Search Results - "Charleston, Bryan"

Using cross-species vaccination approaches to counter emerging infectious diseases by Warimwe, George M., Francis, Michael J., Bowden, Thomas A., Thumbi, Samuel M., Charleston, Bryan

“…Since the initial use of vaccination in the eighteenth century, our understanding of human and animal immunology has greatly advanced and a wide range of…”
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Foot-and-mouth disease virus localisation on follicular dendritic cells and sustained induction of neutralising antibodies is dependent on binding to complement receptors (CR2/CR1) by Gordon, Lucy, Mabbott, Neil, Wells, Joanna, Kulik, Liudmila, Juleff, Nick, Charleston, Bryan, Perez-Martin, Eva

“…Previous studies have shown after the resolution of acute infection and viraemia, foot-and-mouth disease virus (FMDV) capsid proteins and/or genome are…”
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Options for control of foot-and-mouth disease: knowledge, capability and policy by Paton, David J., Sumption, Keith J., Charleston, Bryan

“…Foot-and-mouth disease can be controlled by zoo-sanitary measures and vaccination but this is difficult owing to the existence of multiple serotypes of the…”
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Type I and III interferon production in response to RNA viruses by Reid, Elizabeth, Charleston, Bryan

“…The biology of RNA viruses is closely linked to the type I and type III interferon (IFN) response of the host. These viruses display a range of molecular…”
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Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus by Kotecha, Abhay, Wang, Quan, Dong, Xianchi, Ilca, Serban L., Ondiviela, Marina, Zihe, Rao, Seago, Julian, Charleston, Bryan, Fry, Elizabeth E., Abrescia, Nicola G. A., Springer, Timothy A., Huiskonen, Juha T., Stuart, David I.

“…Foot-and-mouth disease virus (FMDV) mediates cell entry by attachment to an integrin receptor, generally αvβ6, via a conserved arginine–glycine–aspartic acid…”
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Comparison of Heterosubtypic Protection in Ferrets and Pigs Induced by a Single-Cycle Influenza Vaccine by Holzer, Barbara, Morgan, Sophie B, Matsuoka, Yumi, Edmans, Matthew, Salguero, Francisco J, Everett, Helen, Brookes, Sharon M, Porter, Emily, MacLoughlin, Ronan, Charleston, Bryan, Subbarao, Kanta, Townsend, Alain, Tchilian, Elma

“…Influenza is a major health threat, and a broadly protective influenza vaccine would be a significant advance. Signal Minus FLU (S-FLU) is a candidate broadly…”
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Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen by Porta, Claudine, Kotecha, Abhay, Burman, Alison, Jackson, Terry, Ren, Jingshan, Loureiro, Silvia, Jones, Ian M, Fry, Elizabeth E, Stuart, David I, Charleston, Bryan

“…Foot-and-mouth disease remains a major plague of livestock and outbreaks are often economically catastrophic. Current inactivated virus vaccines require…”
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Timelines of infection and transmission dynamics of H1N1pdm09 in swine by Canini, Laetitia, Holzer, Barbara, Morgan, Sophie, Dinie Hemmink, Johanneke, Clark, Becky, Woolhouse, Mark E J, Tchilian, Elma, Charleston, Bryan

“…Influenza is a major cause of mortality and morbidity worldwide. Despite numerous studies of the pathogenesis of influenza in humans and animal models the…”
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Generation and Characterisation of Monoclonal Antibodies against Nairobi Sheep Disease Virus Nucleoprotein by Maze, Emmanuel A, Chrun, Tiphany, Booth, George, Limon, Georgina, Charleston, Bryan, Lambe, Teresa

“…Nairobi sheep disease (NSD), caused by the viral agent NSD virus (NSDV), is a haemorrhagic fever disease affecting and inducing high mortality in sheep and…”
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Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the foot-and-mouth disease virus capsid by Ferretti, Luca, Pérez-Martín, Eva, Zhang, Fuquan, Maree, François, de Klerk-Lorist, Lin-Mari, van Schalkwykc, Louis, Juleff, Nicholas D, Charleston, Bryan, Ribeca, Paolo

“…Although recombination is known to occur in foot-and-mouth disease virus (FMDV), it is considered only a minor determinant of virus sequence diversity…”
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Relationship Between Clinical Signs and Transmission of an Infectious Disease and the Implications for Control by Charleston, Bryan, Bankowski, Bartlomies M., Gubbins, Simon, Chase-Topping, Margo E., Schley, David, Howey, Richard, Barnett, Paul V., Gibson, Debi, Juleff, Nicholas D., Woolhouse, Mark E. J.

