Search Results - "Charrier, Melinda"

Dendritic cell-derived exosomes as immunotherapies in the fight against cancer by Pitt, Jonathan M, Charrier, Mélinda, Viaud, Sophie, André, Fabrice, Besse, Benjamin, Chaput, Nathalie, Zitvogel, Laurence

“…Exosomes are nanometric membrane vesicles of late endosomal origin released by most, if not all, cell types as a means of sophisticated intercellular…”
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Automated Detection of Arm-Level Alterations for Individual Cancer Patients in the Clinical Setting by Christinat, Yann, Chaskar, Prasad, Clément, Sophie, Ho, Liza, Charrier, Mélinda, McKee, Thomas, Tsantoulis, Petros

“…Copy number alterations are genetic events that promote tumor initiation and progression and are used in clinical care as diagnostic, prognostic, and…”
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IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: implications for antimetastatic treatment by Desbois, Mélanie, Béal, Coralie, Charrier, Mélinda, Besse, Benjamin, Meurice, Guillaume, Cagnard, Nicolas, Jacques, Yannick, Béchard, David, Cassard, Lydie, Chaput, Nathalie

“…BackgroundAs the immune system is compromised in patients with cancer, therapeutic strategies to stimulate immunity appear promising, to avoid relapse and…”
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Colon Immune-Related Adverse Events: Anti-CTLA-4 and Anti-PD-1 Blockade Induce Distinct Immunopathological Entities by Coutzac, Clélia, Adam, Julien, Soularue, Emilie, Collins, Michael, Racine, Antoine, Mussini, Charlotte, Boselli, Lisa, Kamsukom, Nyam, Mateus, Christine, Charrier, Mélinda, Cassard, Lydie, Planchard, David, Ribrag, Vincent, Fizazi, Karim, Loriot, Yohann, Lepage, Patricia, Scoazec, Jean-Yves, Robert, Caroline, Carbonnel, Franck, Chaput, Nathalie

“…Abstract Background and Aim Immune checkpoint inhibitors targeting CTLA-4 and PD-1 improve survival in cancer patients but may induce immune-related adverse…”
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Quantitation of human herpesvirus-6A, -6B and -7 DNAs in whole blood, mononuclear and polymorphonuclear cell fractions from healthy blood donors by Géraudie, Bastien, Charrier, Mélinda, Bonnafous, Pascale, Heurté, Delphine, Desmonet, Marion, Bartoletti, Marc-Antoine, Penasse, Cécile, Agut, Henri, Gautheret-Dejean, Agnès

“…Abstract Background Diagnosis of human herpesvirus-6A (HHV-6A), -6B (HHV-6B) or -7 (HHV-7) infections is often based on the measure of viral load in blood…”
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Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC by Besse, Benjamin, Charrier, Mélinda, Lapierre, Valérie, Dansin, Eric, Lantz, Olivier, Planchard, David, Le Chevalier, Thierry, Livartoski, Alain, Barlesi, Fabrice, Laplanche, Agnès, Ploix, Stéphanie, Vimond, Nadège, Peguillet, Isabelle, Théry, Clotilde, Lacroix, Ludovic, Zoernig, Inka, Dhodapkar, Kavita, Dhodapkar, Madhav, Viaud, Sophie, Soria, Jean-Charles, Reiners, Katrin S., Pogge von Strandmann, Elke, Vély, Frédéric, Rusakiewicz, Sylvie, Eggermont, Alexander, Pitt, Jonathan M., Zitvogel, Laurence, Chaput, Nathalie

“…Dendritic cell-derived exosomes (Dex) are small extracellular vesicles secreted by viable dendritic cells. In the two phase-I trials that we conducted using…”
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Ovarian cancer with high-level focal ERBB2 amplification responds to trastuzumab and pertuzumab by Thouvenin, Laure, Charrier, Mélinda, Clement, Sophie, Christinat, Yann, Tille, Jean-Christophe, Frigeri, Mauro, Homicsko, Krisztian, Michielin, Olivier, Bodmer, Alexandre, Chappuis, Pierre O., McKee, Thomas A., Tsantoulis, Petros

“…•Trastuzumab monotherapy has limited efficacy in ovarian cancer.•The combination of trastuzumab and pertuzumab has not been studied adequately.•An…”
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Multilingual RECIST classification of radiology reports using supervised learning by Mottin, Luc, Goldman, Jean-Philippe, Jäggli, Christoph, Achermann, Rita, Gobeill, Julien, Knafou, Julien, Ehrsam, Julien, Wicky, Alexandre, Gérard, Camille L, Schwenk, Tanja, Charrier, Mélinda, Tsantoulis, Petros, Lovis, Christian, Leichtle, Alexander, Kiessling, Michael K, Michielin, Olivier, Pradervand, Sylvain, Foufi, Vasiliki, Ruch, Patrick

