Search Results - "Charney, D S"

Ketamine for rapid reduction of suicidal ideation: a randomized controlled trial by Murrough, J W, Soleimani, L, DeWilde, K E, Collins, K A, Lapidus, K A, Iacoviello, B M, Lener, M, Kautz, M, Kim, J, Stern, J B, Price, R B, Perez, A M, Brallier, J W, Rodriguez, G J, Goodman, W K, Iosifescu, D V, Charney, D S

“…Suicide is a devastating public health problem and very few biological treatments have been found to be effective for quickly reducing the intensity of…”
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Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome by Kiraly, D D, Horn, S R, Van Dam, N T, Costi, S, Schwartz, J, Kim-Schulze, S, Patel, M, Hodes, G E, Russo, S J, Merad, M, Iosifescu, D V, Charney, D S, Murrough, J W

“…A subset of patients with depression have elevated levels of inflammatory cytokines, and some studies demonstrate interaction between inflammatory factors and…”
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Neuroanatomical circuits modulating fear and anxiety behaviors by Charney, D. S.

“…Objective:  Our understanding of the neurobiology of anxiety disorders, although not complete, has advanced significantly with the development and application…”
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Plasma brain derived neurotrophic factor (BDNF) and response to ketamine in treatment-resistant depression by Haile, C. N., Murrough, J. W., Iosifescu, D. V., Chang, L. C., Al Jurdi, R. K., Foulkes, A., Iqbal, S., Mahoney, J. J., De La Garza, R., Charney, D. S., Newton, T. F., Mathew, S. J.

“…Ketamine produces rapid antidepressant effects in treatment-resistant depression (TRD), but the magnitude of response varies considerably between individual…”
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Psychobiological mechanisms of resilience: relevance to prevention and treatment of stress-related psychopathology by Haglund, M E M, Nestadt, P S, Cooper, N S, Southwick, S M, Charney, D S

“…Resilience refers to the ability to successfully adapt to stressors, maintaining psychological well-being in the face of adversity. Recent years have seen a…”
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Cognitive control of attention is differentially affected in trauma-exposed individuals with and without post-traumatic stress disorder by Blair, K S, Vythilingam, M, Crowe, S L, McCaffrey, D E, Ng, P, Wu, C C, Scaramozza, M, Mondillo, K, Pine, D S, Charney, D S, Blair, R J R

“…This study aimed to determine whether patients with post-traumatic stress disorder (PTSD) show difficulty in recruitment of the regions of the frontal and…”
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Battlefield-like stress following simulated combat and suppression of attention bias to threat by Wald, I, Lubin, G, Holoshitz, Y, Muller, D, Fruchter, E, Pine, D S, Charney, D S, Bar-Haim, Y

“…Acute stress disorder involves prominent symptoms of threat avoidance. Preliminary cross-sectional data suggest that such threat-avoidance symptoms may also…”
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Antidepressant effects of ketamine in depressed patients by Berman, Robert M, Cappiello, Angela, Anand, Amit, Oren, Dan A, Heninger, George R, Charney, Dennis S, Krystal, John H

“…Background: A growing body of preclinical research suggests that brain glutamate systems may be involved in the pathophysiology of major depression and the…”
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Biased emotional attention in post-traumatic stress disorder: a help as well as a hindrance? by Vythilingam, M, Blair, K S, McCaffrey, D, Scaramozza, M, Jones, M, Nakic, M, Mondillo, K, Hadd, K, Bonne, O, Mitchell, D G V, Pine, D S, Charney, D S, Blair, R J R

“…From a cognitive neuroscience perspective, the emotional attentional bias in post-traumatic stress disorder (PTSD) could be conceptualized either as emotional…”
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Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments by Krystal, J H, Sanacora, G, Blumberg, H, Anand, A, Charney, D S, Marek, G, Epperson, C N, Goddard, A, Mason, G F

“…Glutamate and gamma-amino butyric acid (GABA) systems are emerging as targets for development of medications for mood disorders. There is increasing…”
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The MCP-4/MCP-1 ratio in plasma is a candidate circadian biomarker for chronic post-traumatic stress disorder by Dalgard, C, Eidelman, O, Jozwik, C, Olsen, C H, Srivastava, M, Biswas, R, Eudy, Y, Rothwell, S W, Mueller, G P, Yuan, P, Drevets, W C, Manji, H K, Vythlingam, M, Charney, D S, Neumeister, A, Ursano, R J, Jacobowitz, D M, Pollard, H B, Bonne, O

“…Post-traumatic stress disorder (PTSD) is psychiatric disease, which can occur following exposure to traumatic events. PTSD may be acute or chronic, and can…”
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Hippocampal Volume Reduction in Major Depression by Bremner, J. Douglas, Narayan, Meena, Anderson, Eric R., Staib, Lawrence H., Miller, Helen L., Charney, Dennis S.

