Search Results - "Charlesworth, Cristine M."

Exostosin 1/Exostosin 2-Associated Membranous Nephropathy by Sethi, Sanjeev, Madden, Benjamin J, Debiec, Hanna, Charlesworth, M Cristine, Gross, LouAnn, Ravindran, Aishwarya, Hummel, Amber M, Specks, Ulrich, Fervenza, Fernando C, Ronco, Pierre

“…In membranous nephropathy (MN), which is characterized by deposition of immune complexes along the glomerular basement membrane (GBM), phospholipase A2…”
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Neural epidermal growth factor-like 1 protein (NELL-1) associated membranous nephropathy by Sethi, Sanjeev, Debiec, Hanna, Madden, Benjamin, Charlesworth, M Cristine, Morelle, Johann, Gross, LouAnn, Ravindran, Aishwarya, Buob, David, Jadoul, Michel, Fervenza, Fernando C, Ronco, Pierre

“…Membranous nephropathy is characterized by deposition of immune complexes along the glomerular basement membrane. PLA2R and THSD7A are target antigens in 70%…”
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Semaphorin 3B-associated membranous nephropathy is a distinct type of disease predominantly present in pediatric patients by Sethi, Sanjeev, Debiec, Hanna, Madden, Benjamin, Vivarelli, Marina, Charlesworth, M Cristine, Ravindran, Aishwarya, Gross, LouAnn, Ulinski, Tim, Buob, David, Tran, Cheryl L, Emma, Francesco, Diomedi-Camassei, Francesca, Fervenza, Fernando C, Ronco, Pierre

“…Membranous nephropathy results from subepithelial antigen-antibody complex deposition along the glomerular basement membrane. Although PLA2R, THSD7A, and…”
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In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes by Ravindran, Aishwarya, Casal Moura, Marta, Fervenza, Fernando C, Nasr, Samih H, Alexander, Mariam P, Fidler, Mary E, Herrera Hernandez, Loren P, Zhang, Pingchuan, Grande, Joseph P, Cornell, Lynn D, Gross, Lou Ann, Negron, Vivian, Jenson, Grace E, Madden, Benjamin J, Charlesworth, M Cristine, Sethi, Sanjeev

“…In patients with secondary (autoimmune) membranous nephropathy, two novel proteins, Exostosin 1 and Exostosin 2 (EXT1/EXT2), are potential disease antigens,…”
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Proteomic Analysis of Exosomes and Exosome‐Free Conditioned Media From Human Osteosarcoma Cell Lines Reveals Secretion of Proteins Related to Tumor Progression by Jerez, Sofía, Araya, Héctor, Thaler, Roman, Charlesworth, M. Cristine, López‐Solís, Remigio, Kalergis, Alexis M., Céspedes, Pablo F., Dudakovic, Amel, Stein, Gary S., van Wijnen, Andre J., Galindo, Mario

“…ABSTRACT Osteosarcomas are the most prevalent bone tumors in pediatric patients, but can also occur later in life. Bone tumors have the potential to…”
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Subfractionation, characterization, and in-depth proteomic analysis of glomerular membrane vesicles in human urine by Hogan, Marie C, Johnson, Kenneth L, Zenka, Roman M, Charlesworth, M Cristine, Madden, Benjamin J, Mahoney, Doug W, Oberg, Ann L, Huang, Bing Q, Leontovich, Alexey A, Nesbitt, Lisa L, Bakeberg, Jason L, McCormick, Daniel J, Bergen, H Robert, Ward, Christopher J

“…Urinary exosome-like vesicles (ELVs) are a heterogenous mixture (diameter 40-200 nm) containing vesicles shed from all segments of the nephron including…”
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Characterization of PKD Protein-Positive Exosome-Like Vesicles by HOGAN, Marie C, MANGANELLI, Luca, CRISTINE CHARLESWORTH, M, TORRES, Vicente E, LARUSSO, Nicholas F, HARRIS, Peter C, WARD, Christopher J, WOOLLARD, John R, MASYUK, Anatoliy I, MASYUK, Tatyana V, TAMMACHOTE, Rachaneekorn, HUANG, Bing Q, LEONTOVICH, Alexey A, BEITO, Thomas G, MADDEN, Benjamin J

