Search Results - "Charlesworth, G"

A comprehensive survey of C. elegans argonaute proteins reveals organism-wide gene regulatory networks and functions by Seroussi, Uri, Lugowski, Andrew, Wadi, Lina, Lao, Robert X, Willis, Alexandra R, Zhao, Winnie, Sundby, Adam E, Charlesworth, Amanda G, Reinke, Aaron W, Claycomb, Julie M

“…Argonaute (AGO) proteins associate with small RNAs to direct their effector function on complementary transcripts. The nematode contains an expanded family of…”
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Selling surveillance technology: semiotic themes in advertisements for ageing in place with dementia by Vermeer, Y., Higgs, P., Charlesworth, G.

“…Six advertisements were explored that sell surveillance technologies for people living with dementia through qualitative content analysis. Advertisements from…”
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Continuous intravenous anakinra for treating severe secondary haemophagocytic lymphohistiocytosis/macrophage activation syndrome in critically ill children by Charlesworth, James E.G., Wilson, Shaun, Qureshi, Amrana, Blanco, Esther, Mitchell, Amy, Segal, Shelley, Kelly, Dominic, Weitz, James, O'Shea, Deirdre, Bailey, Kathryn, Kavirayani, Akhila

“…The cytokine storm of secondary haemophagocytic lymphohistiocytosis (sHLH)/macrophage activation syndrome (MAS) can cause life‐threatening multiorgan failure…”
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Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility by Charlesworth, Amanda G, Seroussi, Uri, Lehrbach, Nicolas J, Renaud, Mathias S, Sundby, Adam E, Molnar, Ruxandra I, Lao, Robert X, Willis, Alexandra R, Woock, Jenna R, Aber, Matthew J, Diao, Annette J, Reinke, Aaron W, Ruvkun, Gary, Claycomb, Julie M

“…Abstract The Caenorhabditis elegans genome encodes nineteen functional Argonaute proteins that use 22G-RNAs, 26G-RNAs, miRNAs or piRNAs to regulate target…”
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Double lesion MRgFUS thalamotomy for essential tremor: 4.5-year outcomes and framework for assessing loss of efficacy and tremor progression by van der Stouwe, A M M, Jameel, A, Gedroyc, W, Jones, B, Charlesworth, G, Molloy, S, Tai, Y, Nandi, D, Bain, P G

“…The essential tremor (ET) course to 54 months post-unilateral VIM/PSA magnetic resonance-guided focused ultrasound (MRgFUS) in the treated arm (TA) and…”
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Mitochondrial complex I NUBPL mutations cause combined dystonia with bilateral striatal necrosis and cerebellar atrophy by Balint, B., Charlesworth, G., Stamelou, M., Carr, L., Mencacci, N. E., Wood, N. W., Bhatia, K. P.

“…Background and purpose The recent advances in genetics have helped to unravel the cause of many dystonia syndromes. With the broadening spectrum of genetically…”
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Toward Analysis at the Point of Need: A Digital Microfluidic Approach to Processing Multi‐Source Sexual Assault Samples by Elsayed, Mohamed, Bodo, Leticia, Gaoiran, Christine, Keuhnelian, Palig, Dosajh, Advikaa, Luk, Vivienne, Schwandt, Melissa, French, Julie L., Ghosh, Alpana, Erickson, Barbara, Charlesworth, Amanda G., Millman, Jonathan, Wheeler, Aaron R.

“…Forensic case samples collected in sexual assaults typically contain DNA from multiple sources, which complicates short‐tandem repeat (STR) profiling. These…”
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Equations defined using gene expression and histological data resolve coeliac disease biopsies within the Marsh score continuum by Charlesworth, Richard P.G., Agnew, Linda L., Scott, David R., Andronicos, Nicholas M.

