Search Results - "Charman, Robert J."

Single molecule iSCAT imaging reveals a fast, energy efficient search mode for the DNA repair protein UvrA by Charman, Robert J, Kad, Neil M

“…Exposure to UV radiation results in numerous DNA lesions, which threaten genome integrity. The nucleotide excision DNA repair pathway detects and repairs a…”
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Identification of a novel DNA repair inhibitor using an in silico driven approach shows effective combinatorial activity with genotoxic agents against multidrug‐resistant Escherichia coli by Bernacchia, Lorenzo, Paris, Antoine, Gupta, Arya, Charman, Robert J., McGreig, Jake, Wass, Mark N., Kad, Neil M.

“…Increasing antimicrobial drug resistance represents a global existential threat. Infection is a particular problem in immunocompromised individuals, such as…”
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DNA-Protein Interactions Studied Directly Using iSCAT Imaging of GNP-Tagged Proteins by Charman, Robert J, Kad, Neil M

“…Many protein interactions with DNA are reliant on the presence of specific DNA sequences, adducts, or structures. In bulk-phase experiments such DNA features…”
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