Search Results - "Charrier, Cécile"

Molecular mechanisms of the specialization of human synapses in the neocortex by Christopoulou, Eirini, Charrier, Cécile

“…Synapses of the neocortex specialized during human evolution to develop over extended timescales, process vast amounts of information and increase…”
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Trans-synaptic interactions of ionotropic glutamate receptors by Fossati, Matteo, Charrier, Cécile

“…•Most iGluRs engage in extracellular and trans-synaptic interactions.•iGluR trans-synaptic interactions specify the formation of synaptic connections.•GluD1…”
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Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons by Fossati, Matteo, Assendorp, Nora, Gemin, Olivier, Colasse, Sabrina, Dingli, Florent, Arras, Guillaume, Loew, Damarys, Charrier, Cécile

“…Fine orchestration of excitatory and inhibitory synaptic development is required for normal brain function, and alterations may cause neurodevelopmental…”
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SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses by Fossati, Matteo, Pizzarelli, Rocco, Schmidt, Ewoud R., Kupferman, Justine V., Stroebel, David, Polleux, Franck, Charrier, Cécile

“…The proper function of neural circuits requires spatially and temporally balanced development of excitatory and inhibitory synapses. However, the molecular…”
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Inhibition of SRGAP2 Function by Its Human-Specific Paralogs Induces Neoteny during Spine Maturation by Charrier, Cécile, Joshi, Kaumudi, Coutinho-Budd, Jaeda, Kim, Ji-Eun, Lambert, Nelle, de Marchena, Jacqueline, Jin, Wei-Lin, Vanderhaeghen, Pierre, Ghosh, Anirvan, Sassa, Takayuki, Polleux, Franck

“…Structural genomic variations represent a major driving force of evolution, and a burst of large segmental gene duplications occurred in the human lineage…”
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Unique properties of dually innervated dendritic spines in pyramidal neurons of the somatosensory cortex uncovered by 3D correlative light and electron microscopy by Gemin, Olivier, Serna, Pablo, Zamith, Joseph, Assendorp, Nora, Fossati, Matteo, Rostaing, Philippe, Triller, Antoine, Charrier, Cécile

“…Pyramidal neurons (PNs) are covered by thousands of dendritic spines receiving excitatory synaptic inputs. The ultrastructure of dendritic spines shapes signal…”
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CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny by Assendorp, Nora, Fossati, Matteo, Libé-Philippot, Baptiste, Christopoulou, Eirini, Depp, Marine, Rapone, Roberta, Dingli, Florent, Loew, Damarys, Vanderhaeghen, Pierre, Charrier, Cécile

“…Human-specific genes are potential drivers of brain evolution. Among them, SRGAP2C has contributed to the emergence of features characterizing human cortical…”
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Homeostatic Regulation of Synaptic GlyR Numbers Driven by Lateral Diffusion by Lévi, Sabine, Schweizer, Claude, Bannai, Hiroko, Pascual, Olivier, Charrier, Cécile, Triller, Antoine

“…In the spinal cord, most inhibitory synapses have a mixed glycine-GABA phenotype. Using a pharmacological approach, we report an NMDAR activity-dependent…”
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Emerging Mechanisms Underlying Dynamics of GABAergic Synapses by Maffei, Arianna, Charrier, Cécile, Caiati, Maddalena Delma, Barberis, Andrea, Mahadevan, Vivek, Woodin, Melanie A, Tyagarajan, Shiva K

“…Inhibitory circuits are diverse, yet with a poorly understood cell biology. Functional characterization of distinct inhibitory neuron subtypes has not been…”
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A crosstalk between β1 and β3 integrins controls glycine receptor and gephyrin trafficking at synapses by Triller, Antoine, Charrier, Cécile, Machado, Patricia, Tweedie-Cullen, Ry Y, Rutishauser, Dorothea, Mansuy, Isabelle M

“…Integrins connect cells to the extracellular matrix and mediate neuron-neuron or neuron-glia interactions during synapse maturation and synaptic plasticity…”
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GluD1 binds GABA and controls inhibitory plasticity by Piot, Laura, Heroven, Christina, Bossi, Simon, Zamith, Joseph, Malinauskas, Tomas, Johnson, Chris, Wennagel, Doris, Stroebel, David, Charrier, Cécile, Aricescu, A Radu, Mony, Laetitia, Paoletti, Pierre

“…Fast synaptic neurotransmission in the vertebrate central nervous system relies primarily on ionotropic glutamate receptors (iGluRs), which drive neuronal…”
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Cytoskeleton Regulation of Glycine Receptor Number at Synapses and Diffusion in the Plasma Membrane by Charrier, Cecile, Ehrensperger, Marie-Virginie, Dahan, Maxime, Levi, Sabine, Triller, Antoine

“…Lateral diffusion of neurotransmitter receptors in and out of synapses has been postulated as a core mechanism for rapid changes in receptor number at synapses…”
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Exploration de l’imaginaire des professeurs des écoles : repères méthodologiques by Charrier, Marie Cécile, Bergier, Bertrand

“…Cet article présente les fondements épistémologiques et méthodologiques d’une recherche en sciences de l’éducation, dont le but est l’exploration de…”
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How human-specific SRGAP2 gene duplications control human brain development by Charrier, Cécile, Polleux, Franck

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Exploration de l’imaginaire des professeurs des écoles: repères méthodologiques by Marie-Cécile Charrier, Bertrand Bergier

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ISDN2012_0241: Developmental and evolutionary functions of a human‐specific gene duplication of srGAP2 during brain development by Charrier, Cécile, Joshi, Kaumudi, Sassa, Takayuki, Coutinho‐Budd, Jaeda, Lambert, Nelle, Vanderhaegen, Pierre, Polleux, Franck

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Developmental and evolutionary functions of a human-specific gene duplication of srGAP2 during brain development by Charrier, Cécile, Joshi, Kaumudi, Sassa, Takayuki, Coutinho-Budd, Jaeda, Lambert, Nelle, Vanderhaegen, Pierre, Polleux, Franck

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A crosstalk between [beta]1 and [beta]3 integrins controls glycine receptor and gephyrin trafficking at synapses by Charrier, Cécile, Machado, Patricia, Tweedie-cullen, Ry Y, Rutishauser, Dorothea, Mansuy, Isabelle M, Triller, Antoine

“…The regulation of glycine receptor (GlyR) number at synapses is necessary for the efficacy of inhibition and the control of neuronal excitability in the spinal…”
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A crosstalk between β1 and β3 integrins controls glycine receptor and gephyrin trafficking at inhibitory synapses by Charrier, Cécile, Machado, Patricia, Tweedie-Cullen, Ry Yves, Mansuy, Isabelle M., Triller, Antoine

“…The regulation of glycine receptor (GlyR) number at synapses is fundamental for the efficacy of inhibition and the control of neuronal excitability in the…”
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A crosstalk between beta 1 and beta 3 integrins controls glycine receptor and gephyrin trafficking at synapses by Charrier, Cecile, Machado, Patricia, Tweedie-Cullen, Ry Y, Rutishauser, Dorothea, Mansuy, Isabelle M, Triller, Antoine

“…The regulation of glycine receptor (GlyR) number at synapses is necessary for the efficacy of inhibition and the control of neuronal excitability in the spinal…”
Get full text