“…The gold standard diagnostic for coeliac disease (CD) is subjective histological assignment of biopsies into the Marsh score categories. It is hypothesized…”
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Does befriending by trained lay workers improve psychological well-being and quality of life for carers of people with dementia, and at what cost? A randomised controlled trial by Charlesworth, G, Shepstone, L, Wilson, E, Thalanany, M, Mugford, M, Poland, F

“…OBJECTIVESTo determine whether a social support intervention (access to an employed befriending facilitator in addition to usual care) is effective compared…”
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The geology of the Matala Dome: an important piece of the Pan-African puzzle in Central Zambia by Naydenov, K. V., Lehmann, J., Saalmann, K., Milani, L., Poterai, J., Kinnaird, J. A., Charlesworth, G., Kramers, J. D.

“…The Matala Dome (MD), an ENE-trending structure located at the junction between the Pan-African Lufilian and Zambezi belts, is cored by a Gneiss-Schist Unit…”
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Tremulous cervical dystonia is likely to be familial: Clinical characteristics of a large cohort by Rubio-Agusti, I, Pareés, I, Kojovic, M, Stamelou, M, Saifee, T.A, Charlesworth, G, Sheerin, U.M, Edwards, M.J, Bhatia, K.P

“…Abstract Background Primary cervical dystonia is the most common form of adult-onset focal dystonia. Although most frequently sporadic, 15–20% of patients…”
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661 Identifying children ‘missing’ during UK COVID-19 lockdown: A retrospective cohort study (2015–2020) of Oxfordshire ED attendances and inpatient diagnoses by Charlesworth, James EG, Bold, Rhian, Pal, Rani

“…BackgroundOn 23rd March 2020, the UK ‘stay at home’ order heralded the first national lockdown, lasting 7-weeks. Dramatic reductions of paediatric…”
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P Granules Protect RNA Interference Genes from Silencing by piRNAs by Ouyang, John Paul T., Folkmann, Andrew, Bernard, Lauren, Lee, Chih-Yung, Seroussi, Uri, Charlesworth, Amanda G., Claycomb, Julie M., Seydoux, Geraldine

“…P granules are perinuclear condensates in C. elegans germ cells proposed to serve as hubs for self/non-self RNA discrimination by Argonautes. We report that a…”
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1252 Neonatal SARS-CoV-2 antibodies at day 14 of life, 3.5-fold higher than her COVID-19 asymptomatic mother by Charlesworth, James EG, Bhatt, Ree’Thee, Kapila, Poonam, Misra, Indranil

“…BackgroundThroughout the COVID-19 pandemic, it has been unclear how SARS-CoV-2 infection (by vertical transmission or natural infection) would affect neonates,…”
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PIWI puts spermatogenesis in its place by Charlesworth, Amanda G, Nitschko, Volker, Renaud, Mathias S, Claycomb, Julie M

“…In this issue of Developmental Cell, Cornes et al. show that piRNAs initiate transcriptional silencing of spermatogenesis genes in the C. elegans germline via…”
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Next-Gen Learning: The C. elegans Approach by Charlesworth, Amanda G., Seroussi, Uri, Claycomb, Julie M.

“…In this issue, Moore et al. and Posner et al., provide evidence for how the activity of the nervous system in C. elegans results in gene expression changes in…”
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A Flexible Strategy for the Regiocontrolled Synthesis of Pyrazolo­[1,5‑a]­pyrazines by Lindsay-Scott, Peter J, Charlesworth, Natalie G, Grozavu, Alexandru

“…A four-step protocol for the synthesis of pyrazolo­[1,5-a]­pyrazines has been developed. Commercially available pyrazoles were alkylated and formylated in a…”
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Mental health of carers by Charlesworth, G. M.

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Carers Assessment of Difficulties Index (CADI): Psychometric properties for use with carers of people with dementia by Charlesworth, G. M., Tzimoula, X. M., Newman, S. P.

“…Burden is a commonly recognised phenomenon in family caring. The Carers Assessment of Difficulties Index (CADI) was developed as a clinical tool for assessing…”
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Mind the (preterm) gap: inequality in the UK’s current RSV immunisation approach will leave many preterm babies unprotected against RSV this winter by Charlesworth, James E G

“…Both products were found to offer favourable RSV prophylaxis, leading to the Department of Health and Social Care tendering the infant RSV prophylactic…”
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