broedersz, Chase P.

“…Many complex systems, ranging from migrating cells to animal groups, exhibit stochastic dynamics described by the underdamped Langevin equation. Inferring such…”
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Gut microbiome diversity is associated with sleep physiology in humans by Smith, Robert P, Easson, Cole, Lyle, Sarah M, Kapoor, Ritishka, Donnelly, Chase P, Davidson, Eileen J, Parikh, Esha, Lopez, Jose V, Tartar, Jaime L

“…The human gut microbiome can influence health through the brain-gut-microbiome axis. Growing evidence suggests that the gut microbiome can influence sleep…”
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Twenty-five years of nanoscale thermodynamics by Broedersz, Chase P., Ronceray, Pierre

“…A paper published in 1997 brought the thermodynamics of the nineteenth century into the twenty-first century — expanding the physics of transformations…”
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A Dynamic Situation with Uncertainty: Multiscale Modeling of Cardiac Thin-Filament Ca2+ Regulation by Chase, P. Bryant

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Broken detailed balance at mesoscopic scales in active biological systems by Battle, Christopher, Broedersz, Chase P., Fakhri, Nikta, Geyer, Veikko F., Howard, Jonathon, Schmidt, Christoph F., MacKintosh, Fred C.

“…Systems in thermodynamic equilibrium are not only characterized by time-independent macroscopic properties, but also satisfy the principle of detailed balance…”
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Criticality and isostaticity in fibre networks by Broedersz, Chase P., Mao, Xiaoming, Lubensky, Tom C., MacKintosh, Frederick C.

“…Disordered fibre networks are the basis of many man-made and natural materials, including structural components of living cells and tissue. The mechanical…”
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The Role of Liver Zonation in Physiology, Regeneration, and Disease by Panday, Regeant, Monckton, Chase P, Khetani, Salman R

“…As blood flows from the portal triad to the central vein, cell-mediated depletion establishes gradients of soluble factors such as oxygen, nutrients, and…”
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Ryanodine receptor‐associated myopathies: What's myosin got to do with it? by Chase, P. Bryant, Coons, Arianna N.

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Learning the non-equilibrium dynamics of Brownian movies by Gnesotto, Federico S., Gradziuk, Grzegorz, Ronceray, Pierre, Broedersz, Chase P.

“…Time-lapse microscopy imaging provides direct access to the dynamics of soft and living systems. At mesoscopic scales, such microscopy experiments reveal…”
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Learning the dynamics of cell–cell interactions in confined cell migration by Brückner, David B., Arlt, Nicolas, Fink, Alexandra, Ronceray, Pierre, Rädler, Joachim O., Broedersz, Chase P.

“…The migratory dynamics of cells in physiological processes, ranging from wound healing to cancer metastasis, rely on contactmediated cell–cell interactions…”
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Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy by Risi, Cristina M., Belknap, Betty, Atherton, Jennifer, Coscarella, Isabella Leite, White, Howard D., Bryant Chase, P., Pinto, Jose R., Galkin, Vitold E.

“…[Display omitted] •Thin filament troponin adopts multiple conformations at high and low Ca2+ levels.•The two strands of thin filament are structurally…”
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Elastic domains of giant proteins in striated muscle: Modeling compliance with rulers by Chase, P Bryant

“…Chase examines a study using the MUSICO model of striated muscle to evaluate the function of giant elastic proteins titin and nebulin…”
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Theory of Active Intracellular Transport by DNA Relaying by Hanauer, Christian, Bergeler, Silke, Frey, Erwin, Broedersz, Chase P.

“…The spatiotemporal organization of bacterial cells is crucial for the active segregation of replicating chromosomes. In several species, including Caulobacter…”
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Loop-extruders alter bacterial chromosome topology to direct entropic forces for segregation by Harju, Janni, van Teeseling, Muriel C. F., Broedersz, Chase P.

“…Entropic forces have been argued to drive bacterial chromosome segregation during replication. In many bacterial species, however, specifically evolved…”
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