Search Results - "Chartier, J."
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Separate and cumulative effects of adverse childhood experiences in predicting adult health and health care utilization
Published in Child abuse & neglect (01-06-2010)“…Abstract Objectives Objectives of this population-based study were: (1) to examine the relative contribution of childhood abuse and other adverse childhood…”
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2
Protein context shapes the specificity of SH3 domain-mediated interactions in vivo
Published in Nature communications (12-03-2021)“…Protein–protein interactions (PPIs) between modular binding domains and their target peptide motifs are thought to largely depend on the intrinsic binding…”
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3
MPZL1 forms a signalling complex with GRB2 adaptor and PTPN11 phosphatase in HER2-positive breast cancer cells
Published in Scientific reports (14-09-2017)“…HER2/ErbB2 is overexpressed in a significant fraction of breast tumours and is associated with a poor prognosis. The adaptor protein GRB2 interacts directly…”
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4
Proteomic Analysis of NCK1/2 Adaptors Uncovers Paralog-specific Interactions That Reveal a New Role for NCK2 in Cell Abscission During Cytokinesis
Published in Molecular & cellular proteomics (01-10-2018)“…Signals from cell surface receptors are often relayed via adaptor proteins. NCK1 and NCK2 are Src-Homology (SH) 2 and 3 domain adaptors that regulate processes…”
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5
Psychosocial and behavioral health indicators among immigrant and non-immigrant recent mothers
Published in BMC pregnancy and childbirth (26-08-2022)“…Abstract Background Perinatal risk factors can vary by immigration status. We examined psychosocial and behavioral perinatal health indicators according to…”
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6
Childhood Abuse, Adult Health, and Health Care Utilization: Results from a Representative Community Sample
Published in American journal of epidemiology (01-05-2007)“…The long-term consequences of childhood abuse on adult mental health have been a major focus of research. Much less attention has been directed to its effects…”
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7
Inequities in utilization of prenatal care: a population-based study in the Canadian province of Manitoba
Published in BMC pregnancy and childbirth (01-11-2018)“…Ensuring high quality and equitable maternity services is important to promote positive pregnancy outcomes. Despite a universal health care system, previous…”
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8
The Intersection between Criminal Accusations, Victimization, and Mental Disorders: A Canadian Population-Based Study
Published in Canadian journal of psychiatry (01-07-2020)“…Objective: Understand the relationship between criminal accusations, victimization, and mental disorders at a population level using administrative data from…”
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9
A bidirectional antagonism between aPKC and Yurt regulates epithelial cell polarity
Published in The Journal of cell biology (17-02-2014)“…During epithelial cell polarization, Yurt (Yrt) is initially confined to the lateral membrane and supports the stability of this membrane domain by repressing…”
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Evaluating the strengths and challenges of PAX dream makers approach to mental health promotion: perspectives of youth and community members in indigenous communities in Manitoba, Canada
Published in International journal of circumpolar health (31-12-2022)“…PAX Good Behaviour Game (PAX-GBG) is an evidence-based approach to co-create a nurturing environment where all children can thrive. This school-based approach…”
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11
Direct Phosphorylation of SRC Homology 3 Domains by Tyrosine Kinase Receptors Disassembles Ligand-Induced Signaling Networks
Published in Molecular cell (21-06-2018)“…Phosphotyrosine (pTyr) signaling has evolved into a key cell-to-cell communication system. Activated receptor tyrosine kinases (RTKs) initiate several…”
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12
Crumbs controls epithelial integrity by inhibiting Rac1 and PI3K
Published in Journal of cell science (15-10-2011)“…Drosophila Crumbs (Crb) and its mammalian ortholog CRB3 control epithelial polarity through poorly understood molecular mechanisms. Elucidating these…”
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13
Crumbs limits oxidase-dependent signaling to maintain epithelial integrity and prevent photoreceptor cell death
Published in The Journal of cell biology (17-09-2012)“…Drosophila melanogaster Crumbs (Crb) and its mammalian orthologues (CRB1-3) share evolutionarily conserved but poorly defined roles in regulating epithelial…”
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School personnel and community members' perspectives in implementing PAX good behaviour game in first nations grade 1 classrooms
Published in International journal of circumpolar health (01-01-2020)“…First Nations peoples in Canada have a history of poor mental health outcomes, as the result of colonisation and the legacy of residential schools. The PAX…”
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15
Prevalence, socio-demographic characteristics, and comorbid health conditions in pre-dialysis chronic kidney disease: results from the Manitoba chronic kidney disease cohort
Published in BMC nephrology (10-10-2018)“…Chronic Kidney Disease (CKD) is common and its prevalence has increased steadily over several decades. Monitoring of rates and severity of CKD across…”
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16
Sputum Autoantibodies in Patients With Established Rheumatoid Arthritis and Subjects at Risk of Future Clinically Apparent Disease
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-10-2013)“…Objective To evaluate the generation of rheumatoid arthritis (RA)–related autoantibodies in the lung. Methods Simultaneous collection of serum and induced…”
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Substrate-specific Interactions with the Heme-bound Oxygen Molecule of Nitric-oxide Synthase
Published in The Journal of biological chemistry (20-07-2007)“…We report the characterization by resonance Raman spectroscopy of the oxygenated complex (FeIIO2) of nitric-oxide synthases of Staphylococcus aureus (saNOS)…”
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18
Rac1 controls epithelial tube length through the apical secretion and polarity pathways
Published in Biology open (15-01-2016)“…The morphometric parameters of epithelial tubes are critical to the physiology and homeostasis of most organs. In addition, many human diseases are associated…”
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Monte-Carlo simulations of the new LNHB manganese bath facility
Published in Applied radiation and isotopes (01-04-2012)“…The new manganese bath facility of the Laboratoire National Henri Becquerel has been modeled by using three Monte-Carlo codes: MCNPX, GEANT4, and FLUKA, in…”
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A Direct-Interview Family Study of Generalized Social Phobia
Published in The American journal of psychiatry (01-01-1998)“…OBJECTIVE: The goal of this direct-interview family study was to replicate and extend an earlier finding of a familial liability for social phobia. The authors…”
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