Search Results - "Charrin, Benedicte C"

Histone Deacetylase 6 Inhibition Compensates for the Transport Deficit in Huntington's Disease by Increasing Tubulin Acetylation by Dompierre, Jim P, Godin, Juliette D, Charrin, Benedicte C, Cordelieres, Fabrice P, King, Stephen J, Humbert, Sandrine, Saudou, Frederic

“…A defect in microtubule (MT)-based transport contributes to the neuronal toxicity observed in Huntington's disease (HD). Histone deacetylase (HDAC) inhibitors…”
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Huntingtin Is Required for Mitotic Spindle Orientation and Mammalian Neurogenesis by Godin, Juliette D., Colombo, Kelly, Molina-Calavita, Maria, Keryer, Guy, Zala, Diana, Charrin, Bénédicte C., Dietrich, Paula, Volvert, Marie-Laure, Guillemot, François, Dragatsis, Ioannis, Bellaiche, Yohanns, Saudou, Frédéric, Nguyen, Laurent, Humbert, Sandrine

“…Huntingtin is the protein mutated in Huntington's disease, a devastating neurodegenerative disorder. We demonstrate here that huntingtin is essential to…”
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Huntingtin Controls Neurotrophic Support and Survival of Neurons by Enhancing BDNF Vesicular Transport along Microtubules by Gauthier, Laurent R, Charrin, Bénédicte C, Borrell-Pagès, Maria, Dompierre, Jim P, Rangone, Hélène, Cordelières, Fabrice P, De Mey, Jan, MacDonald, Marcy E, Leßmann, Volkmar, Humbert, Sandrine, Saudou, Frédéric

“…Polyglutamine expansion (polyQ) in the protein huntingtin is pathogenic and responsible for the neuronal toxicity associated with Huntington's disease (HD)…”
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Axonal transport failure in neurodegenerative disorders: the case of Huntington’s disease by Charrin, Bénédicte C., Saudou, Frédéric, Humbert, Sandrine

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