Search Results - "Charlesworth, Jonathan D."

Adjunctive tonic motor activation enables opioid reduction for refractory restless legs syndrome: a prospective, open-label, single-arm clinical trial by Buchfuhrer, Mark J, Roy, Asim, Rodriguez, Stephanye, Charlesworth, Jonathan D

“…There is a large population of restless legs syndrome (RLS) patients who are refractory to medication. Whereas experts recommend off-label opioids as an…”
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Mechanisms and time course of vocal learning and consolidation in the adult songbird by Warren, Timothy L, Tumer, Evren C, Charlesworth, Jonathan D, Brainard, Michael S

“…In songbirds, the basal ganglia outflow nucleus LMAN is a cortical analog that is required for several forms of song plasticity and learning. Moreover, in…”
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Lesions in a songbird vocal circuit increase variability in song syntax by Koparkar, Avani, Warren, Timothy L, Charlesworth, Jonathan D, Shin, Sooyoon, Brainard, Michael S, Veit, Lena

“…Complex skills like speech and dance are composed of ordered sequences of simpler elements, but the neuronal basis for the syntactic ordering of actions is…”
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Learning the microstructure of successful behavior by Charlesworth, Jonathan D, Tumer, Evren C, Warren, Timothy L, Brainard, Michael S

“…Reinforcement signals indicating success or failure are known to alter the probability of selecting between distinct actions. Here the authors examine the…”
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Variable sequencing is actively maintained in a well learned motor skill by Warren, Timothy L, Charlesworth, Jonathan D, Tumer, Evren C, Brainard, Michael S

“…Variation in sequencing of actions occurs in many natural behaviors, yet how such variation is maintained is poorly understood. We investigated maintenance of…”
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Bilateral high-frequency noninvasive peroneal nerve stimulation evokes tonic leg muscle activation for sleep-compatible reduction of restless legs syndrome symptoms by Charlesworth, Jonathan D, Adlou, Bahman, Singh, Haramandeep, Buchfuhrer, Mark J

“…Restless legs syndrome (RLS) is a prevalent sleep disorder with limited treatment options. Bilateral high-frequency noninvasive peroneal nerve stimulation…”
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Long-term efficacy and safety of tonic motor activation for treatment of medication-refractory restless legs syndrome: A 24-Week Open-Label Extension Study by Roy, Asim, Ojile, Joseph, Kram, Jerrold, Olin, Jonathan, Rosenberg, Russell, Hudson, J Douglas, Bogan, Richard K, Charlesworth, Jonathan D

“…Abstract Study Objectives To evaluate long-term efficacy and safety of tonic motor activation (TOMAC) for treatment of medication-refractory moderate-to-severe…”
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Efficacy and safety of TOMAC for treatment of medication-naïve and medication-refractory restless legs syndrome: A randomized clinical trial and meta-analysis by Singh, Haramandeep, Baker, Fiona C., Ojile, Joseph, Adlou, Bahman, Kolotovska, Viktoriia, Rigot, Stephanie K., Charlesworth, Jonathan D.

“…There is a significant unmet need for safe and effective nonpharmacological therapies for restless legs syndrome (RLS). The objective was to evaluate the…”
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Efficacy and safety of tonic motor activation (TOMAC) for medication-refractory restless legs syndrome: a randomized clinical trial by Bogan, Richard K, Roy, Asim, Kram, Jerrold, Ojile, Joseph, Rosenberg, Russell, Hudson, J Douglas, Scheuller, H Samuel, Winkelman, John W, Charlesworth, Jonathan D

“…Abstract Study Objectives The purpose of this study was to evaluate the efficacy and safety/tolerability of bilateral high-frequency tonic motor activation…”
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Noninvasive neuromodulation reduces symptoms of restless legs syndrome by Buchfuhrer, Mark J, Baker, Fiona C, Singh, Haramandeep, Kolotovska, Viktoriia, Adlou, Bahman, Anand, Harnadar, de Zambotti, Massimiliano, Ismail, Mehvish, Raghunathan, Shriram, Charlesworth, Jonathan D

“…Restless legs syndrome (RLS) is a common neurological disorder characterized by an uncontrollable nocturnal urge to move the legs and often associated with…”
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Transdermal neuromodulation of noradrenergic activity suppresses psychophysiological and biochemical stress responses in humans by Tyler, William J., Boasso, Alyssa M., Mortimore, Hailey M., Silva, Rhonda S., Charlesworth, Jonathan D., Marlin, Michelle A., Aebersold, Kirsten, Aven, Linh, Wetmore, Daniel Z., Pal, Sumon K.

“…We engineered a transdermal neuromodulation approach that targets peripheral (cranial and spinal) nerves and utilizes their afferent pathways as signaling…”
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Covert skill learning in a cortical-basal ganglia circuit by Charlesworth, Jonathan D., Warren, Timothy L., Brainard, Michael S.

“…In Bengalese finches, a basal ganglia circuit, the anterior forebrain pathway, can covertly acquire the ability to adaptively modify song without contributing…”
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Decreased sensitivity in adolescent vs. adult rats to the locomotor activating effects of toluene by Bowen, Scott E, Charlesworth, Jonathan D, Tokarz, Mary E, Wright, M. Jerry, Wiley, Jenny L

“…Abstract Volatile organic solvent (inhalant) abuse continues to be a major health concern throughout the world. Of particular concern is the abuse of inhalants…”
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Lesions in a songbird vocal circuit increase variability in song syntax by Koparkar, Avani, Warren, Timothy L, Charlesworth, Jonathan D, Shin, Sooyoon, Brainard, Michael S, Veit, Lena

“…Complex skills like speech and dance are composed of ordered sequences of simpler elements, but the neuronal basis for the syntactic ordering of actions is…”
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Principles of trial-and-error leaming in adult birdsong by Charlesworth, Jonathan D

“…Trial-and-error skill learning involves generating variation in behavioral performance ('exploratory variation') and modifying the motor program to produce the…”
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Decreased Sensitivity in Adolescent versus Adult Rats to the Locomotor Activating Effects of Toluene by Bowen, Scott E., Charlesworth, Jonathan D., Tokarz, Mary E., Jerry Wright, M., Wiley, Jenny L.

“…Volatile organic solvent (inhalant) abuse continues to be a major health concern throughout the world. Of particular concern is the abuse of inhalants by…”
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