“…Control of many infectious diseases relies on the detection of clinical cases and the isolation, removal, or treatment of cases and their contacts. The success…”
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Application of the thermofluor PaSTRy technique for improving foot-and-mouth disease virus vaccine formulation by Kotecha, Abhay, Zhang, Fuquan, Juleff, Nicholas, Jackson, Terry, Perez, Eva, Stuart, Dave, Fry, Elizabeth, Charleston, Bryan, Seago, Julian

“…Foot-and-mouth disease (FMD) has a major economic impact throughout the world and is a considerable threat to food security. Current FMD virus (FMDV) vaccines…”
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Viral dynamics and immune responses to foot-and-mouth disease virus in African buffalo (Syncerus caffer) by Perez-Martin, Eva, Beechler, Brianna, Zhang, Fuquan, Scott, Katherine, de Klerk-Lorist, Lin-Mari, Limon, Georgina, Dugovich, Brian, Gubbins, Simon, Botha, Arista, Hetem, Robyn, van Schalkwyk, Louis, Juleff, Nicholas, Maree, Francois F., Jolles, Anna, Charleston, Bryan

“…Abstract Foot-and-mouth disease (FMD) is one of the most important livestock diseases restricting international trade. While African buffalo ( Syncerus caffer…”
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Magnitude and Kinetics of T Cell and Antibody Responses During H1N1pdm09 Infection in Inbred Babraham Pigs and Outbred Pigs by Edmans, Matthew, McNee, Adam, Porter, Emily, Vatzia, Eleni, Paudyal, Basu, Martini, Veronica, Gubbins, Simon, Francis, Ore, Harley, Ross, Thomas, Amy, Burt, Rachel, Morgan, Sophie, Fuller, Anna, Sewell, Andrew, Charleston, Bryan, Bailey, Mick, Tchilian, Elma

“…We have used the pig, a large natural host animal for influenza with many physiological similarities to humans, to characterize αβ, γδ T cell and antibody (Ab)…”
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Porcine Respiratory Coronavirus as a Model for Acute Respiratory Coronavirus Disease by Keep, Sarah, Carr, Brigid Veronica, Lean, Fabian Z X, Fones, Albert, Newman, Joseph, Dowgier, Giulia, Freimanis, Graham, Vatzia, Eleni, Polo, Noemi, Everest, Holly, Webb, Isobel, Mcnee, Adam, Paudyal, Basu, Thakur, Nazia, Nunez, Alejandro, MacLoughlin, Ronan, Maier, Helena, Hammond, John, Bailey, Dalan, Waters, Ryan, Charleston, Bryan, Tuthill, Toby, Britton, Paul, Bickerton, Erica, Tchilian, Elma

“…In the light of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, we have developed a porcine respiratory coronavirus (PRCV) model for…”
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Correction: Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the foot-and-mouth disease virus capsid by Ferretti, Luca, Pérez-Martín, Eva, Zhang, Fuquan, Maree, François, de Klerk-Lorist, Lin-Mari, van Schalkwykc, Louis, Juleff, Nicholas D, Charleston, Bryan, Ribeca, Paolo

“…[This corrects the article DOI: 10.1371/journal.ppat.1008235.]…”
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Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig by Tungatt, Katie, Dolton, Garry, Morgan, Sophie B, Attaf, Meriem, Fuller, Anna, Whalley, Thomas, Hemmink, Johanneke D, Porter, Emily, Szomolay, Barbara, Montoya, Maria, Hammond, John A, Miles, John J, Cole, David K, Townsend, Alain, Bailey, Mick, Rizkallah, Pierre J, Charleston, Bryan, Tchilian, Elma, Sewell, Andrew K

“…There is increasing evidence that induction of local immune responses is a key component of effective vaccines. For respiratory pathogens, for example…”
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Isolation of Single-Domain Antibody Fragments That Preferentially Detect Intact (146S) Particles of Foot-and-Mouth Disease Virus for Use in Vaccine Quality Control by Harmsen, Michiel M, Seago, Julian, Perez, Eva, Charleston, Bryan, Eblé, Phaedra L, Dekker, Aldo

“…Intact (146S) foot-and-mouth disease virus (FMDVs) can dissociate into specific (12S) viral capsid degradation products. FMD vaccines normally consist of…”
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The heterogeneous herd: Drivers of close‐contact variation in African buffalo and implications for pathogen invasion by Rushmore, Julie, Beechler, Brianna R., Tavalire, Hannah, Gorsich, Erin E., Charleston, Bryan, Devan‐Song, Anne, Glidden, Caroline K., Jolles, Anna E.

“…Many infectious pathogens are shared through social interactions, and examining host connectivity has offered valuable insights for understanding patterns of…”
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Induction of a Cross-Reactive CD8+ T Cell Response following Foot-and-Mouth Disease Virus Vaccination by GUZMAN, Efrain, TAYLOR, Geraldine, CHARLESTON, Bryan, ELLIS, Shirley A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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