Search Results - "Charles, Anne Laure"

Sarcopenia and peripheral arterial disease: a systematic review by Pizzimenti, Mégane, Meyer, Alain, Charles, Anne‐Laure, Giannini, Margherita, Chakfé, Nabil, Lejay, Anne, Geny, Bernard

“…Background Patients with lower extremity peripheral arterial disease (PAD) and sarcopenia are a population at risk requiring specific and targeted care. The…”
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Mitochondria: An Organelle of Bacterial Origin Controlling Inflammation by Meyer, Alain, Laverny, Gilles, Bernardi, Livio, Charles, Anne Laure, Alsaleh, Ghada, Pottecher, Julien, Sibilia, Jean, Geny, Bernard

“…Inflammation is a cellular and molecular response to infection and/or tissues injury. While a suited inflammatory response in intensity and time allows for…”
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Targeting Mitochondrial Metabolic Dysfunction in Pulmonary Hypertension: Toward New Therapeutic Approaches? by Riou, Marianne, Enache, Irina, Sauer, François, Charles, Anne-Laure, Geny, Bernard

“…Pulmonary arterial hypertension (PAH) is a rare disease characterized by pulmonary vascular remodeling leading to right heart failure and death. To date,…”
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Digestive n‐6 Lipid Oxidation, a Key Trigger of Vascular Dysfunction and Atherosclerosis in the Western Diet: Protective Effects of Apple Polyphenols by Bolea, Gaëtan, Philouze, Clothilde, Dubois, Mathilde, Risdon, Sydney, Humberclaude, Anaïs, Ginies, Christian, Charles, Anne‐Laure, Geny, Bernard, Reboul, Cyril, Arnaud, Claire, Dufour, Claire, Meyer, Grégory

“…Scope A main risk factor of atherosclerosis is a Western diet (WD) rich in n‐6 polyunsaturated fatty acids (PUFAs) sensitive to oxidation. Their oxidation can…”
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Chronology of mitochondrial and cellular events during skeletal muscle ischemia-reperfusion by Paradis, Stéphanie, Charles, Anne-Laure, Meyer, Alain, Lejay, Anne, Scholey, James W, Chakfé, Nabil, Zoll, Joffrey, Geny, Bernard

“…Peripheral artery disease (PAD) is a common circulatory disorder of the lower limb arteries that reduces functional capacity and quality of life of patients…”
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Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1 by BOUITBIR, Jamal, CHARLES, Anne-Laure, ECHANIZ-LAGUNA, Andoni, KINDO, Michel, DAUSSIN, Frederic, AUWERX, Johan, PIQUARD, François, GENY, Bernard, ZOLL, Joffrey

“…Statins protect against cardiovascular-related mortality but induce skeletal muscle toxicity. To investigate mechanisms of statins, we tested the hypothesis…”
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Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis by Singh, François, Charles, Anne-Laure, Schlagowski, Anna-Isabel, Bouitbir, Jamal, Bonifacio, Annalisa, Piquard, François, Krähenbühl, Stephan, Geny, Bernard, Zoll, Joffrey

“…Even though oxidative stress damage from excessive production of ROS is a well known phenomenon, the impact of reductive stress remains poorly understood. This…”
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Statins Trigger Mitochondrial Reactive Oxygen Species-Induced Apoptosis in Glycolytic Skeletal Muscle by Bouitbir, Jamal, Singh, François, Charles, Anne-Laure, Schlagowski, Anna-Isabel, Bonifacio, Annalisa, Echaniz-Laguna, Andoni, Geny, Bernard, Krähenbühl, Stephan, Zoll, Joffrey

“…Although statins are the most widely used cholesterol-lowering agents, they are associated with a variety of muscle complaints. The goal of this study was to…”
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Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients by Mallard, Joris, Hucteau, Elyse, Charles, Anne‐Laure, Bender, Laura, Baeza, Claire, Pélissie, Mathilde, Trensz, Philippe, Pflumio, Carole, Kalish‐Weindling, Michal, Gény, Bernard, Schott, Roland, Favret, Fabrice, Pivot, Xavier, Hureau, Thomas J., Pagano, Allan F.

“…Background Chemotherapy is extensively used to treat breast cancer and is associated with skeletal muscle deconditioning, which is known to reduce patients'…”
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Mitochondria: Mitochondrial participation in ischemia–reperfusion injury in skeletal muscle by Lejay, Anne, Meyer, Alain, Schlagowski, Anna-Isabel, Charles, Anne-Laure, Singh, François, Bouitbir, Jamal, Pottecher, Julien, Chakfé, Nabil, Zoll, Joffrey, Geny, Bernard

“…Irrespective of the organ involved, restoration of blood flow to ischemic tissue is vital, although reperfusion per se is deleterious. In the setting of…”
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NButGT Reinforces the Beneficial Effects of Epinephrine on Cardiac Mitochondrial Respiration, Lactatemia and Cardiac Output in Experimental Anaphylactic Shock by Oulehri, Walid, Persello, Antoine, Blangy-Letheule, Angelique, Tacquard, Charles, Rozec, Bertrand, Charles, Anne-Laure, Geny, Bernard, Lauzier, Benjamin, Mertes, Paul Michel, Collange, Olivier