“…Proteins associated with autosomal dominant and autosomal recessive polycystic kidney disease (polycystin-1, polycystin-2, and fibrocystin) localize to various…”
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ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance by Orme, Jacob J., Jazieh, Khalid A., Xie, Tiancheng, Harrington, Susan, Liu, Xin, Ball, Matthew, Madden, Benjamin, Charlesworth, M. Cristine, Azam, Tariq U., Lucien, Fabrice, Wootla, Bharath, Li, Yanli, Villasboas, Jose Caetano, Mansfield, Aaron S., Dronca, Roxana S., Dong, Haidong

“…ADAM10 and ADAM17 expression and soluble PD-L1 (sPD-L1) predict poor prognosis in many malignancies, including in patients treated with PD-(L)1 inhibitors. The…”
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Identification of Biomarkers for PKD1 Using Urinary Exosomes by Hogan, Marie C, Bakeberg, Jason L, Gainullin, Vladimir G, Irazabal, Maria V, Harmon, Amber J, Lieske, John C, Charlesworth, M Cristine, Johnson, Kenneth L, Madden, Benjamin J, Zenka, Roman M, McCormick, Daniel J, Sundsbak, Jamie L, Heyer, Christina M, Torres, Vicente E, Harris, Peter C, Ward, Christopher J

“…Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of ESRD. Affected individuals inherit a defective copy of either PKD1 or PKD2, which…”
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Analysis of the polycystin complex (PCC) in human urinary exosome–like vesicles (ELVs) by Lea, Wendy A., McGreal, Kerri, Sharma, Madhulika, Parnell, Stephen C., Zelenchuk, Lesya, Charlesworth, M. Cristine, Madden, Benjamin J., Johnson, Kenneth L., McCormick, Daniel J., Hogan, Marie C., Ward, Christopher J.

“…The polycystin–1 (PC1), polycystin–2 (PC2) and fibrocystin proteins, the respective products of the PKD1 , PKD2 and PKHD1 genes, are abundant in urinary…”
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Writers and readers of H3K9me2 form distinct protein networks during the cell cycle that include candidates for H3K9 mimicry by Pollin, Gareth, De Assuncao, Thiago M, Doria Jorge, Salomao, Chi, Young-In, Charlesworth, M Cristine, Madden, Benjamin, Iovanna, Juan, Zimmermann, Michael T, Urrutia, Raul, Lomberk, Gwen

“…Histone H3 lysine 9 methylation (H3K9me), which is written by the Euchromatic Histone Lysine Methyltransferases EHMT1 and EHMT2 and read by the heterochromatin…”
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Proteome study of cutaneous lupus erythematosus (CLE) and dermatomyositis skin lesions reveals IL-16 is differentially upregulated in CLE by Niewold, Timothy B, Meves, Alexander, Lehman, Julia S, Popovic-Silwerfeldt, Karin, Häyry, Aliisa, Söderlund-Matell, Therese, Charlesworth, Cristine M, Madden, Benjamin, Lundberg, Ingrid E, Wahren-Herlenius, Marie, Svenungsson, Elisabet, Oke, Vilija

“…The objective of the study was to explore the disease pathways activated in the inflammatory foci of skin lesions in cutaneous lupus erythematosus (CLE) and…”
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Proteomic Analysis of Complement Proteins in Membranous Nephropathy by Ravindran, Aishwarya, Madden, Benjamin, Charlesworth, M. Cristine, Sharma, Rishi, Sethi, Amit, Debiec, Hanna, Cattran, Daniel, Fervenza, Fernando C., Smith, Richard J., Ronco, Pierre, Sethi, Sanjeev

