Search Results - "Charlton, Peter"

Modeling arterial pulse waves in healthy aging: a database for in silico evaluation of hemodynamics and pulse wave indexes by Charlton, Peter H, Mariscal Harana, Jorge, Vennin, Samuel, Li, Ye, Chowienczyk, Phil, Alastruey, Jordi

“…The arterial pulse wave (PW) is a rich source of information on cardiovascular (CV) health. It is widely measured by both consumer and clinical devices…”
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Toward a Robust Estimation of Respiratory Rate From Pulse Oximeters by Pimentel, Marco A. F., Johnson, Alistair E. W., Charlton, Peter H., Birrenkott, Drew, Watkinson, Peter J., Tarassenko, Lionel, Clifton, David A.

“…Goal: Current methods for estimating respiratory rate (RR) from the photoplethysmogram (PPG) typically fail to distinguish between periods of high- and…”
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An assessment of algorithms to estimate respiratory rate from the electrocardiogram and photoplethysmogram by Charlton, Peter H, Bonnici, Timothy, Tarassenko, Lionel, Clifton, David A, Beale, Richard, Watkinson, Peter J

“…Over 100 algorithms have been proposed to estimate respiratory rate (RR) from the electrocardiogram (ECG) and photoplethysmogram (PPG). As they have never been…”
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Wearable Photoplethysmography for Cardiovascular Monitoring by Charlton, Peter H., Kyriacou, Panicos A., Mant, Jonathan, Marozas, Vaidotas, Chowienczyk, Phil, Alastruey, Jordi

“…Smart wearables provide an opportunity to monitor health in daily life and are emerging as potential tools for detecting cardiovascular disease (CVD)…”
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Signal-Quality Indices for the Electrocardiogram and Photoplethysmogram: Derivation and Applications to Wireless Monitoring by Orphanidou, Christina, Bonnici, Timothy, Charlton, Peter, Clifton, David, Vallance, David, Tarassenko, Lionel

“…The identification of invalid data in recordings obtained using wearable sensors is of particular importance since data obtained from mobile patients is, in…”
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Noninvasive hemodynamic indices of vascular aging: an in silico assessment by Hong, Jingyuan, Nandi, Manasi, Charlton, Peter H, Alastruey, Jordi

“…Vascular aging (VA) involves structural and functional changes in blood vessels that contribute to cardiovascular disease. Several noninvasive pulse wave (PW)…”
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Influence of Photoplethysmogram Signal Quality on Pulse Arrival Time during Polysomnography by Rinkevičius, Mantas, Charlton, Peter H, Bailón, Raquel, Marozas, Vaidotas

“…Intervals of low-quality photoplethysmogram (PPG) signals might lead to significant inaccuracies in estimation of pulse arrival time (PAT) during…”
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Breathing Rate Estimation From the Electrocardiogram and Photoplethysmogram: A Review by Charlton, Peter H., Birrenkott, Drew A., Bonnici, Timothy, Pimentel, Marco A. F., Johnson, Alistair E. W., Alastruey, Jordi, Tarassenko, Lionel, Watkinson, Peter J., Beale, Richard, Clifton, David A.

“…Breathing rate (BR) is a key physiological parameter used in a range of clinical settings. Despite its diagnostic and prognostic value, it is still widely…”
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A review of the effect of skin pigmentation on pulse oximeter accuracy by Al-Halawani, Raghda, Charlton, Peter H, Qassem, Meha, Kyriacou, Panayiotis A

“… Pulse oximetry is a non-invasive optical technique used to measure arterial oxygen saturation (SpO ) in a variety of clinical settings and scenarios. Despite…”
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Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR by Reaper, Philip M, Griffiths, Matthew R, Long, Joanna M, Charrier, Jean-Damien, MacCormick, Somhairle, Charlton, Peter A, Golec, Julian M C, Pollard, John R

“…A specific and potent inhibitor of the DNA damage response kinase ATR can exploit synthetic lethality between ATR and the related kinase ATM to sensitize…”
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Relationship between fiducial points on the peripheral and central blood pressure waveforms: rate of rise of the central waveform is a determinant of peripheral systolic blood pressure by Li, Ye, Guilcher, Antoine, Charlton, Peter H, Vennin, Samuel, Alastruey, Jordi, Chowienczyk, Phil

