Search Results - "Charrière, M"
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Protrusion force microscopy reveals oscillatory force generation and mechanosensing activity of human macrophage podosomes
Published in Nature communications (11-11-2014)“…Podosomes are adhesion structures formed in monocyte-derived cells. They are F-actin-rich columns perpendicular to the substrate surrounded by a ring of…”
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Dynamics of podosome stiffness revealed by atomic force microscopy
Published in Proceedings of the National Academy of Sciences - PNAS (07-12-2010)“…Podosomes are unique cellular entities specifically found in macrophages and involved in cell—matrix interactions, matrix degradation, and 3D migration. They…”
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Immune-suppression by OsHV-1 viral infection causes fatal bacteraemia in Pacific oysters
Published in Nature communications (11-10-2018)“…Infectious diseases are mostly explored using reductionist approaches despite repeated evidence showing them to be strongly influenced by numerous interacting…”
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The new insights into the oyster antimicrobial defense: Cellular, molecular and genetic view
Published in Fish & shellfish immunology (01-09-2015)“…Oysters are sessile filter feeders that live in close association with abundant and diverse communities of microorganisms that form the oyster microbiota. In…”
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Vibrio–bivalve interactions in health and disease
Published in Environmental microbiology (01-10-2020)“…Summary In the marine environment, bivalve mollusks constitute habitats for bacteria of the Vibrionaceae family. Vibrios belong to the microbiota of healthy…”
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Vibrio splendidus O‐antigen structure: a trade‐off between virulence to oysters and resistance to grazers
Published in Environmental microbiology (01-10-2020)“…Summary A major debate in evolutionary biology is whether virulence is maintained as an adaptive trait and/or evolves to non‐virulence. In the environment,…”
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Extracellular proteolysis in macrophage migration: Losing grip for a breakthrough
Published in European journal of immunology (01-10-2011)“…Macrophage tissue infiltration is a hallmark of several pathological situations including cancer, neurodegenerative disorders and chronic inflammation. Hence,…”
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Traits of a mussel transmissible cancer are reminiscent of a parasitic life style
Published in Scientific reports (16-12-2021)“…Some cancers have evolved the ability to spread from host to host by transmission of cancerous cells. These rare biological entities can be considered…”
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Outer membrane vesicles are vehicles for the delivery of Vibrio tasmaniensis virulence factors to oyster immune cells
Published in Environmental microbiology (01-04-2015)“…Summary Vibrio tasmaniensis LGP32, a facultative intracellular pathogen of oyster haemocytes, was shown here to release outer membrane vesicles (OMVs) both in…”
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Species-specific mechanisms of cytotoxicity toward immune cells determine the successful outcome of Vibrio infections
Published in Proceedings of the National Academy of Sciences - PNAS (09-07-2019)“…Vibrio species cause infectious diseases in humans and animals, but they can also live as commensals within their host tissues. How Vibrio subverts the host…”
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Antimicrobial histones and DNA traps in invertebrate immunity: evidences in Crassostrea gigas
Published in The Journal of biological chemistry (05-09-2014)“…Although antimicrobial histones have been isolated from multiple metazoan species, their role in host defense has long remained unanswered. We found here that…”
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Prevalence and polymorphism of a mussel transmissible cancer in Europe
Published in Molecular ecology (01-02-2022)“…Transmissible cancers are parasitic malignant cell lineages that have acquired the ability to infect new hosts from the same species, or sometimes related…”
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Macrophage podosomes go 3D
Published in European journal of cell biology (01-02-2011)“…Macrophage tissue infiltration is a critical step in the immune response against microorganisms and is also associated with disease progression in chronic…”
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Cooperation and cheating orchestrate Vibrio assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus
Published in Proceedings of the National Academy of Sciences - PNAS (03-10-2023)“…Polymicrobial infections threaten the health of humans and animals but remain understudied in natural systems. We recently described the Pacific Oyster…”
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Emergence and clonal expansion of Vibrio aestuarianus lineages pathogenic for oysters in Europe
Published in Molecular ecology (01-06-2023)“…Crassostrea gigas oysters represent a significant global food source with 4.7 million tons harvested per year. In 2001, the bacterium Vibrio aestuarianus…”
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Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota
Published in Marine drugs (26-11-2022)“…Big defensins are two-domain antimicrobial peptides (AMPs) that have highly diversified in mollusks. -BigDefs are expressed by immune cells in the oyster , and…”
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Taking Advantage of Electric Field Induced Bacterial Aggregation for the Study of Interactions between Bacteria and Macromolecules by Capillary Electrophoresis
Published in Analytical chemistry (Washington) (07-07-2015)“…The quantification of interaction stoichiometry and binding constant between bacteria (or other microorganism) and (macro)molecules remains a challenging…”
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Copper homeostasis at the host vibrio interface: lessons from intracellular vibrio transcriptomics
Published in Environmental microbiology (01-03-2016)“…Recent studies revealed that several vibrio species have evolved the capacity to survive inside host cells. However, it is still often ignored if intracellular…”
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Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians
Published in Open biology (11-10-2023)“…Transmissible cancer cell lines are rare biological entities giving rise to diseases at the crossroads of cancer and parasitic diseases. These malignant cells…”
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Resistance of the oyster pathogen Vibrio tasmaniensis LGP32 against grazing by Vannella sp. marine amoeba involves Vsm and CopA virulence factors
Published in Environmental microbiology (01-10-2020)“…Summary Vibrios are ubiquitous in marine environments and opportunistically colonize a broad range of hosts. Strains of Vibrio tasmaniensis present in oyster…”
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