“…Anaphylactic shock (AS) is the most severe form of acute systemic hypersensitivity reaction. Although epinephrine can restore patients' hemodynamics, it might…”
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Cumulative Deleterious Effects of Tetrahydrocannabinoid (THC) and Ethanol on Mitochondrial Respiration and Reactive Oxygen Species Production Are Enhanced in Old Isolated Cardiac Mitochondria by Charles, Anne-Laure, Charloux, Anne, Vogel, Thomas, Raul, Jean-Sébastien, Kindo, Michel, Wolff, Valérie, Geny, Bernard

“…Delta 9 tetrahydrocannabinol (THC), the main component of cannabis, has adverse effects on the cardiovascular system, but whether concomitant ethanol (EtOH)…”
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Targeting Mitochondrial Dynamics during Lower-Limb Ischemia Reperfusion in Young and Old Mice: Effect of Mitochondrial Fission Inhibitor-1 (mDivi-1) by Paradis, Stéphanie, Charles, Anne-Laure, Giannini, Margherita, Meyer, Alain, Lejay, Anne, Talha, Samy, Laverny, Gilles, Charloux, Anne, Geny, Bernard

“…Peripheral arterial disease (PAD) strikes more than 200 million people worldwide and has a severe prognosis by potentially leading to limb amputation and/or…”
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Octanoic Acid-Enrichment Diet Improves Endurance Capacity and Reprograms Mitochondrial Biogenesis in Skeletal Muscle of Mice by Charlot, Anouk, Morel, Lucas, Bringolf, Anthony, Georg, Isabelle, Charles, Anne-Laure, Goupilleau, Fabienne, Geny, Bernard, Zoll, Joffrey

“…Background: Medium Chain Fatty Acids (MCFAs) are a dietary supplement that exhibit interesting properties, due to their smaller molecular size. The acute…”
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Changes in Macronutrients during Dieting Lead to Weight Cycling and Metabolic Complications in Mouse Model by Charlot, Anouk, Bringolf, Anthony, Debrut, Léa, Mallard, Joris, Charles, Anne-Laure, Crouchet, Emilie, Duteil, Delphine, Geny, Bernard, Zoll, Joffrey

“…Weight cycling is a major challenge in obesity management. Caloric restriction is known to promote this phenomenon, but the impact of macronutrient changes…”
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Peripheral Blood Mononuclear Cells and Platelets Mitochondrial Dysfunction, Oxidative Stress, and Circulating mtDNA in Cardiovascular Diseases by Alfatni, Abrar, Riou, Marianne, Charles, Anne-Laure, Meyer, Alain, Barnig, Cindy, Andres, Emmanuel, Lejay, Anne, Talha, Samy, Geny, Bernard

“…Cardiovascular diseases (CVDs) are devastating disorders and the leading cause of mortality worldwide. The pathophysiology of cardiovascular diseases is…”
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Atorvastatin treatment reduces exercise capacities in rats: involvement of mitochondrial impairments and oxidative stress by BOUITBIR, Jamal, CHARLES, Anne-Laure, RASSENEUR, Laurence, DUFOUR, Stéphane, PIQUARD, François, GENY, Bernard, ZOLL, Joffrey

“…Physical exercise exacerbates the cytotoxic effects of statins in skeletal muscle. Mitochondrial impairments may play an important role in the development of…”
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A single chemotherapy administration induces muscle atrophy, mitochondrial alterations and apoptosis in breast cancer patients by Mallard, Joris, Hucteau, Elyse, Bender, Laura, Moinard‐Butot, Fabien, Rochelle, Emma, Boutonnet, Lauréline, Grandperrin, Antoine, Schott, Roland, Pflumio, Carole, Trensz, Philippe, Kalish‐Weindling, Michal, Charles, Anne‐Laure, Gény, Bernard, Favret, Fabrice, Pivot, Xavier, Hureau, Thomas J., Pagano, Allan F.

“…Background Breast cancer patients are commonly treated with sequential administrations of epirubicin–cyclophosphamide (EC) and paclitaxel (TAX). The chronic…”
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Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways? by Pottecher, Julien, Adamopoulos, Chris, Lejay, Anne, Bouitbir, Jamal, Charles, Anne-Laure, Meyer, Alain, Singer, Mervyn, Wolff, Valerie, Diemunsch, Pierre, Laverny, Gilles, Metzger, Daniel, Geny, Bernard

“…Diabetic patients respond poorly to revascularization for peripheral arterial disease (PAD) but the underlying mechanisms are not well understood. We aimed to…”
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Resolution of Inflammation after Skeletal Muscle Ischemia–Reperfusion Injury: A Focus on the Lipid Mediators Lipoxins, Resolvins, Protectins and Maresins by Barnig, Cindy, Lutzweiler, Gaetan, Giannini, Margherita, Lejay, Anne, Charles, Anne-Laure, Meyer, Alain, Geny, Bernard

“…Skeletal muscle ischemia reperfusion is very frequent in humans and results not only in muscle destruction but also in multi-organ failure and death via…”
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