“…The objective of this study is the exploration of Artificial Intelligence and Natural Language Processing techniques to support the automatic assignment of the…”
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Association of the Lung Immune Prognostic Index With Immune Checkpoint Inhibitor Outcomes in Patients With Advanced Non-Small Cell Lung Cancer by Mezquita, Laura, Auclin, Edouard, Ferrara, Roberto, Charrier, Melinda, Remon, Jordi, Planchard, David, Ponce, Santiago, Ares, Luis Paz, Leroy, Laura, Audigier-Valette, Clarisse, Felip, Enriqueta, Zerón-Medina, Jorge, Garrido, Pilar, Brosseau, Solenn, Zalcman, Gérard, Mazieres, Julien, Caramela, Caroline, Lahmar, Jihene, Adam, Julien, Chaput, Nathalie, Soria, Jean Charles, Besse, Benjamin

“…Derived neutrophils/(leukocytes minus neutrophils) ratio (dNLR) and lactate dehydrogenase (LDH) level have been correlated with immune checkpoint inhibitor…”
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Predicting immunotherapy outcomes under therapy in patients with advanced NSCLC using dNLR and its early dynamics by Mezquita, Laura, Preeshagul, Isabel, Auclin, Edouard, Saravia, Diana, Hendriks, Lizza, Rizvi, Hira, Park, Wungki, Nadal, Ernest, Martin-Romano, Patricia, Ruffinelli, Jose C., Ponce, Santiago, Audigier-Valette, Clarisse, Carnio, Simona, Blanc-Durand, Felix, Bironzo, Paolo, Tabbò, Fabrizio, Reale, Maria Lucia, Novello, Silvia, Hellmann, Matthew D., Sawan, Peter, Girshman, Jeffrey, Plodkowski, Andrew J., Zalcman, Gerard, Majem, Margarita, Charrier, Melinda, Naigeon, Marie, Rossoni, Caroline, Mariniello, AnnaPaola, Paz-Ares, Luis, Dingemans, Anne Marie, Planchard, David, Cozic, Nathalie, Cassard, Lydie, Lopes, Gilberto, Chaput, Nathalie, Arbour, Kathryn, Besse, Benjamin

“…dNLR at the baseline (B), defined by neutrophils/[leucocytes-neutrophils], correlates with immune-checkpoint inhibitor (ICI) outcomes in advanced…”
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Durable response to palbociclib and letrozole in ovarian cancer with CDKN2A loss by Frisone, Daniele, Charrier, Melinda, Clement, Sophie, Christinat, Yann, Thouvenin, Laure, Homicsko, Krisztian, Michielin, Olivier, Bodmer, Alexandre, Chappuis, Pierre O, McKee, Thomas A, Tsantoulis, Petros

“…Alterations of the Retinoblastoma (Rb) pathway are frequent in ovarian cancer, typically resulting from down-regulation, amplification, amplification, and…”
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Baseline-derived neutrophil-to-lymphocyte ratio (dNLR) and lactate dehydrogenase (LDH) to predict the benefit of immune checkpoint inhibitors (ICI) in advanced non-small cell lung cancer (NSCLC) patients by Mezquita, Laura, Auclin, Edouard, Ferrara, Roberto, Audigier-Valette, Clarisse, Tessonnier, Laurent, Charrier, Melinda, Boucher, Marie Eve, Lahmar, Jihene, Caramella, Caroline, Remon, Jordi, Planchard, David, Adam, Julien, Gazzah, Anas, Chaput, Nathalie, Soria, Jean-Charles, Besse, Benjamin

“…Abstract only 9089 Background: dNRL (Neutrophils/Leucocytes-Neutrophils) and LDH were recently correlated to ICI benefit in melanoma. We tested if dNLR and LDH…”
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Prognostic value of HLA-A2 status in advanced non-small cell lung cancer patients by Mezquita, Laura, Charrier, Melinda, Faivre, Laura, Dupraz, Louise, Lueza, Béranger, Remon, Jordi, Planchard, David, Bluthgen, Maria Virginia, Facchinetti, Francesco, Rahal, Arslane, Polo, Valentina, Gazzah, Anas, Caramella, Caroline, Adam, Julien, Pignon, Jean Pierre, Soria, Jean-Charles, Chaput, Nathalie, Besse, Benjamin

“…•HLA-A2 was positive in 48% of the patients, consistent with previous studies.•No association between HLA-A2 and patient or tumor characteristics.•No…”
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Durable response to palbociclib and letrozole in ovarian cancer with CDKN2A loss by Frisone, Daniele, Charrier, Melinda, Clement, Sophie, Christinat, Yann, Thouvenin, Laure, Homicsko, Krisztian, Michielin, Olivier, Bodmer, Alexandre, Chappuis, Pierre O., McKee, Thomas A., Tsantoulis, Petros

“…Alterations of the Retinoblastoma (Rb) pathway are frequent in ovarian cancer, typically resulting from CDKN2A down-regulation, CCNE1 amplification, CCND1/2…”
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