“…Central systolic blood pressure (cSBP, the peak of the central waveform) is usually regarded as the determinant of peripheral systolic blood pressure with…”
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Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities by Sanjiv, Kumar, Hagenkort, Anna, Calderón-Montaño, José Manuel, Koolmeister, Tobias, Reaper, Philip M., Mortusewicz, Oliver, Jacques, Sylvain A., Kuiper, Raoul V., Schultz, Niklas, Scobie, Martin, Charlton, Peter A., Pollard, John R., Berglund, Ulrika Warpman, Altun, Mikael, Helleday, Thomas

“…ATR and CHK1 maintain cancer cell survival under replication stress and inhibitors of both kinases are currently undergoing clinical trials. As ATR activity is…”
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Extraction of respiratory signals from the electrocardiogram and photoplethysmogram: technical and physiological determinants by Charlton, Peter H, Bonnici, Timothy, Tarassenko, Lionel, Alastruey, Jordi, Clifton, David A, Beale, Richard, Watkinson, Peter J

“…Breathing rate (BR) can be estimated by extracting respiratory signals from the electrocardiogram (ECG) or photoplethysmogram (PPG). The extracted respiratory…”
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Establishing best practices in photoplethysmography signal acquisition and processing by Charlton, Peter H, Pilt, Kristjan, Kyriacou, Panicos A

“…Photoplethysmography is now widely utilised by clinical devices such as pulse oximeters, and wearable devices such as smartwatches. It holds great promise for…”
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Inaccuracy of pulse oximetry with dark skin pigmentation: clinical implications and need for improvement by Kyriacou, Panicos A, Charlton, Peter H, Al-Halawani, Raghda, Shelley, Kirk H

“…Recent reports highlight potential inaccuracies of pulse oximetry in patients with various degrees of skin pigmentation. We summarise the literature, provide…”
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Energy-Efficient PPG-Based Respiratory Rate Estimation Using Spiking Neural Networks by Yang, Geunbo, Kang, Youngshin, Charlton, Peter H, Kyriacou, Panayiotis A, Kim, Ko Keun, Li, Ling, Park, Cheolsoo

“…Respiratory rate (RR) is a vital indicator for assessing the bodily functions and health status of patients. RR is a prominent parameter in the field of…”
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Detecting beats in the photoplethysmogram: benchmarking open-source algorithms by Charlton, Peter H, Kotzen, Kevin, Mejía-Mejía, Elisa, Aston, Philip J, Budidha, Karthik, Mant, Jonathan, Pettit, Callum, Behar, Joachim A, Kyriacou, Panicos A

“…The photoplethysmogram (PPG) signal is widely used in pulse oximeters and smartwatches. A fundamental step in analysing the PPG is the detection of heartbeats…”
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Assessing hemodynamics from the photoplethysmogram to gain insights into vascular age: a review from VascAgeNet by Charlton, Peter H, Paliakaitė, Birutė, Pilt, Kristjan, Bachler, Martin, Zanelli, Serena, Kulin, Dániel, Allen, John, Hallab, Magid, Bianchini, Elisabetta, Mayer, Christopher C, Terentes-Printzios, Dimitrios, Dittrich, Verena, Hametner, Bernhard, Veerasingam, Dave, Žikić, Dejan, Marozas, Vaidotas

“…The photoplethysmogram (PPG) signal is widely measured by clinical and consumer devices, and it is emerging as a potential tool for assessing vascular age. The…”
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Photoplethysmogram beat detection using Symmetric Projection Attractor Reconstruction by Pettit, Callum, Charlton, Peter H, Aston, Philip J

“…Many methods have been proposed to detect beats in photoplethysmogram (PPG) signals. We present a novel method which uses the Symmetric Projection Attractor…”
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The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy by Prevo, Remko, Fokas, Emmanouil, Reaper, Philip M., Charlton, Peter A., Pollard, John R., McKenna, W. Gillies, Muschel, Ruth J., Brunner, Thomas B.

“…DNA damaging agents such as radiotherapy and gemcitabine are frequently used for the treatment of pancreatic cancer. However, these treatments typically…”
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