Search Results - "Charles Marshall"

Five palaeobiological laws needed to understand the evolution of the living biota by Marshall, Charles R.

“…The foundations of several disciplines can be expressed as simple quantitative laws, for example, Newton's laws or the laws of thermodynamics. Here I present…”
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Using the Fossil Record to Evaluate Timetree Timescales by Marshall, Charles R.

“…The fossil and geologic records provide the primary data used to established absolute timescales for timetrees. For the paleontological evaluation of proposed…”
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Diversity dynamics: molecular phylogenies need the fossil record by Quental, Tiago B., Marshall, Charles R.

“…Over the last two decades, new tools in the analysis of molecular phylogenies have enabled study of the diversification dynamics of living clades in the…”
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EXPLAINING THE CAMBRIAN “EXPLOSION” OF ANIMALS by Marshall, Charles R

“…The Cambrian “explosion” is a unique episode in Earth history, when essentially all the animal phyla first appear in the fossil record. A variety of…”
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Deep cervical lymph node ligation aggravates AD‐like pathology of APP/PS1 mice by Wang, Linmei, Zhang, Yanli, Zhao, Ying, Marshall, Charles, Wu, Ting, Xiao, Ming

“…The imbalance between production and clearance of amyloid‐beta (Aβ) is a key step in the onset and development of Alzheimer’s disease (AD). Therefore, reducing…”
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A Simple Method for Bracketing Absolute Divergence Times on Molecular Phylogenies Using Multiple Fossil Calibration Points by Marshall, Charles R.

“…A central challenge facing the temporal calibration of molecular phylogenies is finding a quantitative method for estimating maximum age constraints on lineage…”
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Hearing and dementia: from ears to brain by Johnson, Jeremy C S, Marshall, Charles R, Weil, Rimona S, Bamiou, Doris-Eva, Hardy, Chris J D, Warren, Jason D

“…The association between hearing impairment and dementia has emerged as a major public health challenge, with significant opportunities for earlier diagnosis,…”
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The uncertain role of diversity dependence in species diversification and the need to incorporate time-varying carrying capacities by Marshall, Charles R., Quental, Tiago B.

“…There is no agreement among palaeobiologists or biologists as to whether, or to what extent, there are limits on diversification and species numbers. Here, we…”
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How the Red Queen Drives Terrestrial Mammals to Extinction by Quental, Tiago B., Marshall, Charles R.

“…Most species disappear by the processes of background extinction, yet those processes are poorly understood. We analyzed the evolutionary dynamics of 19…”
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The true tempo of evolutionary radiation and decline revealed on the Hawaiian archipelago by Lim, Jun Y., Marshall, Charles R.

“…A geologically informed model of the relationship between changing island area and species richness for the Hawaiian archipelago reveals the rates of species…”
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Quantitative evidence for dimorphism suggests sexual selection in the maxillary caniniform process of Placerias hesternus by Pinto, James L, Marshall, Charles R, Nesbitt, Sterling J, Varajão de Latorre, Daniel

“…Placerias hesternus, a Late Triassic dicynodont, is one of the last megafaunal synapsids of the Mesozoic. The species has a tusk-like projection on its…”
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Preparing for disease-modifying dementia therapies in the UK by Cooper, Claudia, Marshall, Charles R., Schott, Jonathan M., Banerjee, Sube

“…Although lecanemab has been licensed for use in the UK, the systems to deliver this or similar disease-modifying therapies do not exist. These systems need to…”
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Origin and diversification of living cycads: a cautionary tale on the impact of the branching process prior in Bayesian molecular dating by Condamine, Fabien L, Nagalingum, Nathalie S, Marshall, Charles R, Morlon, Hélène

“…Bayesian relaxed-clock dating has significantly influenced our understanding of the timeline of biotic evolution. This approach requires the use of priors on…”
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Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England by Alothman, Danah, Marshall, Charles R., Tyrrell, Edward, Lewis, Sarah, Card, Timothy, Fogarty, Andrew

“…Objective To examine the relative risk of suicide mortality in patients with Huntington’s disease (HD). Methods A case–control study design was used. We used…”
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A tip of the hat to evolutionary change by Marshall, Charles R.

“…The relative roles of biological and environmental factors in driving evolutionary change have been unclear. Now fossil analysis shows that their action…”
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Epidemiological and cohort study finds no association between COVID-19 and Guillain-Barré syndrome by Keddie, Stephen, Pakpoor, Julia, Mousele, Christina, Pipis, Menelaos, Machado, Pedro M, Foster, Mark, Record, Christopher J, Keh, Ryan Y S, Fehmi, Janev, Paterson, Ross W, Bharambe, Viraj, Clayton, Lisa M, Allen, Claire, Price, Olivia, Wall, Jasmine, Kiss-Csenki, Annamaria, Rathnasabapathi, Devi Priya, Geraldes, Ruth, Yermakova, Tatyana, King-Robson, Joshua, Zosmer, Maya, Rajakulendran, Sanjeev, Sumaria, Sheetal, Farmer, Simon F, Nortley, Ross, Marshall, Charles R, Newman, Edward J, Nirmalananthan, Niranjanan, Kumar, Guru, Pinto, Ashwin A, Holt, James, Lavin, Tim M, Brennan, Kathryn M, Zandi, Michael S, Jayaseelan, Dipa L, Pritchard, Jane, Hadden, Robert D M, Manji, Hadi, Willison, Hugh J, Rinaldi, Simon, Carr, Aisling S, Lunn, Michael P

“…Reports of Guillain-Barré syndrome (GBS) have emerged during the Coronavirus disease 2019 (COVID-19) pandemic. This epidemiological and cohort study sought to…”
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Variable impact of late-Quaternary megafaunal extinction in causing ecological state shifts in North and South America by Barnosky, Anthony D., Lindsey, Emily L., Villavicencio, Natalia A., Bostelmann, Enrique, Hadly, Elizabeth A., Wanket, James, Marshall, Charles R.

“…Loss of megafauna, an aspect of defaunation, can precipitate many ecological changes over short time scales. We examine whether megafauna loss can also explain…”
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Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance by Feng, Weixi, Zhang, Yanli, Wang, Ze, Xu, Hanrong, Wu, Ting, Marshall, Charles, Gao, Junying, Xiao, Ming

“…Abstract Background Soluble beta-amyloid (Aβ) can be cleared from the brain through various mechanisms including enzymatic degradation, glial cell…”
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Primary progressive aphasia: a clinical approach by Marshall, Charles R., Hardy, Chris J. D., Volkmer, Anna, Russell, Lucy L., Bond, Rebecca L., Fletcher, Phillip D., Clark, Camilla N., Mummery, Catherine J., Schott, Jonathan M., Rossor, Martin N., Fox, Nick C., Crutch, Sebastian J., Rohrer, Jonathan D., Warren, Jason D.

“…The primary progressive aphasias are a heterogeneous group of focal ‘language-led’ dementias that pose substantial challenges for diagnosis and management…”
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Has the Earth’s sixth mass extinction already arrived? by Barnosky, Anthony D., Matzke, Nicholas, Tomiya, Susumu, Wogan, Guinevere O. U., Swartz, Brian, Quental, Tiago B., Marshall, Charles, McGuire, Jenny L., Lindsey, Emily L., Maguire, Kaitlin C., Mersey, Ben, Ferrer, Elizabeth A.

“…Mass extinctions: are we there yet? Palaeontologists recognize five major extinction events from the fossil record, with the most recent, the Cretaceous mass…”
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