“…OBJECTIVE: Elevated levels of glucocorticoids in depression have been hypothesized to be associated with damage to the hippocampus, a brain area involved in…”
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Neural Correlates of Memories of Childhood Sexual Abuse in Women With and Without Posttraumatic Stress Disorder by Bremner, J. Douglas, Narayan, Meena, Staib, Lawrence H., Southwick, Steven M., McGlashan, Thomas, Charney, Dennis S.

“…OBJECTIVE: Childhood sexual abuse is very common in our society, but little is known about the long-term effects of abuse on brain function. The purpose of…”
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Neural correlates of exposure to traumatic pictures and sound in Vietnam combat veterans with and without posttraumatic stress disorder: a positron emission tomography study by Bremner, J.Douglas, Staib, Lawrence H, Kaloupek, Danny, Southwick, Steven M, Soufer, Robert, Charney, Dennis S

“…Background: Patients with posttraumatic stress disorder (PTSD) show a reliable increase in PTSD symptoms and physiological reactivity following exposure to…”
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Increased Striatal Dopamine Transmission in Schizophrenia: Confirmation in a Second Cohort by Abi-Dargham, Anissa, Gil, Roberto, Krystal, John, Baldwin, Ronald M., Seibyl, John P., Bowers, Malcom, van Dyck, Christopher H., Charney, Dennis S., Innis, Robert B., Laruelle, Marc

“…OBJECTIVE: The authors previously observed an increase in striatal dopamine transmission following amphetamine challenge in 15 untreated patients with…”
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[123I]β/CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease by MAREK, K. L, SEIBYL, J. P, ZOGHBI, S. S, ZEA-PONCE, Y, BALDWIN, R. M, FUSSELL, B, CHARNEY, D. S, VAN DYCK, C, HOFFER, P. B, INNIS, R. B

“…We have used in vivo single-photon emission computed tomography (SPECT) of the dopamine transporter with 2 beta-carboxymethoxy-3 beta-(4-iodophenyl)tropane…”
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Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease by Seibyl, J P, Marek, K L, Quinlan, D, Sheff, K, Zoghbi, S, Zea-Ponce, Y, Baldwin, R M, Fussell, B, Smith, E O, Charney, D S, van Dyck, C

“…Previous studies have utilized single-photon emission computed tomography (SPECT) to demonstrate decreased [123I]beta-CIT striatal uptake in idiopathic…”
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Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report by Bremner, J. Douglas, Randall, Penny, Vermetten, Eric, Staib, Lawrence, Bronen, Richard A., Mazure, Carolyn, Capelli, Sandi, McCarthy, Gregory, Innis, Robert B., Charney, Dennis S.

“…We have previously reported smaller hippocampal volume and deficits in short-term memory in patients with combat-related posttraumatic stress disorder (PTSD)…”
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Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder by BREMNER, J. D, LICINIO, J, DARNELL, A, KRYSTAL, J. H, OWENS, M. J, SOUTHWICK, S. M, NEMEROFF, C. B, CHARNEY, D. S

“…OBJECTIVE: Corticotropin-releasing factor (CRF) and somatostatin both play important roles in mediating responses to acute and chronic stress. The purpose of…”
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Single Photon Emission Computerized Tomography Imaging of Amphetamine-Induced Dopamine Release in Drug-Free Schizophrenic Subjects by Laruelle, Marc, Abi-Dargham, Anissa, Van Dyck, Christopher H., Gil, Roberto, D'Souza, Cyril D., Erdos, Joseph, McCance, Elinore, Rosenblatt, William, Fingado, Christine, Zoghbi, Sami S., Baldwin, Ronald M., Seibyl, John P., Krystal, John H., Charney, Dennis S., Innis, Robert B.

“…The dopamine hypothesis of schizophrenia proposes that hyperactivity of dopaminergic transmission is associated with this illness, but direct observation of…”
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