Search Results - "Charlon, V"

The efficacy and safety of mibefradil in subgroups of patients with chronic stable angina pectoris by Charlon, V, Kobrin, I

“…The pool of controlled clinical studies on mibefradil, a new selective T-type calcium channel blocker, for the treatment of chronic stable angina pectoris was…”
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New developments in drug therapy of hypertension by Kobrin, I, Charlon, V, Bursztyn, M

“…The explosion of new knowledge about the complex mechanisms mediating high blood pressure is providing new targets for drug therapy of hypertension and other…”
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Effect of zinc deficiency on lipid peroxidation status and infarct size in rat hearts by Coudray, C, Charlon, V, de Leiris, J, Favier, A

“…The objective of this study was to investigate the effect of dietary zinc on endogenous production of lipid peroxides, and on myocardial infarct size in rats…”
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Hypertrophy induced alteration of action potential and effects of the inhibition of angiotensin converting enzyme by perindopril in infarcted rat hearts by Thollon, C, Kreher, P, Charlon, V, Rossi, A

“…Not much is known about alterations in electrical activity in the healthy part of a heart made hypertrophic as a result of local ischaemia, yet such an…”
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Adding the new calcium antagonist mibefradil to patients receiving long-term β-blocker therapy results in improved antianginal and antiischemic efficacy by Schneeweiss, Adam, Kobrin, Isaac, Charlon, Vincent, Caspi, Abraham, Marmor, Alon, Sclarovsky, Samuel, Reisin, Leonardo, Zchlesinger, Zvi

“…Objective The objective of this study was to evaluate the efficacy, tolerability, and safety of mibefradil, a new selective T-type calcium channel blocker, in…”
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The Effect of an Endothelin-Receptor Antagonist, Bosentan, on Blood Pressure in Patients with Essential Hypertension by Krum, Henry, Viskoper, Reuven J, Lacourciere, Yves, Budde, Michael, Charlon, Vincent

“…Endothelin-1 is a potent endothelium-derived vasoconstrictor peptide that has been implicated in the pathogenesis of hypertension and chronic heart failure. 1…”
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Clinical effects of endothelin receptor antagonism with bosentan in patients with severe chronic heart failure: results of a pilot study by Packer, Milton, McMurray, John, Massie, Barry M., Caspi, Abraham, Charlon, Vincent, Cohen-Solal, Alain, Kiowski, Wolfgang, Kostuk, William, Krum, Henry, Levine, Barry, Rizzon, Paolo, Soler, Jordi, Swedberg, Karl, Anderson, Susan, Demets, David L.

“…Endothelin receptor antagonism produces favorable short-term hemodynamic effects in heart failure, but the clinical effects of longer term therapy have not…”
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Reproducibility of angiotensin converting enzyme inhibitor induced cough: a double‐blind randomised study by Charlon, V, Dollow, S, Fidel, J, Hoglund, C, Honkanen, T, Kobrin, I, McEwan, J, McInnes, G, Viskoper, JR, Woo, KS, et al

“…1. The reproducibility of angiotensin converting enzyme inhibitor induced cough was examined in a double‐blind cross over study in patients previously shown to…”
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Ability of N-tert-butyl alpha phenylnitrone (PBN) to be used in isolated perfused heart spin trapping experiments: preliminary studies by CHARLON, V, DE LEIRIS, J

“…The aim of this study was to investigate the possibility of oxygen-free radical spin trapping with PBN, in models of isolated perfused hearts. Preliminary…”
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Eficiencia de uso del nitrógeno por forrajeras abonadas con estiércol de bovinos lecheros en la región pampeana, Argentina by Herrero, M.A, Charlón, Carbó, L.I, Cuatrín, Sardi, G.M.I, Romero

“…La intensificación de los sistemas ganaderos con el consiguiente aumento de la carga animal incrementa la cantidad de estiércol que puede ser reutilizado como…”
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Time dependency of the antihypertensive efficacy of the new renin inhibitor Ro 42-5892 by Viskoper, R J, Charlon, V, Laszt, A, Yosefy, C, Bock, J, Landau, M, Kobrin, I

“…The objective of this study was to assess the antihypertensive efficacy of the new renin inhibitor Ro 42-5892 in patients with essential hypertension treated…”
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Safety of Mibefradil, a New Once-a-Day, Selective T-Type Calcium Channel Antagonist by Kobrin, Isaac, Charlon, Vincent, Lindberg, Elisabeth, Pordy, Robert

“…The safety and tolerability of mibefradil, a selective T-type calcium channel antagonist, were evaluated in 3,430 patients with essential hypertension and…”
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Safety of mibefradil, a new once-a-day, selective T-type calcium channel antagonist: Pharmacologic and clinical perspectives on mibefradil: a new T-channel selective calcium antagonist by KOBRIN, I, CHARLON, V, LINDBERG, E, PORDY, R

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The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators by Krum, H, Viskoper, R J, Lacourciere, Y, Budde, M, Charlon, V

“…Endothelin is a powerful vasoconstrictor peptide derived from the endothelium. We evaluated the contribution of endothelin to blood-pressure regulation in…”
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Bosentan and the endothelin system in congestive heart failure by Ellahham, Samer H., Choucair, Wassim K., Charlon, Vincent, Abassi, Zaid, Calis, Karim A.

“…The endothelin system appears to play an important role in the pathophysiology of congestive heart failure (CHF). Endothelin receptor antagonists represent a…”
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Bosentan in Essential Hypertension by Haynes, W G, Ferro, C J, Webb, D J

“…To the Editor: Krum and colleagues (March 19 issue) 1 make the clinically important observation that the orally active endothelin ET A - and ET B -receptor…”
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Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist by Kobrin, I, Bieska, G, Charlon, V, Lindberg, E, Pordy, R

“…Mibefradil is the first of a new class of calcium antagonists (CAs), the tetralol derivatives, that selectively blocks the T-type calcium channel. The…”
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Effects of an orally active renin inhibitor, Ro 42-5892, in patients with essential hypertension by Kobrin, I, Viskoper, R J, Laszt, A, Bock, J, Weber, C, Charlon, V

“…Ro 42-5892 (Ro) is a new renin inhibitor that has been shown to be an orally effective compound in primates and in the first exploratory studies in humans…”
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Perspectives of in-situ measuring of oxygen free radicals by Charlon, V, de Leiris, J

“…It has been proposed that the oxygen free radicals (superoxide and hydroxyl radicals), could be partially responsible for the appearance of cellular…”
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Metabolic disorders generated by myocardial ischemia: implication of oxygen free radicals by de Leiris, J, Charlon, V

“…A process of myocardial ischemia is developed when there is an imbalance between the tissues needs and the supply in coronary arterial blood. This imbalance…”
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