Search Results - "Charlier, Michel"

High-LET Irradiation of a DNA-Binding Protein: Protein-Protein and DNA-Protein Crosslinks by Culard, Françoise, Bouffard, Serge, Charlier, Michel

“…Culard, F., Bouffard, S. and Charlier, M. High-LET Irradiation of a DNA-Binding Protein: Protein-Protein and DNA-Protein Crosslinks. Radiat. Res. 164, 774–780…”
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Direct Effect in DNA Radiolysis. Boron Neutron Capture Enhancement of Radiolysis in a Medical Fast-Neutron Beam by Sèche, Édouard, Sabattier, Roland, Bajard, Jean-Claude, Blondiaux, Gilbert, Breteau, Noël, Spotheim-Maurizot, Mélanie, Charlier, Michel

“…Sèche, E., Sabattier, R., Bajard, J-C., Blondiaux, G., Breteau, N., Spotheim-Maurizot, M. and Charlier, M. Direct Effect in DNA Radiolysis. Boron Neutron…”
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DNA Breakage upon K-Shell Excitation of Phosphorus as a Model for Direct Effects in Radiation Biology by Le Sech, Claude, Frohlich, Horst, Saint-Marc, Christelle, Charlier, Michel

“…Single-strand breaks (SSBs) and double-strand breaks (DSBs) induced in DNA under phosphorus K-shell resonant absorption have been studied using supercoiled…”
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Limitation of DNA-4',6-diamidine-2-phenylindole assay in the presence of an excess of tRNA by Katouzian-Safadi, M, Cremet, J Y, Charlier, M

“…4',6-Diamidino-2-phenylindole, DAPI, forms fluorescent complexes with DNA. This property has been used to quantify DNA on the basis of fluorometric test…”
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Response of a DNA-binding Protein to Radiation-induced Oxidative Stress by Culard, Françoise, Gervais, Alain, de Vuyst, Guillaume, Spotheim-Maurizot, Mélanie, Charlier, Michel

“…The DNA-binding protein MC1 is a chromosomal protein extracted from the archæbacterium Methanosarcina sp. CHTI55. It binds any DNA, and exhibits an enhanced…”
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Specific Recognition of Single-Stranded Regions in Ultraviolet-Irradiated and Heat-Denatured DNA by Tryptophan-Containing Peptides by Toulme, Jean-Jacques, Charlier, Michel, Helene, Claude

“…Fluorescence studies of the binding of peptides containing lysyl and tryptophyl residues to nucleic acids show that two types of complexes are formed. One of…”
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Radiolysis of lac repressor by (gamma)-rays and heavy ions: A two-hit model for protein inactivation by Charlier, Michel, Eon, Severine, Seche, Edouard, Bouffard, Serge

“…Upon gamma-ray or argon ion irradiation of the lac repressor protein, its peptide chain is cleaved and the protein loses its lac operator-binding activity, as…”
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Photosensitized splitting of pyrimidine dimers by indole derivatives and by tryptophan-containing oligopeptides and proteins by Hélène, C, Charlier, M

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Radiation Abolishes Inducer Binding to Lactose Repressor by Gillard, Nathalie, Spotheim-Maurizot, Mélanie, Charlier, Michel

“…Gillard, N., Spotheim-Maurizot, M. and Charlier, M. Radiation Abolishes Inducer Binding to Lactose Repressor. Radiat. Res. 163, 433–446 (2005). The lactose…”
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Radiation Disrupts Protein–DNA Complexes through Damage to the Protein. The lac Repressor–Operator System by Eon, Séverine, Culard, Françoise, Sy, Denise, Charlier, Michel, Spotheim-Maurizot, Mélanie

“…Eon, S., Culard, F., Sy, D., Charlier, M. and Spotheim-Maurizot, M. Radiation Disrupts Protein–DNA Complexes through Damage to the Protein. The lac…”
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RADACK, a Stochastic Simulation of Hydroxyl Radical Attack to DNA by Begusova, Marie, Spotheim-Maurizot, Mélanie, Sy, Denise, Michalik, Veslav, Charlier, Michel

“…RADACK was conceived to simulate the radiation-induced attack to different DNA forms and complexes. It allows to separately calculate the probability of attack…”
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Radiolysis of lac Repressor by γ-Rays and Heavy Ions: A Two-Hit Model for Protein Inactivation by Charlier, Michel, Eon, Séverine, Sèche, Édouard, Bouffard, Serge, Culard, Françoise, Spotheim-Maurizot, Mélanie

“…Upon γ-ray or argon ion irradiation of the lac repressor protein, its peptide chain is cleaved and the protein loses its lac operator-binding activity, as…”
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Radiolysis of DNA–protein complexes by Běgusová, Marie, Gillard, Nathalie, Sy, Denise, Castaing, Bertrand, Charlier, Michel, Spotheim-Maurizot, Melanie

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Radiation Disrupts Protein: DNA Complexes through Damage to the Protein. The Iac Repressor: Operator System by Eon, Séverine, Culard, Françoise, Sy, Denise, Charlier, Michel, Spotheim-Maurizot, Mélanie

“…Binding of a protein to its cognate DNA sequence is a key step in the regulation of gene expression. If radiation damage interferes with protein-DNA…”
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Consequences of intramolecular dityrosine formation on a DNA–protein complex: a molecular modeling study by Gras, Julien, Sy, Denise, Eon, Séverine, Charlier, Michel, Spotheim-Maurizot, Melanie

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Radiolytic footprinting. .beta. Rays, .gamma. photons, and fast neutrons probe DNA-protein interactions by Franchet-Beuzit, Jenny, Spotheim-Maurizot, Melanie, Sabattier, Roland, Blazy-Baudras, Bernadette, Charlier, Michel

“…Ionizing radiations induce numerous damages in DNA, especially strand breaks. The hydroxyl radical OH., produced by the radiolysis of water, is mainly…”
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Radiolytic signature of Z-DNA by Tartier, Laurence, Michalik, Veslav, Spotheim-Maurizot, Melanie, Rahmouni, A.Rachid, Sabattier, Roland, Charlier, Michel

“…Ionizing radiations induce various damages in DNA via the hydroxyl radical OH generated by the radlolysis of water. We compare here the radlosensltlvlty of B-…”
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Base-specific Photocleavage of DNA Induced by Pazelliptine Sensitization: Study of the Mechanism by Time-resolved Absorption and Fluorescence by Fontaine-Aupart, Marie-Pierre, Renault, Eric, Videlot, Christine, Tfibel, Francis, Pansu, Robert, Charlier, Michel, Pernot, Pascal

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Base-specific Photocleavage of DNA Induced by Pazelliptine Sensitization: Study of the Mechanism by Time-resolved Absorption and Fluorescence by Fontaine-Aupart, Marie-Pierre, Renault, Eric, Videlot, Christine, Tfibel, Francis, Pansu, Robert, Charlier, Michel, Pernot, Pascal

“…The intercalating antitumoral drug pazelliptine (PZE) is able to photosensitize the formation of single‐ and double‐strand breaks in supercoiled plasmid DNA…”
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DNA radiolysis. Mapping of the gene regulation domains by Spotheim-Maurizot, Mélanie, Franchet-Beuzit, Jenny, Isabelle, Valerie, Tartier, Laurence, Charlier, Michel

“…Ionizing radiations induce strand breaks and modifications of nucleotides (base and/or sugar) in DNA. In aerated solution, the damages are mainly due to the…”
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