“…Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in Caucasian adults. Phospholipase A2 receptor (PLA2R)– and exostosin 1…”
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Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology by Qiao, Wenhui, Chen, Yixing, Zhong, Jun, Madden, Benjamin J, Charlesworth, Cristine M, Martens, Yuka A, Liu, Chia-Chen, Knight, Joshua, Ikezu, Tadafumi C, Kurti, Aishe, Zhu, Yiyang, Meneses, Axel, Rosenberg, Cassandra L, Kuchenbecker, Lindsey A, Vanmaele, Lucy K, Li, Fuyao, Chen, Kai, Shue, Francis, Dacquel, Maxwell V, Fryer, John, Pandey, Akhilesh, Zhao, Na, Bu, Guojun

“…The rare p.H157Y variant of TREM2 (Triggering Receptor Expressed on Myeloid Cells 2) was found to increase Alzheimer's disease (AD) risk. This mutation is…”
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Molecular signatures of inherited and acquired sporadic late onset nemaline myopathies by Nicolau, Stefan, Dasgupta, Aneesha, Dasari, Surendra, Charlesworth, M Cristine, Johnson, Kenneth L, Pandey, Akhilesh, Doles, Jason D, Milone, Margherita

“…Acquired sporadic late onset nemaline myopathy (SLONM) and inherited nemaline myopathy (iNM) both feature accumulation of nemaline rods in muscle fibers…”
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Surfaceome Profiling of Rhabdomyosarcoma Reveals B7-H3 as a Mediator of Immune Evasion by Lavoie, Roxane R., Gargollo, Patricio C., Ahmed, Mohamed E., Kim, Yohan, Baer, Emily, Phelps, Doris A., Charlesworth, Cristine M., Madden, Benjamin J., Wang, Liguo, Houghton, Peter J., Cheville, John, Dong, Haidong, Granberg, Candace F., Lucien, Fabrice

“…Novel therapeutic strategies are needed for the treatment of rhabdomyosarcoma (RMS), the most common soft-tissue sarcoma in children. By using a combination of…”
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Correction: Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology by Qiao, Wenhui, Chen, Yixing, Zhong, Jun, Madden, Benjamin J, Charlesworth, Cristine M, Martens, Yuka A, Liu, Chia-Chen, Knight, Joshua, Ikezu, Tadafumi C, Kurti, Aishe, Zhu, Yiyang, Meneses, Axel, Rosenberg, Cassandra L, Kuchenbecker, Lindsey A, Vanmaele, Lucy K, Li, Fuyao, Chen, Kai, Shue, Francis, Dacquel, Maxwell V, Fryer, John, Pandey, Akhilesh, Zhao, Na, Bu, Guojun

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An atlas of the bone marrow bone proteome in patients with dysproteinemias by Ho, Matthew, Dasari, Surendra, Visram, Alissa, Drake, Matthew T., Charlesworth, M. Cristine, Johnson, Kenneth L., Pujari, Ganesh P., Jevremovic, Dragan, Kourelis, Taxiarchis

“…Multiple myeloma (MM) bone disease is a significant cause of morbidity but there is a paucity of data on the impact of malignant plasma cells on adjacent…”
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The proteome of distal nerves: implication in delayed repair and poor functional recovery by Guo, Song, Moore, Raymond, Charlesworth, M, Johnson, Kenneth, Spinner, Robert, Windebank, Anthony, Wang, Huan

“…Chronic denervation is one of the key factors that affect nerve regeneration. Chronic axotomy deteriorates the distal nerve stump, causes protein changes, and…”
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Recognition of Fungal Protease Activities Induces Cellular Activation and Eosinophil-Derived Neurotoxin Release in Human Eosinophils by Matsuwaki, Yoshinori, Wada, Kota, White, Thomas A, Benson, Linda M, Charlesworth, M. Cristine, Checkel, James L, Inoue, Yoshinari, Hotta, Kyoko, Ponikau, Jens U, Lawrence, Christopher B, Kita, Hirohito

“…Eosinophils are multifunctional leukocytes implicated in the pathogenesis of asthma and in immunity to certain organisms. Associations between exposure to an…”
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