Search Results - "Charles, John B"
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The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
Published in Science (American Association for the Advancement of Science) (12-04-2019)“…To understand the health impact of long-duration spaceflight, one identical twin astronaut was monitored before, during, and after a 1-year mission onboard the…”
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Multisystem Toxicity in Cancer: Lessons from NASA’s Countermeasures Program
Published in Cell (14-11-2019)“…Astronauts and cancer patients are subject to similar multisystem physiological toxicities. Over the past sixty years, NASA developed a state-of-the-art…”
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Historical Review of Lower Body Negative Pressure Research in Space Medicine
Published in Aerospace medicine and human performance (01-07-2015)“…Cephalad redistribution of intravascular and extravascular fluid occurs as a result of weightlessness during spaceflight. This provokes cardiovascular,…”
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The Bohannon Hypothesis
Published in Aerospace medicine and human performance (01-11-2015)Get more information
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The impact of sex and gender on adaptation to space: executive summary
Published in Journal of women's health (Larchmont, N.Y. 2002) (01-11-2014)“…This review article is a compendium of six individual manuscripts, a Commentary, and an Executive Summary. This body of work is entitled "The Impact of Sex and…”
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Practicing for space underwater: inventing neutral buoyancy training, 1963–1968
Published in Endeavour (New series) (01-09-2015)“…Neutral buoyancy's value was far from obvious when human spaceflight began in 1961. Starting in 1964, Environmental Research Associates, a tiny company in the…”
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Biomedical findings from NASA’s Project Mercury: a case series
Published in NPJ microgravity (13-03-2018)“…The United States first sent humans into space during six flights of Project Mercury from May 1961 to May 1963. These flights were brief, with durations…”
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Microgravity decreases heart rate and arterial pressure in humans
Published in Journal of applied physiology (1985) (01-03-1996)“…Spaceflight causes adaptive changes in cardiovascular physiology, such as postflight orthostatic intolerance, that can have deleterious effects on astronauts…”
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Maximal exercise as a countermeasure to orthostatic intolerance after spaceflight
Published in Medicine and science in sports and exercise (01-01-2001)“…Previous investigators have suggested that maximal exercise performed 24 h before the end of bed rest, a spaceflight analog, restores prebed rest plasma…”
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Body mass changes during long-duration spaceflight
Published in Aviation, space, and environmental medicine (01-09-2014)“…During early spaceflights, many crewmembers did not meet their caloric requirements and consequently lost body mass during flight, as assessed by a decrease in…”
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Evaluation of Cardiac Rhythm Disturbances During Extravehicular Activity
Published in The American journal of cardiology (15-04-1997)“…This study represents the first systematic evaluation of dysrhythmias before, during, and after spaceflight including extravehicular activity (EVA). The data,…”
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Revisiting the needs for artificial gravity during deep space missions
Published in REACH (01-03-2016)“…In the past 15years, several group studies have identified the need to validate the role of artificial gravity (AG) as countermeasure to physiological…”
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Body mass changes during long-duration spaceflight: response
Published in Aviation, space, and environmental medicine (01-12-2014)Get full text
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18th IAA humans in space meeting, Houston
Published in Acta astronautica (01-11-2013)Get full text
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Human health and performance for long-duration spaceflight
Published in Aviation, space, and environmental medicine (01-06-2008)“…Future long-duration spaceflights are now being planned to the Moon and Mars as a part of the "Vision for Space Exploration" program initiated by NASA in 2004…”
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Heart rate dynamics during long-term space flight: report on Mir cosmonauts
Published in The American heart journal (01-07-1994)Get more information
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Space sickness and fluid shifts: a hypothesis
Published in Journal of clinical pharmacology (01-06-1994)“…In a sample of 64 first-time Space Shuttle crew members, 9 preflight variables related to fluid, electrolyte, and cardiovascular status were previously found…”
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Opportunities for research in space life sciences aboard commercial suborbital flights
Published in Aviation, space, and environmental medicine (01-11-2009)“…The emergence of commercial suborbital spaceflight offers a wide range of new research and development opportunities for those in the space life sciences…”
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Cardiovascular responses to standing: effect of hydration
Published in Journal of clinical pharmacology (01-05-1994)“…Many astronauts experience intolerance to orthostatic stress after space flight, despite the ingestion of salt tablets and water equivalent to 0.9% saline just…”
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Use of lower body negative pressure to counter symptoms of orthostatic intolerance in patients, bed rest subjects, and astronauts
Published in Journal of clinical pharmacology (01-11-1993)“…This report briefly discusses some aspects of autonomic cardiovascular dysfunction as related to changes in orthostatic function in patients, bed rest…”
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